Formation of the glycine isomer glycolamide (NH2C(O)CH2OH) on the surfaces of interstellar ice grains: Insights from atomistic simulations

Context. Syn-glycolamide, a glycine isomer, has recently been detected in the G+0.693-0.027 molecular cloud. Investigations into its formation in the interstellar medium could offer insights into synthetic routes leading to glycine in prebiotic environments. Aims. Quantum chemical simulations on gly...

Descripción completa

Detalles Bibliográficos
Autores: Perrero, Jessica|||0000-0003-2161-9120, Alessandrini, Silvia|||0000-0003-3152-3261, Ye, H., Puzzarini, Cristina|||0000-0002-2395-8532, Rimola, Albert|||0000-0002-9637-4554
Tipo de recurso: artículo
Fecha de publicación:2025
País:España
Institución:Universitat Autònoma de Barcelona
Repositorio:Dipòsit Digital de Documents de la UAB
Idioma:inglés
OAI Identifier:oai:ddd.uab.cat:324285
Acceso en línea:https://ddd.uab.cat/record/324285
https://dx.doi.org/urn:doi:10.1051/0004-6361/202554330
Access Level:acceso abierto
Palabra clave:Astrochemistry
Molecular processes
ISM: Abundances
ISM: molecules
Descripción
Sumario:Context. Syn-glycolamide, a glycine isomer, has recently been detected in the G+0.693-0.027 molecular cloud. Investigations into its formation in the interstellar medium could offer insights into synthetic routes leading to glycine in prebiotic environments. Aims. Quantum chemical simulations on glycolamide (NH2C(O)CH2OH) formation on interstellar ice mantles, mimicked by a water ice cluster model, are presented. Methods. In this paper, we modeled glycolamide synthesis considering a stepwise process: the coupling between formaldehyde (H2CO) and the radical of formamide (NH2CO•) occurs first, forming the glycolamide precursor NH2C(=O)CH2O•, which is then hydrogenated to give anti-glycolamide. We hypothesize that anti-to-syn interconversion occurs in conjunction with glycolamide desorption from the ice surface. Results. The reaction barrier for NH2C(O)CH2O• formation varies from 9 to 26 kJ mol-1, depending on surface binding sites. Kinetic studies indicate that this reaction step is feasible in environments with a T > 35 K, until desorption of the reactants. The hydrogenation step leading to anti-glycolamide presents almost no energy barrier due to the easy H atom diffusion toward the NH2C(O)CH2O• intermediate. However, it competes with the extraction of an H atom from the formyl group of NH2C(O)CH2O•, which leads to formyl formamide, NH2C(O)CHO, and H2. Nonetheless, according to our results, anti-glycolamide formation is predicted to be the most favored reactive channel.