Increasing resonance energy transfer upon dilution: A counterintuitive observation in CTAB micelles
We present a comprehensive study of two indocarbocyanines, DiI (1,1′-dioctadecyl-3,3,3′3′-tetramethylindocarbocyanine perchlorate) and DiD (1,1′-dioctadecyl-3,3,3′,3′-tetramethylindodicarbocyanine perchlorate), in water suspensions in the presence of a CTAB surfactant both above and below the critic...
| Autores: | , , , , , , , , |
|---|---|
| Tipo de recurso: | artículo |
| Estado: | Versión publicada |
| Fecha de publicación: | 2021 |
| País: | España |
| Institución: | Consejo Superior de Investigaciones Científicas (CSIC) |
| Repositorio: | DIGITAL.CSIC. Repositorio Institucional del CSIC |
| OAI Identifier: | oai:digital.csic.es:10261/263644 |
| Acceso en línea: | http://hdl.handle.net/10261/263644 https://api.elsevier.com/content/abstract/scopus_id/85114029447 |
| Access Level: | acceso abierto |
| Palabra clave: | Cyanine dyes Fluorescence properties Single-molecule Nanoparticles Scattering |
| id |
ES_62903b0a3a3d5a6cd2b1cff94b8708c4 |
|---|---|
| oai_identifier_str |
oai:digital.csic.es:10261/263644 |
| network_acronym_str |
ES |
| network_name_str |
España |
| repository_id_str |
|
| dc.title.none.fl_str_mv |
Increasing resonance energy transfer upon dilution: A counterintuitive observation in CTAB micelles |
| title |
Increasing resonance energy transfer upon dilution: A counterintuitive observation in CTAB micelles |
| spellingShingle |
Increasing resonance energy transfer upon dilution: A counterintuitive observation in CTAB micelles Delledonne, Andrea Cyanine dyes Fluorescence properties Single-molecule Nanoparticles Scattering |
| title_short |
Increasing resonance energy transfer upon dilution: A counterintuitive observation in CTAB micelles |
| title_full |
Increasing resonance energy transfer upon dilution: A counterintuitive observation in CTAB micelles |
| title_fullStr |
Increasing resonance energy transfer upon dilution: A counterintuitive observation in CTAB micelles |
| title_full_unstemmed |
Increasing resonance energy transfer upon dilution: A counterintuitive observation in CTAB micelles |
| title_sort |
Increasing resonance energy transfer upon dilution: A counterintuitive observation in CTAB micelles |
| dc.creator.none.fl_str_mv |
Delledonne, Andrea Morla Folch, Judit Anzola, Mattia Bertocchi, Francesco Vargas Nadal, Guillem Köber, Mariana Sissa, Cristina Ventosa, Nora Painelli, Anna |
| author |
Delledonne, Andrea |
| author_facet |
Delledonne, Andrea Morla Folch, Judit Anzola, Mattia Bertocchi, Francesco Vargas Nadal, Guillem Köber, Mariana Sissa, Cristina Ventosa, Nora Painelli, Anna |
| author_role |
author |
| author2 |
Morla Folch, Judit Anzola, Mattia Bertocchi, Francesco Vargas Nadal, Guillem Köber, Mariana Sissa, Cristina Ventosa, Nora Painelli, Anna |
| author2_role |
author author author author author author author author |
| dc.contributor.none.fl_str_mv |
Ministero dell'Istruzione, dell'Università e della Ricerca Ministerio de Economía y Competitividad (España) Ministerio de Ciencia, Innovación y Universidades (España) European Commission Generalitat de Catalunya Consejo Superior de Investigaciones Científicas [https://ror.org/02gfc7t72] |
| dc.subject.none.fl_str_mv |
Cyanine dyes Fluorescence properties Single-molecule Nanoparticles Scattering |
| topic |
Cyanine dyes Fluorescence properties Single-molecule Nanoparticles Scattering |
| description |
We present a comprehensive study of two indocarbocyanines, DiI (1,1′-dioctadecyl-3,3,3′3′-tetramethylindocarbocyanine perchlorate) and DiD (1,1′-dioctadecyl-3,3,3′,3′-tetramethylindodicarbocyanine perchlorate), in water suspensions in the presence of a CTAB surfactant both above and below the critical micellar concentration. The very good affinity of the two dyes with CTAB allows them to be brought into aqueous solutions minimizing aggregation phenomena. When the dyes are loaded inside the micelles, stable fluorescent nanostructures are formed that can be exploited for fundamental studies and for imaging applications. Of special interest are micelles loaded with both dyes: indeed, the large local dye concentration inside the micelles allows observing resonance energy transfer in systems where the global dye concentration is maintained at a low level, so that detailed and robust spectroscopic characterization is possible. Quite impressively, the efficiency of resonance energy transfer is boosted when diluting the sample below the critical micellar concentration. This counterintuitive result is explained in terms of the very large affinity between the dyes and CTAB which favors the dynamical formation of small molecular clusters containing both dyes. Fluorescent micelles are widely used in bioimaging and pharmacokinetic applications. More specifically, the observation of resonant energy transfer in micelles or more generally in nanostructures loaded with two dyes is routinely exploited as a way to assess the nanostructure integrity. In this context, our results demonstrate the importance of robust spectroscopic characterization of the relevant systems in different environments in order to safely assess the viability of the integrity test of nanoparticles based on resonant energy transfer. |
| publishDate |
2021 |
| dc.date.none.fl_str_mv |
2021 2022 2022 |
| dc.type.none.fl_str_mv |
info:eu-repo/semantics/article http://purl.org/coar/resource_type/c_6501 Publisher's version info:eu-repo/semantics/publishedVersion |
| format |
article |
| status_str |
publishedVersion |
| dc.identifier.none.fl_str_mv |
http://hdl.handle.net/10261/263644 https://api.elsevier.com/content/abstract/scopus_id/85114029447 |
| url |
http://hdl.handle.net/10261/263644 https://api.elsevier.com/content/abstract/scopus_id/85114029447 |
| dc.language.none.fl_str_mv |
Inglés |
| language_invalid_str_mv |
Inglés |
| dc.relation.none.fl_str_mv |
#PLACEHOLDER_PARENT_METADATA_VALUE# #PLACEHOLDER_PARENT_METADATA_VALUE# #PLACEHOLDER_PARENT_METADATA_VALUE# info:eu-repo/grantAgreement/MICIU/Plan Estatal de investigación Científica y Técnica y de Innovación 2017-2020/CEX2019-000917-S info:eu-repo/grantAgreement/AEI/Plan Estatal de Investigación Científica y Técnica y de Innovación 2017-2020/PID2019-105622RB-I00 info:eu-repo/grantAgreement/EC/H2020/712949 Journal of Materials Chemistry C http://dx.doi.org/10.1039/d1tc02888j Sí |
| dc.rights.none.fl_str_mv |
info:eu-repo/semantics/openAccess |
| eu_rights_str_mv |
openAccess |
| dc.publisher.none.fl_str_mv |
Royal Society of Chemistry (UK) |
| publisher.none.fl_str_mv |
Royal Society of Chemistry (UK) |
| dc.source.none.fl_str_mv |
reponame:DIGITAL.CSIC. Repositorio Institucional del CSIC instname:Consejo Superior de Investigaciones Científicas (CSIC) |
| instname_str |
Consejo Superior de Investigaciones Científicas (CSIC) |
| reponame_str |
DIGITAL.CSIC. Repositorio Institucional del CSIC |
| collection |
DIGITAL.CSIC. Repositorio Institucional del CSIC |
| repository.name.fl_str_mv |
|
| repository.mail.fl_str_mv |
|
| _version_ |
1869409506401714176 |
| spelling |
Increasing resonance energy transfer upon dilution: A counterintuitive observation in CTAB micellesDelledonne, AndreaMorla Folch, JuditAnzola, MattiaBertocchi, FrancescoVargas Nadal, GuillemKöber, MarianaSissa, CristinaVentosa, NoraPainelli, AnnaCyanine dyesFluorescence propertiesSingle-moleculeNanoparticlesScatteringWe present a comprehensive study of two indocarbocyanines, DiI (1,1′-dioctadecyl-3,3,3′3′-tetramethylindocarbocyanine perchlorate) and DiD (1,1′-dioctadecyl-3,3,3′,3′-tetramethylindodicarbocyanine perchlorate), in water suspensions in the presence of a CTAB surfactant both above and below the critical micellar concentration. The very good affinity of the two dyes with CTAB allows them to be brought into aqueous solutions minimizing aggregation phenomena. When the dyes are loaded inside the micelles, stable fluorescent nanostructures are formed that can be exploited for fundamental studies and for imaging applications. Of special interest are micelles loaded with both dyes: indeed, the large local dye concentration inside the micelles allows observing resonance energy transfer in systems where the global dye concentration is maintained at a low level, so that detailed and robust spectroscopic characterization is possible. Quite impressively, the efficiency of resonance energy transfer is boosted when diluting the sample below the critical micellar concentration. This counterintuitive result is explained in terms of the very large affinity between the dyes and CTAB which favors the dynamical formation of small molecular clusters containing both dyes. Fluorescent micelles are widely used in bioimaging and pharmacokinetic applications. More specifically, the observation of resonant energy transfer in micelles or more generally in nanostructures loaded with two dyes is routinely exploited as a way to assess the nanostructure integrity. In this context, our results demonstrate the importance of robust spectroscopic characterization of the relevant systems in different environments in order to safely assess the viability of the integrity test of nanoparticles based on resonant energy transfer.This work is dedicated to Concepció Rovira and Jaume Veciana, inspiring scientists in the field of functional molecular materials. Working with them is a prized privilege and the basis for a solid friendship. AD, MA, FB, CS and AP benefited from the equipment and support of the COMP-HUB Initiative, funded by the “Departments of Excellence” program of the Italian Ministry for Education, University and Research (MIUR, 2018–2022) and acknowledge the support from the high performance computing center at Parma University. JMF, GVN, MK and NV acknowledge support from MINECO through the Severo Ochoa Programme FUNFUTURE (SEV-2015-0496 and CEX2019-000917-S), and the Ministry of Science and Innovation of Spain through the grant PID2019-105622RB-I00 (Mol4Bio), and gratefully acknowledge the financial support received from European Union's Horizon 2020 research and innovation program under the Marie Skłodowska-Curie grant agreement No. 712949 (TECNIOspring PLUS) and from the Agency for Business Competitiveness of the Government of Catalonia.With funding from the Spanish government through the ‘Severo Ochoa Centre of Excellence’ accreditation (CEX2019-000917-S).Peer reviewedRoyal Society of Chemistry (UK)Ministero dell'Istruzione, dell'Università e della RicercaMinisterio de Economía y Competitividad (España)Ministerio de Ciencia, Innovación y Universidades (España)European CommissionGeneralitat de CatalunyaConsejo Superior de Investigaciones Científicas [https://ror.org/02gfc7t72]202220222021info:eu-repo/semantics/articlehttp://purl.org/coar/resource_type/c_6501Publisher's versioninfo:eu-repo/semantics/publishedVersionhttp://hdl.handle.net/10261/263644https://api.elsevier.com/content/abstract/scopus_id/85114029447reponame:DIGITAL.CSIC. Repositorio Institucional del CSICinstname:Consejo Superior de Investigaciones Científicas (CSIC)Inglés#PLACEHOLDER_PARENT_METADATA_VALUE##PLACEHOLDER_PARENT_METADATA_VALUE##PLACEHOLDER_PARENT_METADATA_VALUE#info:eu-repo/grantAgreement/MICIU/Plan Estatal de investigación Científica y Técnica y de Innovación 2017-2020/CEX2019-000917-Sinfo:eu-repo/grantAgreement/AEI/Plan Estatal de Investigación Científica y Técnica y de Innovación 2017-2020/PID2019-105622RB-I00info:eu-repo/grantAgreement/EC/H2020/712949Journal of Materials Chemistry Chttp://dx.doi.org/10.1039/d1tc02888jSíinfo:eu-repo/semantics/openAccessoai:digital.csic.es:10261/2636442026-05-22T06:33:51Z |
| score |
15,812455 |