Comparative study of methods for cycle length estimation in fractionated electrograms of atrial fibrillation

Atrial cycle length (CL) is an important feature for the analysis of electrogram (EGM) characteristics acquired during catheter ablation (CA) of atrial fibrillation (AF), the commonest cardiac arrhythmia. Nevertheless, a robust ACL estimator requires the precise detection of local activation waves (...

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Detalhes bibliográficos
Autores: Osorio, Diego, Vraka, Aikaterini, Moreno Arribas, José, Bertomeu González, Vicente, Alcaraz Martínez, Raúl, Rieta, José J.
Formato: artículo
Fecha de publicación:2022
País:España
Recursos:Universidad de Castilla-La Mancha
Repositorio:RUIdeRA. Repositorio Institucional de la UCLM
OAI Identifier:oai:ruidera.uclm.es:10578/43620
Acesso em linha:https://doi.org/10.3390/jpm12101712
https://hdl.handle.net/10578/43620
Access Level:acceso abierto
Palavra-chave:Atrial fibrillation
Comparison
Complex fractionated atrial electrograms
Cycle length
Detection
Electrogram
Invasive recordings
Local activation waves
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spelling Comparative study of methods for cycle length estimation in fractionated electrograms of atrial fibrillationOsorio, DiegoVraka, AikateriniMoreno Arribas, JoséBertomeu González, VicenteAlcaraz Martínez, RaúlRieta, José J.Atrial fibrillationComparisonComplex fractionated atrial electrogramsCycle lengthDetectionElectrogramInvasive recordingsLocal activation wavesAtrial cycle length (CL) is an important feature for the analysis of electrogram (EGM) characteristics acquired during catheter ablation (CA) of atrial fibrillation (AF), the commonest cardiac arrhythmia. Nevertheless, a robust ACL estimator requires the precise detection of local activation waves (LAWs), which still remains a challenge. This work aims to compare the performance in (CL) estimation, especially under fractionated EGMs, of three different LAW detection methods relying on different operation strategies. The methods are based on the hyperbolic tangent (HT) function, an adaptive amplitude threshold (AAT) and a (CL) iteration (ACLI), respectively. For each method, LAW detection has been assessed with respect to manual annotations made by two experts and performance has been estimated by confusion matrix and mean and individual (CL) error calculation by EGM types of fractionation. The influence of EGM length on the individual (CL) error has been additionally considered. For the HT method, accuracy, sensitivity and precision were 92.77–100%, while for the AAT and ACLI methods they were 78.89–99.91% for all EGM types. The CL error on the HT method was lower than AAT and ACLI methods (up to 12 ms versus up to 20 ms), with the difference being more prominent in complex EGMs. The HT method also showed the lowest dependency on EGM length, presenting the lowest and least variable error values. Therefore, the HT method achieves higher performance in (CL) estimation in comparison with previous LAW detection techniques. The high robustness and precision demonstrated by this method suggest its implementation on CA mapping devices for a more successful location of ablation targets and improved results during CA procedures.MDPI202520252022info:eu-repo/semantics/articleapplication/pdfapplication/pdfhttps://doi.org/10.3390/jpm12101712https://hdl.handle.net/10578/43620reponame:RUIdeRA. Repositorio Institucional de la UCLMinstname:Universidad de Castilla-La ManchaInglésinfo:eu-repo/semantics/openAccessoai:ruidera.uclm.es:10578/436202026-05-27T07:36:41Z
dc.title.none.fl_str_mv Comparative study of methods for cycle length estimation in fractionated electrograms of atrial fibrillation
title Comparative study of methods for cycle length estimation in fractionated electrograms of atrial fibrillation
spellingShingle Comparative study of methods for cycle length estimation in fractionated electrograms of atrial fibrillation
Osorio, Diego
Atrial fibrillation
Comparison
Complex fractionated atrial electrograms
Cycle length
Detection
Electrogram
Invasive recordings
Local activation waves
title_short Comparative study of methods for cycle length estimation in fractionated electrograms of atrial fibrillation
title_full Comparative study of methods for cycle length estimation in fractionated electrograms of atrial fibrillation
title_fullStr Comparative study of methods for cycle length estimation in fractionated electrograms of atrial fibrillation
title_full_unstemmed Comparative study of methods for cycle length estimation in fractionated electrograms of atrial fibrillation
title_sort Comparative study of methods for cycle length estimation in fractionated electrograms of atrial fibrillation
dc.creator.none.fl_str_mv Osorio, Diego
Vraka, Aikaterini
Moreno Arribas, José
Bertomeu González, Vicente
Alcaraz Martínez, Raúl
Rieta, José J.
author Osorio, Diego
author_facet Osorio, Diego
Vraka, Aikaterini
Moreno Arribas, José
Bertomeu González, Vicente
Alcaraz Martínez, Raúl
Rieta, José J.
author_role author
author2 Vraka, Aikaterini
Moreno Arribas, José
Bertomeu González, Vicente
Alcaraz Martínez, Raúl
Rieta, José J.
author2_role author
author
author
author
author
dc.subject.none.fl_str_mv Atrial fibrillation
Comparison
Complex fractionated atrial electrograms
Cycle length
Detection
Electrogram
Invasive recordings
Local activation waves
topic Atrial fibrillation
Comparison
Complex fractionated atrial electrograms
Cycle length
Detection
Electrogram
Invasive recordings
Local activation waves
description Atrial cycle length (CL) is an important feature for the analysis of electrogram (EGM) characteristics acquired during catheter ablation (CA) of atrial fibrillation (AF), the commonest cardiac arrhythmia. Nevertheless, a robust ACL estimator requires the precise detection of local activation waves (LAWs), which still remains a challenge. This work aims to compare the performance in (CL) estimation, especially under fractionated EGMs, of three different LAW detection methods relying on different operation strategies. The methods are based on the hyperbolic tangent (HT) function, an adaptive amplitude threshold (AAT) and a (CL) iteration (ACLI), respectively. For each method, LAW detection has been assessed with respect to manual annotations made by two experts and performance has been estimated by confusion matrix and mean and individual (CL) error calculation by EGM types of fractionation. The influence of EGM length on the individual (CL) error has been additionally considered. For the HT method, accuracy, sensitivity and precision were 92.77–100%, while for the AAT and ACLI methods they were 78.89–99.91% for all EGM types. The CL error on the HT method was lower than AAT and ACLI methods (up to 12 ms versus up to 20 ms), with the difference being more prominent in complex EGMs. The HT method also showed the lowest dependency on EGM length, presenting the lowest and least variable error values. Therefore, the HT method achieves higher performance in (CL) estimation in comparison with previous LAW detection techniques. The high robustness and precision demonstrated by this method suggest its implementation on CA mapping devices for a more successful location of ablation targets and improved results during CA procedures.
publishDate 2022
dc.date.none.fl_str_mv 2022
2025
2025
dc.type.none.fl_str_mv info:eu-repo/semantics/article
format article
dc.identifier.none.fl_str_mv https://doi.org/10.3390/jpm12101712
https://hdl.handle.net/10578/43620
url https://doi.org/10.3390/jpm12101712
https://hdl.handle.net/10578/43620
dc.language.none.fl_str_mv Inglés
language_invalid_str_mv Inglés
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
application/pdf
dc.publisher.none.fl_str_mv MDPI
publisher.none.fl_str_mv MDPI
dc.source.none.fl_str_mv reponame:RUIdeRA. Repositorio Institucional de la UCLM
instname:Universidad de Castilla-La Mancha
instname_str Universidad de Castilla-La Mancha
reponame_str RUIdeRA. Repositorio Institucional de la UCLM
collection RUIdeRA. Repositorio Institucional de la UCLM
repository.name.fl_str_mv
repository.mail.fl_str_mv
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score 15.198674

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