EPIMHC: a curated database of MHC-binding peptides for customized computational vaccinology
EPIMHC is a relational database of MHC-binding peptides and T cell epitopes that are observed in real proteins. Currently, the database contains 4867 distinct peptide sequences from various sources, including 84 tumor-associated antigens. The EPIMHC database is accessible through a web server that h...
| Autores: | , , , |
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| Tipo de documento: | artigo |
| Data de publicação: | 2005 |
| País: | España |
| Recursos: | Universidad Complutense de Madrid (UCM) |
| Repositório: | Docta Complutense |
| Idioma: | inglês |
| OAI Identifier: | oai:docta.ucm.es:20.500.14352/50385 |
| Acesso em linha: | https://hdl.handle.net/20.500.14352/50385 |
| Access Level: | Acceso aberto |
| Palavra-chave: | 612.017 57:004 Inmunología Biología molecular (Biología) Bioinformática 2412 Inmunología 2415 Biología Molecular |
| Resumo: | EPIMHC is a relational database of MHC-binding peptides and T cell epitopes that are observed in real proteins. Currently, the database contains 4867 distinct peptide sequences from various sources, including 84 tumor-associated antigens. The EPIMHC database is accessible through a web server that has been designed to facilitate research in computational vaccinology. Importantly, peptides resulting from a query can be selected to derive specific motif-matrices. Subsequently, these motif-matrices can be used in combination with a dynamic algorithm for predicting MHC-binding peptides from user-provided protein queries. AVAILABILITY: The EPIMHC database server is hosted by the Dana-Farber Cancer Institute at the site http://immunax.dfci.harvard.edu/bioinformatics/epimhc/ |
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