Synovial fluid examination for the diagnosis of synovial amyloidosis in patients with chronic renal failure undergoing haemodialysis

The diagnosis of synovial amyloidosis is based upon synovial biopsy. Synovial fluid (SF) in seven patients with amyloid arthropathy associated with chronic renal failure undergoing haemodialysis were studied. The SF and synovial samples of 10 consecutive patients with seronegative mono- or oligoarth...

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Detalles Bibliográficos
Autores: Muñoz Gómez, José, Gómez-Pérez, R., Solé Arqués, Manuel, Llopart-Buisán, E.
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:1987
País:España
Institución:Universidad de Barcelona
Repositorio:Dipòsit Digital de la UB
OAI Identifier:oai:diposit.ub.edu:2445/22426
Acceso en línea:https://hdl.handle.net/2445/22426
Access Level:acceso abierto
Palabra clave:Amiloïdosi
Insuficiència renal crònica
Hemodiàlisi
Diagnòstic
Amyloidosis
Chronic renal failure
Hemodialysis
Diagnosis
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spelling Synovial fluid examination for the diagnosis of synovial amyloidosis in patients with chronic renal failure undergoing haemodialysisMuñoz Gómez, JoséGómez-Pérez, R.Solé Arqués, ManuelLlopart-Buisán, E.AmiloïdosiInsuficiència renal crònicaHemodiàlisiDiagnòsticAmyloidosisChronic renal failureHemodialysisDiagnosisThe diagnosis of synovial amyloidosis is based upon synovial biopsy. Synovial fluid (SF) in seven patients with amyloid arthropathy associated with chronic renal failure undergoing haemodialysis were studied. The SF and synovial samples of 10 consecutive patients with seronegative mono- or oligoarthritis served as controls. Six of the seven patients with amyloid positive synovial biopsy specimens showed amyloid in their SF. No amyloid was found in the synovial tissue or fluid of the 10 patients in the control group, the sensitivity being 87.7%. The finding of amyloid in SF was highly reproducible, showing its presence in the same joint on several occasions. The deposits were Congophilia resistant to potassium permanganate pretreatment, and the immunohistochemical analysis proved that they contained beta 2 microglobulin. The high sensitivity and good reproducibility of the method shows that the finding of amyloid in SF is sufficient for the diagnosis of synovial amyloidosis. It is possible to perform immunohisBMJ Group1987info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://hdl.handle.net/2445/22426Articles publicats en revistes (Medicina)reponame:Dipòsit Digital de la UBinstname:Universidad de BarcelonaInglésReproducció digital del document publicat a: http://dx.doi.org/10.1136/ard.46.4.324Annals of the Rheumatic Diseases, 1987, vol. 46, núm. 4, p. 324-326http://dx.doi.org/10.1136/ard.46.4.324(c) BMJ Publishing Group Ltd, 1987info:eu-repo/semantics/openAccessoai:diposit.ub.edu:2445/224262026-05-27T06:46:51Z
dc.title.none.fl_str_mv Synovial fluid examination for the diagnosis of synovial amyloidosis in patients with chronic renal failure undergoing haemodialysis
title Synovial fluid examination for the diagnosis of synovial amyloidosis in patients with chronic renal failure undergoing haemodialysis
spellingShingle Synovial fluid examination for the diagnosis of synovial amyloidosis in patients with chronic renal failure undergoing haemodialysis
Muñoz Gómez, José
Amiloïdosi
Insuficiència renal crònica
Hemodiàlisi
Diagnòstic
Amyloidosis
Chronic renal failure
Hemodialysis
Diagnosis
title_short Synovial fluid examination for the diagnosis of synovial amyloidosis in patients with chronic renal failure undergoing haemodialysis
title_full Synovial fluid examination for the diagnosis of synovial amyloidosis in patients with chronic renal failure undergoing haemodialysis
title_fullStr Synovial fluid examination for the diagnosis of synovial amyloidosis in patients with chronic renal failure undergoing haemodialysis
title_full_unstemmed Synovial fluid examination for the diagnosis of synovial amyloidosis in patients with chronic renal failure undergoing haemodialysis
title_sort Synovial fluid examination for the diagnosis of synovial amyloidosis in patients with chronic renal failure undergoing haemodialysis
dc.creator.none.fl_str_mv Muñoz Gómez, José
Gómez-Pérez, R.
Solé Arqués, Manuel
Llopart-Buisán, E.
author Muñoz Gómez, José
author_facet Muñoz Gómez, José
Gómez-Pérez, R.
Solé Arqués, Manuel
Llopart-Buisán, E.
author_role author
author2 Gómez-Pérez, R.
Solé Arqués, Manuel
Llopart-Buisán, E.
author2_role author
author
author
dc.subject.none.fl_str_mv Amiloïdosi
Insuficiència renal crònica
Hemodiàlisi
Diagnòstic
Amyloidosis
Chronic renal failure
Hemodialysis
Diagnosis
topic Amiloïdosi
Insuficiència renal crònica
Hemodiàlisi
Diagnòstic
Amyloidosis
Chronic renal failure
Hemodialysis
Diagnosis
description The diagnosis of synovial amyloidosis is based upon synovial biopsy. Synovial fluid (SF) in seven patients with amyloid arthropathy associated with chronic renal failure undergoing haemodialysis were studied. The SF and synovial samples of 10 consecutive patients with seronegative mono- or oligoarthritis served as controls. Six of the seven patients with amyloid positive synovial biopsy specimens showed amyloid in their SF. No amyloid was found in the synovial tissue or fluid of the 10 patients in the control group, the sensitivity being 87.7%. The finding of amyloid in SF was highly reproducible, showing its presence in the same joint on several occasions. The deposits were Congophilia resistant to potassium permanganate pretreatment, and the immunohistochemical analysis proved that they contained beta 2 microglobulin. The high sensitivity and good reproducibility of the method shows that the finding of amyloid in SF is sufficient for the diagnosis of synovial amyloidosis. It is possible to perform immunohis
publishDate 1987
dc.date.none.fl_str_mv 1987
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv https://hdl.handle.net/2445/22426
url https://hdl.handle.net/2445/22426
dc.language.none.fl_str_mv Inglés
language_invalid_str_mv Inglés
dc.relation.none.fl_str_mv Reproducció digital del document publicat a: http://dx.doi.org/10.1136/ard.46.4.324
Annals of the Rheumatic Diseases, 1987, vol. 46, núm. 4, p. 324-326
http://dx.doi.org/10.1136/ard.46.4.324
dc.rights.none.fl_str_mv (c) BMJ Publishing Group Ltd, 1987
info:eu-repo/semantics/openAccess
rights_invalid_str_mv (c) BMJ Publishing Group Ltd, 1987
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv BMJ Group
publisher.none.fl_str_mv BMJ Group
dc.source.none.fl_str_mv Articles publicats en revistes (Medicina)
reponame:Dipòsit Digital de la UB
instname:Universidad de Barcelona
instname_str Universidad de Barcelona
reponame_str Dipòsit Digital de la UB
collection Dipòsit Digital de la UB
repository.name.fl_str_mv
repository.mail.fl_str_mv
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score 15,301629

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