On the design of lignin reinforced acrylic acid/hyaluronic acid adhesive hydrogels with conductive PEDOT:HA nanoparticles

[EN] Hydrogels are of great importance in biomedical engineering. They possess the ability to mimic bodily soft tissues, and this allows exciting possibilities for applications such as tissue engineering, drug delivery, and wound healing, however much work remains on stability and mechanical robustn...

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Autores: Winters, Caitriona, Culebras, Mario, Collins, Maurice N., Carsí Rosique, Marta|||0000-0003-2315-3344, Sanchis Sánchez, María Jesús|||0000-0002-3528-3966
Formato: artículo
Fecha de publicación:2024
País:España
Recursos:Universitat Politècnica de València (UPV)
Repositorio:RiuNet. Repositorio Institucional de la Universitat Politécnica de Valéncia
Idioma:inglés
OAI Identifier:oai:riunet.upv.es:10251/220665
Acesso em linha:https://riunet.upv.es/handle/10251/220665
Access Level:acceso abierto
Palavra-chave:Lignin
Hyaluronic acid
Hydrogels
Conductive
Adhesive
15.- Proteger, restaurar y promover la utilización sostenible de los ecosistemas terrestres, gestionar de manera sostenible los bosques, combatir la desertificación y detener y revertir la degradación de la tierra, y frenar la pérdida de diversidad biológica
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spelling On the design of lignin reinforced acrylic acid/hyaluronic acid adhesive hydrogels with conductive PEDOT:HA nanoparticlesWinters, CaitrionaCulebras, MarioCollins, Maurice N.Carsí Rosique, Marta|||0000-0003-2315-3344Sanchis Sánchez, María Jesús|||0000-0002-3528-3966LigninHyaluronic acidHydrogelsConductiveAdhesive15.- Proteger, restaurar y promover la utilización sostenible de los ecosistemas terrestres, gestionar de manera sostenible los bosques, combatir la desertificación y detener y revertir la degradación de la tierra, y frenar la pérdida de diversidad biológica[EN] Hydrogels are of great importance in biomedical engineering. They possess the ability to mimic bodily soft tissues, and this allows exciting possibilities for applications such as tissue engineering, drug delivery, and wound healing, however much work remains on stability and mechanical robustness to allow for translation to clinical applications. The work herein describes the synthesis and analysis of a biocompatible, versatile hydrogel that has tailorable swelling, high stability when swollen, and thermal stability. The synthesis methods used produce a hydrogel with high elasticity, good mechanical properties, and rapid crosslinking whilst displaying biocompatibility, adhesion, and conductivity. It has been shown that cell viability in the samples is above 80 % in all cases, a Young's Modulus of up to 85 kPa and high swelling degrees were achieved. These materials show potential for use in numerous applications such as adhesive sensors, skin grafts, and drug delivery systems.This publication has emanated from research conducted with the financial support of Science Foundation Ireland under the SFI Research Infrastructure Programme 21/RI/9831. This work was supported by VIBES project. VIBES is a project funded by the European Commission. This project has received funding from the Bio-Based Industries Joint Undertaking (JU) under grant agreement No. 101023190. The JU receives support from the European Union s research and innovation program and the Bio Based Industries ConsortiumElsevierInstituto de Tecnología EléctricaDepartamento de Termodinámica AplicadaInstituto Universitario de Automática e Informática IndustrialEscuela Técnica Superior de Ingeniería IndustrialEuropean CommissionScience Foundation IrelandRepositorio Institucional de la Universitat Politècnica de València Riunet20242024-07-01journal articlehttp://purl.org/coar/resource_type/c_6501VoRhttp://purl.org/coar/version/c_970fb48d4fbd8a85info:eu-repo/semantics/articleapplication/pdfhttps://riunet.upv.es/handle/10251/220665reponame:RiuNet. Repositorio Institucional de la Universitat Politécnica de Valénciainstname:Universitat Politècnica de València (UPV)InglésengEuropean Commission https://doi.org/10.13039/501100000780 H2020 101023190 IMPROVING RECYCLABILITY OF THERMOSET COMPOSITE MATERIALS THROUGH A GREENER RECYCLING TECHNOLOGY BASED ON REVERSIBLE BIOBASED BONDING MATERIALSSanta Fe Institute https://doi.org/10.13039/100011419 21%2FRI%2F9831open accesshttp://purl.org/coar/access_right/c_abf2Reconocimiento (by)http://creativecommons.org/licenses/by/4.0/info:eu-repo/semantics/openAccessoai:riunet.upv.es:10251/2206652026-06-13T07:49:27Z
dc.title.none.fl_str_mv On the design of lignin reinforced acrylic acid/hyaluronic acid adhesive hydrogels with conductive PEDOT:HA nanoparticles
title On the design of lignin reinforced acrylic acid/hyaluronic acid adhesive hydrogels with conductive PEDOT:HA nanoparticles
spellingShingle On the design of lignin reinforced acrylic acid/hyaluronic acid adhesive hydrogels with conductive PEDOT:HA nanoparticles
Winters, Caitriona
Lignin
Hyaluronic acid
Hydrogels
Conductive
Adhesive
15.- Proteger, restaurar y promover la utilización sostenible de los ecosistemas terrestres, gestionar de manera sostenible los bosques, combatir la desertificación y detener y revertir la degradación de la tierra, y frenar la pérdida de diversidad biológica
title_short On the design of lignin reinforced acrylic acid/hyaluronic acid adhesive hydrogels with conductive PEDOT:HA nanoparticles
title_full On the design of lignin reinforced acrylic acid/hyaluronic acid adhesive hydrogels with conductive PEDOT:HA nanoparticles
title_fullStr On the design of lignin reinforced acrylic acid/hyaluronic acid adhesive hydrogels with conductive PEDOT:HA nanoparticles
title_full_unstemmed On the design of lignin reinforced acrylic acid/hyaluronic acid adhesive hydrogels with conductive PEDOT:HA nanoparticles
title_sort On the design of lignin reinforced acrylic acid/hyaluronic acid adhesive hydrogels with conductive PEDOT:HA nanoparticles
dc.creator.none.fl_str_mv Winters, Caitriona
Culebras, Mario
Collins, Maurice N.
Carsí Rosique, Marta|||0000-0003-2315-3344
Sanchis Sánchez, María Jesús|||0000-0002-3528-3966
author Winters, Caitriona
author_facet Winters, Caitriona
Culebras, Mario
Collins, Maurice N.
Carsí Rosique, Marta|||0000-0003-2315-3344
Sanchis Sánchez, María Jesús|||0000-0002-3528-3966
author_role author
author2 Culebras, Mario
Collins, Maurice N.
Carsí Rosique, Marta|||0000-0003-2315-3344
Sanchis Sánchez, María Jesús|||0000-0002-3528-3966
author2_role author
author
author
author
dc.contributor.none.fl_str_mv Instituto de Tecnología Eléctrica
Departamento de Termodinámica Aplicada
Instituto Universitario de Automática e Informática Industrial
Escuela Técnica Superior de Ingeniería Industrial
European Commission
Science Foundation Ireland
Repositorio Institucional de la Universitat Politècnica de València Riunet
dc.subject.none.fl_str_mv Lignin
Hyaluronic acid
Hydrogels
Conductive
Adhesive
15.- Proteger, restaurar y promover la utilización sostenible de los ecosistemas terrestres, gestionar de manera sostenible los bosques, combatir la desertificación y detener y revertir la degradación de la tierra, y frenar la pérdida de diversidad biológica
topic Lignin
Hyaluronic acid
Hydrogels
Conductive
Adhesive
15.- Proteger, restaurar y promover la utilización sostenible de los ecosistemas terrestres, gestionar de manera sostenible los bosques, combatir la desertificación y detener y revertir la degradación de la tierra, y frenar la pérdida de diversidad biológica
description [EN] Hydrogels are of great importance in biomedical engineering. They possess the ability to mimic bodily soft tissues, and this allows exciting possibilities for applications such as tissue engineering, drug delivery, and wound healing, however much work remains on stability and mechanical robustness to allow for translation to clinical applications. The work herein describes the synthesis and analysis of a biocompatible, versatile hydrogel that has tailorable swelling, high stability when swollen, and thermal stability. The synthesis methods used produce a hydrogel with high elasticity, good mechanical properties, and rapid crosslinking whilst displaying biocompatibility, adhesion, and conductivity. It has been shown that cell viability in the samples is above 80 % in all cases, a Young's Modulus of up to 85 kPa and high swelling degrees were achieved. These materials show potential for use in numerous applications such as adhesive sensors, skin grafts, and drug delivery systems.
publishDate 2024
dc.date.none.fl_str_mv 2024
2024-07-01
dc.type.none.fl_str_mv journal article
http://purl.org/coar/resource_type/c_6501
VoR
http://purl.org/coar/version/c_970fb48d4fbd8a85
dc.type.openaire.fl_str_mv info:eu-repo/semantics/article
format article
dc.identifier.none.fl_str_mv https://riunet.upv.es/handle/10251/220665
url https://riunet.upv.es/handle/10251/220665
dc.language.none.fl_str_mv Inglés
eng
language_invalid_str_mv Inglés
language eng
dc.relation.none.fl_str_mv European Commission https://doi.org/10.13039/501100000780 H2020 101023190 IMPROVING RECYCLABILITY OF THERMOSET COMPOSITE MATERIALS THROUGH A GREENER RECYCLING TECHNOLOGY BASED ON REVERSIBLE BIOBASED BONDING MATERIALS
Santa Fe Institute https://doi.org/10.13039/100011419 21%2FRI%2F9831
dc.rights.none.fl_str_mv open access
http://purl.org/coar/access_right/c_abf2
Reconocimiento (by)
http://creativecommons.org/licenses/by/4.0/
dc.rights.openaire.fl_str_mv info:eu-repo/semantics/openAccess
rights_invalid_str_mv open access
http://purl.org/coar/access_right/c_abf2
Reconocimiento (by)
http://creativecommons.org/licenses/by/4.0/
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Elsevier
publisher.none.fl_str_mv Elsevier
dc.source.none.fl_str_mv reponame:RiuNet. Repositorio Institucional de la Universitat Politécnica de Valéncia
instname:Universitat Politècnica de València (UPV)
instname_str Universitat Politècnica de València (UPV)
reponame_str RiuNet. Repositorio Institucional de la Universitat Politécnica de Valéncia
collection RiuNet. Repositorio Institucional de la Universitat Politécnica de Valéncia
repository.name.fl_str_mv
repository.mail.fl_str_mv
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