Incidence and clinical manifestations of giant cell arteritis in Spain

Fernández-Lozano, Delia|||0000-0001-9650-1296; Hernández-Rodríguez, Iñigo; Narváez, Javier|||0000-0002-1614-8064; Domínguez-Álvaro, Marta|||0000-0002-4057-5971; de Miguel, Eugenio|||0000-0001-5146-1964; Silva-Díaz, Maite|||0000-0003-1904-011X; Belzunegui, Joaquín María; Morales, Clara Moriano; Sánchez, Julio; Galíndez Agirregoikoa, Eva; Aldaroso, Vicente; Abasolo, Lydia; Loricera, Javier|||0000-0003-4754-0277; Garrido-Puñal, Noemi; Moya, Patricia|||0000-0001-8339-5420; Larena, Carmen; Navarro, Vanessa Andrea; Casafont Solé, Ivette|||0000-0002-1004-300X; Calvet, Joan|||0000-0002-0888-5152; Ortiz Sanjuán, Francisco; Salman-Monte, Tarek Carlos|||0000-0002-4676-0174; Castañeda, Santos|||0000-0002-7748-853X; Blanco, Ricardo|||0000-0003-2344-2285; Álvarez, E.D.; Sandoval, T.P.; Fernández, I.G.; Mendizábal-Mateos, J.; Manteca, M.C.F.; del Val del Amo, N.; Rubio, L.H.; Zudaire, I.P.; Courel, L.G.; Polo, R.G.; Vélez, J.R.; Cortina, E.L.; Fernández, E.F.; Carreira, P.; Almorza, T.; Mateos, L.L.; Rodríguez, L.R.; Urgelles, J.F.; Bermejo, P.M.L.; Arrabal, Selene Labrada; Frutos, Anne Rivero|||0000-0002-2981-277X; Pérez, Susana Holgado; Camins, Jordi; Almela, C.M.; Fernández, C.C.; Cid, A.R.; Catalá, J.C.; Melero-González, Rafael|||0000-0002-7967-351X; Maceiras, F.; Pérez, N.; Barbazán, C.; Pego, J.M.; Altabás, I.; Guzman, J.; Alarcón, P.V.E.; Corominas, Hèctor|||0000-0002-7738-6787; Castellvi, Ivan|||0000-0002-5410-5807; Magallares López, Berta|||0000-0002-4691-2342; Millán, A.M.; Villar, M.A.; Cruz Valenciano, A.F.; del Pozo, F.C.; Cambrón, A.B.R.; Villa, C.M.; de Andrés, E.Á.; Mas, A.J.; Vilamajó, I.R.; Barceló, M.I.; Toniolo, Elide|||0000-0002-8327-4861; Cacheda, A.P.; Reyes, M.S.B.; González, M.G.; Dorta, A.G.; Hernández, V.H.; Rocha, M.V.; Allen, J.C.; Uriarte-Ecenarro, M.; Martínez, C.V.; Vicente Rabaneda, E.F.; Porrúa, C.G.; Ubiaga, C.L.I.; Rivas, N.Á.; Rodríguez, T.R.V.; Filloy, J.A.M.; Fernández, A.S.A.; Gonzalez-Gay, MA.|||0000-0002-7924-7406; Galisteo-Lencastre, Carlos|||0000-0003-3619-3185; Villanueva, M.J.G.; Álvarez, P.M.; Cabañas, M.T.; Warleta, M.S.; Vargas, A.P.; Román, A.R.; Cros, C.A.; Jimenez, A.M.; Román Ivorra, J.A.; Bárcena, C.R.; Huaylla, A.; Zorrilla, I.C.; Lluch, Judit|||0000-0002-0804-1355; Valero-Jaimes, J.A.; López Domínguez, L.; Dubuc, Cesar Antonio; Fernández, L.S.

Incidence and clinical manifestations of giant cell arteritis in Spain

This study aimed to estimate the incidence of giant cell arteritis (GCA) in Spain and to analyse its clinical manifestations, and distribution by age group, sex, geographical area and season. Methods We included all patients diagnosed with GCA between 1 June 2013 and 29 March 2019 at 26 hospitals of...

Descripción completa

Detalles Bibliográficos
Autores:	Fernández-Lozano, Delia\|\|\|0000-0001-9650-1296, Hernández-Rodríguez, Iñigo, Narváez, Javier\|\|\|0000-0002-1614-8064, Domínguez-Álvaro, Marta\|\|\|0000-0002-4057-5971, de Miguel, Eugenio\|\|\|0000-0001-5146-1964, Silva-Díaz, Maite\|\|\|0000-0003-1904-011X, Belzunegui, Joaquín María, Morales, Clara Moriano, Sánchez, Julio, Galíndez Agirregoikoa, Eva, Aldaroso, Vicente, Abasolo, Lydia, Loricera, Javier\|\|\|0000-0003-4754-0277, Garrido-Puñal, Noemi, Moya, Patricia\|\|\|0000-0001-8339-5420, Larena, Carmen, Navarro, Vanessa Andrea, Casafont Solé, Ivette\|\|\|0000-0002-1004-300X, Calvet, Joan\|\|\|0000-0002-0888-5152, Ortiz Sanjuán, Francisco, Salman-Monte, Tarek Carlos\|\|\|0000-0002-4676-0174, Castañeda, Santos\|\|\|0000-0002-7748-853X, Blanco, Ricardo\|\|\|0000-0003-2344-2285, Álvarez, E.D., Sandoval, T.P., Fernández, I.G., Mendizábal-Mateos, J., Manteca, M.C.F., del Val del Amo, N., Rubio, L.H., Zudaire, I.P., Courel, L.G., Polo, R.G., Vélez, J.R., Cortina, E.L., Fernández, E.F., Carreira, P., Almorza, T., Mateos, L.L., Rodríguez, L.R., Urgelles, J.F., Bermejo, P.M.L., Arrabal, Selene Labrada, Frutos, Anne Rivero\|\|\|0000-0002-2981-277X, Pérez, Susana Holgado, Camins, Jordi, Almela, C.M., Fernández, C.C., Cid, A.R., Catalá, J.C., Melero-González, Rafael\|\|\|0000-0002-7967-351X, Maceiras, F., Pérez, N., Barbazán, C., Pego, J.M., Altabás, I., Guzman, J., Alarcón, P.V.E., Corominas, Hèctor\|\|\|0000-0002-7738-6787, Castellvi, Ivan\|\|\|0000-0002-5410-5807, Magallares López, Berta\|\|\|0000-0002-4691-2342, Millán, A.M., Villar, M.A., Cruz Valenciano, A.F., del Pozo, F.C., Cambrón, A.B.R., Villa, C.M., de Andrés, E.Á., Mas, A.J., Vilamajó, I.R., Barceló, M.I., Toniolo, Elide\|\|\|0000-0002-8327-4861, Cacheda, A.P., Reyes, M.S.B., González, M.G., Dorta, A.G., Hernández, V.H., Rocha, M.V., Allen, J.C., Uriarte-Ecenarro, M., Martínez, C.V., Vicente Rabaneda, E.F., Porrúa, C.G., Ubiaga, C.L.I., Rivas, N.Á., Rodríguez, T.R.V., Filloy, J.A.M., Fernández, A.S.A., Gonzalez-Gay, MA.\|\|\|0000-0002-7924-7406, Galisteo-Lencastre, Carlos\|\|\|0000-0003-3619-3185, Villanueva, M.J.G., Álvarez, P.M., Cabañas, M.T., Warleta, M.S., Vargas, A.P., Román, A.R., Cros, C.A., Jimenez, A.M., Román Ivorra, J.A., Bárcena, C.R., Huaylla, A., Zorrilla, I.C., Lluch, Judit\|\|\|0000-0002-0804-1355, Valero-Jaimes, J.A., López Domínguez, L., Dubuc, Cesar Antonio, Fernández, L.S.
Tipo de recurso:	artículo
Fecha de publicación:	2024
País:	España
Institución:	Universitat Autònoma de Barcelona
Repositorio:	Dipòsit Digital de Documents de la UAB
Idioma:	inglés
OAI Identifier:	oai:ddd.uab.cat:305611
Acceso en línea:	https://ddd.uab.cat/record/305611 https://dx.doi.org/urn:doi:10.1136/rmdopen-2023-003824
Access Level:	acceso abierto
Palabra clave:	Epidemiology Giant cell arteritis Incidence Vasculitis

id	ES_4bb7aa5b2694ec68a27dadb205619de5
oai_identifier_str	oai:ddd.uab.cat:305611
network_acronym_str	ES
network_name_str	España
repository_id_str
dc.title.none.fl_str_mv	Incidence and clinical manifestations of giant cell arteritis in Spain results of the ARTESER register
title	Incidence and clinical manifestations of giant cell arteritis in Spain
spellingShingle	Incidence and clinical manifestations of giant cell arteritis in Spain Fernández-Lozano, Delia\|\|\|0000-0001-9650-1296 Epidemiology Giant cell arteritis Incidence Vasculitis
title_short	Incidence and clinical manifestations of giant cell arteritis in Spain
title_full	Incidence and clinical manifestations of giant cell arteritis in Spain
title_fullStr	Incidence and clinical manifestations of giant cell arteritis in Spain
title_full_unstemmed	Incidence and clinical manifestations of giant cell arteritis in Spain
title_sort	Incidence and clinical manifestations of giant cell arteritis in Spain
dc.creator.none.fl_str_mv	Fernández-Lozano, Delia\|\|\|0000-0001-9650-1296 Hernández-Rodríguez, Iñigo Narváez, Javier\|\|\|0000-0002-1614-8064 Domínguez-Álvaro, Marta\|\|\|0000-0002-4057-5971 de Miguel, Eugenio\|\|\|0000-0001-5146-1964 Silva-Díaz, Maite\|\|\|0000-0003-1904-011X Belzunegui, Joaquín María Morales, Clara Moriano Sánchez, Julio Galíndez Agirregoikoa, Eva Aldaroso, Vicente Abasolo, Lydia Loricera, Javier\|\|\|0000-0003-4754-0277 Garrido-Puñal, Noemi Moya, Patricia\|\|\|0000-0001-8339-5420 Larena, Carmen Navarro, Vanessa Andrea Casafont Solé, Ivette\|\|\|0000-0002-1004-300X Calvet, Joan\|\|\|0000-0002-0888-5152 Ortiz Sanjuán, Francisco Salman-Monte, Tarek Carlos\|\|\|0000-0002-4676-0174 Castañeda, Santos\|\|\|0000-0002-7748-853X Blanco, Ricardo\|\|\|0000-0003-2344-2285 Álvarez, E.D. Sandoval, T.P. Fernández, I.G. Mendizábal-Mateos, J. Manteca, M.C.F. del Val del Amo, N. Rubio, L.H. Zudaire, I.P. Courel, L.G. Polo, R.G. Vélez, J.R. Cortina, E.L. Fernández, E.F. Carreira, P. Almorza, T. Mateos, L.L. Rodríguez, L.R. Urgelles, J.F. Bermejo, P.M.L. Arrabal, Selene Labrada Frutos, Anne Rivero\|\|\|0000-0002-2981-277X Pérez, Susana Holgado Camins, Jordi Almela, C.M. Fernández, C.C. Cid, A.R. Catalá, J.C. Melero-González, Rafael\|\|\|0000-0002-7967-351X Maceiras, F. Pérez, N. Barbazán, C. Pego, J.M. Altabás, I. Guzman, J. Alarcón, P.V.E. Corominas, Hèctor\|\|\|0000-0002-7738-6787 Castellvi, Ivan\|\|\|0000-0002-5410-5807 Magallares López, Berta\|\|\|0000-0002-4691-2342 Millán, A.M. Villar, M.A. Cruz Valenciano, A.F. del Pozo, F.C. Cambrón, A.B.R. Villa, C.M. de Andrés, E.Á. Mas, A.J. Vilamajó, I.R. Barceló, M.I. Toniolo, Elide\|\|\|0000-0002-8327-4861 Cacheda, A.P. Reyes, M.S.B. González, M.G. Dorta, A.G. Hernández, V.H. Rocha, M.V. Allen, J.C. Uriarte-Ecenarro, M. Martínez, C.V. Vicente Rabaneda, E.F. Porrúa, C.G. Ubiaga, C.L.I. Rivas, N.Á. Rodríguez, T.R.V. Filloy, J.A.M. Fernández, A.S.A. Gonzalez-Gay, MA.\|\|\|0000-0002-7924-7406 Galisteo-Lencastre, Carlos\|\|\|0000-0003-3619-3185 Villanueva, M.J.G. Álvarez, P.M. Cabañas, M.T. Warleta, M.S. Vargas, A.P. Román, A.R. Cros, C.A. Jimenez, A.M. Román Ivorra, J.A. Bárcena, C.R. Huaylla, A. Zorrilla, I.C. Lluch, Judit\|\|\|0000-0002-0804-1355 Valero-Jaimes, J.A. López Domínguez, L. Dubuc, Cesar Antonio Fernández, L.S.
author	Fernández-Lozano, Delia\|\|\|0000-0001-9650-1296
author_facet	Fernández-Lozano, Delia\|\|\|0000-0001-9650-1296 Hernández-Rodríguez, Iñigo Narváez, Javier\|\|\|0000-0002-1614-8064 Domínguez-Álvaro, Marta\|\|\|0000-0002-4057-5971 de Miguel, Eugenio\|\|\|0000-0001-5146-1964 Silva-Díaz, Maite\|\|\|0000-0003-1904-011X Belzunegui, Joaquín María Morales, Clara Moriano Sánchez, Julio Galíndez Agirregoikoa, Eva Aldaroso, Vicente Abasolo, Lydia Loricera, Javier\|\|\|0000-0003-4754-0277 Garrido-Puñal, Noemi Moya, Patricia\|\|\|0000-0001-8339-5420 Larena, Carmen Navarro, Vanessa Andrea Casafont Solé, Ivette\|\|\|0000-0002-1004-300X Calvet, Joan\|\|\|0000-0002-0888-5152 Ortiz Sanjuán, Francisco Salman-Monte, Tarek Carlos\|\|\|0000-0002-4676-0174 Castañeda, Santos\|\|\|0000-0002-7748-853X Blanco, Ricardo\|\|\|0000-0003-2344-2285 Álvarez, E.D. Sandoval, T.P. Fernández, I.G. Mendizábal-Mateos, J. Manteca, M.C.F. del Val del Amo, N. Rubio, L.H. Zudaire, I.P. Courel, L.G. Polo, R.G. Vélez, J.R. Cortina, E.L. Fernández, E.F. Carreira, P. Almorza, T. Mateos, L.L. Rodríguez, L.R. Urgelles, J.F. Bermejo, P.M.L. Arrabal, Selene Labrada Frutos, Anne Rivero\|\|\|0000-0002-2981-277X Pérez, Susana Holgado Camins, Jordi Almela, C.M. Fernández, C.C. Cid, A.R. Catalá, J.C. Melero-González, Rafael\|\|\|0000-0002-7967-351X Maceiras, F. Pérez, N. Barbazán, C. Pego, J.M. Altabás, I. Guzman, J. Alarcón, P.V.E. Corominas, Hèctor\|\|\|0000-0002-7738-6787 Castellvi, Ivan\|\|\|0000-0002-5410-5807 Magallares López, Berta\|\|\|0000-0002-4691-2342 Millán, A.M. Villar, M.A. Cruz Valenciano, A.F. del Pozo, F.C. Cambrón, A.B.R. Villa, C.M. de Andrés, E.Á. Mas, A.J. Vilamajó, I.R. Barceló, M.I. Toniolo, Elide\|\|\|0000-0002-8327-4861 Cacheda, A.P. Reyes, M.S.B. González, M.G. Dorta, A.G. Hernández, V.H. Rocha, M.V. Allen, J.C. Uriarte-Ecenarro, M. Martínez, C.V. Vicente Rabaneda, E.F. Porrúa, C.G. Ubiaga, C.L.I. Rivas, N.Á. Rodríguez, T.R.V. Filloy, J.A.M. Fernández, A.S.A. Gonzalez-Gay, MA.\|\|\|0000-0002-7924-7406 Galisteo-Lencastre, Carlos\|\|\|0000-0003-3619-3185 Villanueva, M.J.G. Álvarez, P.M. Cabañas, M.T. Warleta, M.S. Vargas, A.P. Román, A.R. Cros, C.A. Jimenez, A.M. Román Ivorra, J.A. Bárcena, C.R. Huaylla, A. Zorrilla, I.C. Lluch, Judit\|\|\|0000-0002-0804-1355 Valero-Jaimes, J.A. López Domínguez, L. Dubuc, Cesar Antonio Fernández, L.S.
author_role	author
author2	Hernández-Rodríguez, Iñigo Narváez, Javier\|\|\|0000-0002-1614-8064 Domínguez-Álvaro, Marta\|\|\|0000-0002-4057-5971 de Miguel, Eugenio\|\|\|0000-0001-5146-1964 Silva-Díaz, Maite\|\|\|0000-0003-1904-011X Belzunegui, Joaquín María Morales, Clara Moriano Sánchez, Julio Galíndez Agirregoikoa, Eva Aldaroso, Vicente Abasolo, Lydia Loricera, Javier\|\|\|0000-0003-4754-0277 Garrido-Puñal, Noemi Moya, Patricia\|\|\|0000-0001-8339-5420 Larena, Carmen Navarro, Vanessa Andrea Casafont Solé, Ivette\|\|\|0000-0002-1004-300X Calvet, Joan\|\|\|0000-0002-0888-5152 Ortiz Sanjuán, Francisco Salman-Monte, Tarek Carlos\|\|\|0000-0002-4676-0174 Castañeda, Santos\|\|\|0000-0002-7748-853X Blanco, Ricardo\|\|\|0000-0003-2344-2285 Álvarez, E.D. Sandoval, T.P. Fernández, I.G. Mendizábal-Mateos, J. Manteca, M.C.F. del Val del Amo, N. Rubio, L.H. Zudaire, I.P. Courel, L.G. Polo, R.G. Vélez, J.R. Cortina, E.L. Fernández, E.F. Carreira, P. Almorza, T. Mateos, L.L. Rodríguez, L.R. Urgelles, J.F. Bermejo, P.M.L. Arrabal, Selene Labrada Frutos, Anne Rivero\|\|\|0000-0002-2981-277X Pérez, Susana Holgado Camins, Jordi Almela, C.M. Fernández, C.C. Cid, A.R. Catalá, J.C. Melero-González, Rafael\|\|\|0000-0002-7967-351X Maceiras, F. Pérez, N. Barbazán, C. Pego, J.M. Altabás, I. Guzman, J. Alarcón, P.V.E. Corominas, Hèctor\|\|\|0000-0002-7738-6787 Castellvi, Ivan\|\|\|0000-0002-5410-5807 Magallares López, Berta\|\|\|0000-0002-4691-2342 Millán, A.M. Villar, M.A. Cruz Valenciano, A.F. del Pozo, F.C. Cambrón, A.B.R. Villa, C.M. de Andrés, E.Á. Mas, A.J. Vilamajó, I.R. Barceló, M.I. Toniolo, Elide\|\|\|0000-0002-8327-4861 Cacheda, A.P. Reyes, M.S.B. González, M.G. Dorta, A.G. Hernández, V.H. Rocha, M.V. Allen, J.C. Uriarte-Ecenarro, M. Martínez, C.V. Vicente Rabaneda, E.F. Porrúa, C.G. Ubiaga, C.L.I. Rivas, N.Á. Rodríguez, T.R.V. Filloy, J.A.M. Fernández, A.S.A. Gonzalez-Gay, MA.\|\|\|0000-0002-7924-7406 Galisteo-Lencastre, Carlos\|\|\|0000-0003-3619-3185 Villanueva, M.J.G. Álvarez, P.M. Cabañas, M.T. Warleta, M.S. Vargas, A.P. Román, A.R. Cros, C.A. Jimenez, A.M. Román Ivorra, J.A. Bárcena, C.R. Huaylla, A. Zorrilla, I.C. Lluch, Judit\|\|\|0000-0002-0804-1355 Valero-Jaimes, J.A. López Domínguez, L. Dubuc, Cesar Antonio Fernández, L.S.
author2_role	author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author
dc.contributor.none.fl_str_mv	Universitat Autònoma de Barcelona
dc.subject.none.fl_str_mv	Epidemiology Giant cell arteritis Incidence Vasculitis
topic	Epidemiology Giant cell arteritis Incidence Vasculitis
description	This study aimed to estimate the incidence of giant cell arteritis (GCA) in Spain and to analyse its clinical manifestations, and distribution by age group, sex, geographical area and season. Methods We included all patients diagnosed with GCA between 1 June 2013 and 29 March 2019 at 26 hospitals of the National Health System. They had to be aged ≥50 years and have at least one positive results in an objective diagnostic test (biopsy or imaging techniques), meet 3/5 of the 1990 American College of Rheumatology classification criteria or have a clinical diagnosis based on the expert opinion of the physician in charge. We calculated incidence rate using Poisson regression and assessed the influence of age, sex, geographical area and season. Results We identified 1675 cases of GCA with a mean age at diagnosis of 76.9±8.3 years. The annual incidence was estimated at 7.42 (95% CI 6.57 to 8.27) cases of GCA per 100 000 people ≥50 years with a peak for patients aged 80-84 years (23.06 (95% CI 20.89 to 25.4)). The incidence was greater in women (10.06 (95% CI 8.7 to 11.5)) than in men (4.83 (95% CI 3.8 to 5.9)). No significant differences were found between geographical distribution and incidence throughout the year (p=0.125). The phenotypes at diagnosis were cranial in 1091 patients, extracranial in 337 patients and mixed in 170 patients. Conclusions This is the first study to estimate the incidence of GCA in Spain at a national level. We found a predominance among women and during the ninth decade of life with no clear variability according to geographical area or seasons of the year.
publishDate	2024
dc.date.none.fl_str_mv	2 2024-01-01 2024 2024-01-01
dc.type.none.fl_str_mv	Article http://purl.org/coar/resource_type/c_6501 VoR http://purl.org/coar/version/c_970fb48d4fbd8a85
dc.type.openaire.fl_str_mv	info:eu-repo/semantics/article
format	article
dc.identifier.none.fl_str_mv	https://ddd.uab.cat/record/305611 https://dx.doi.org/urn:doi:10.1136/rmdopen-2023-003824
url	https://ddd.uab.cat/record/305611 https://dx.doi.org/urn:doi:10.1136/rmdopen-2023-003824
dc.language.none.fl_str_mv	Inglés eng
language_invalid_str_mv	Inglés
language	eng
dc.rights.none.fl_str_mv	open access http://purl.org/coar/access_right/c_abf2 https://creativecommons.org/licenses/by-nc/4.0/
dc.rights.openaire.fl_str_mv	info:eu-repo/semantics/openAccess
rights_invalid_str_mv	open access http://purl.org/coar/access_right/c_abf2 https://creativecommons.org/licenses/by-nc/4.0/
eu_rights_str_mv	openAccess
dc.format.none.fl_str_mv	application/pdf
dc.source.none.fl_str_mv	reponame:Dipòsit Digital de Documents de la UAB instname:Universitat Autònoma de Barcelona
instname_str	Universitat Autònoma de Barcelona
reponame_str	Dipòsit Digital de Documents de la UAB
collection	Dipòsit Digital de Documents de la UAB
repository.name.fl_str_mv
repository.mail.fl_str_mv
_version_	1869407580365783040
spelling	Incidence and clinical manifestations of giant cell arteritis in Spainresults of the ARTESER registerFernández-Lozano, Delia\|\|\|0000-0001-9650-1296Hernández-Rodríguez, IñigoNarváez, Javier\|\|\|0000-0002-1614-8064Domínguez-Álvaro, Marta\|\|\|0000-0002-4057-5971de Miguel, Eugenio\|\|\|0000-0001-5146-1964Silva-Díaz, Maite\|\|\|0000-0003-1904-011XBelzunegui, Joaquín MaríaMorales, Clara MorianoSánchez, JulioGalíndez Agirregoikoa, EvaAldaroso, VicenteAbasolo, LydiaLoricera, Javier\|\|\|0000-0003-4754-0277Garrido-Puñal, NoemiMoya, Patricia\|\|\|0000-0001-8339-5420Larena, CarmenNavarro, Vanessa AndreaCasafont Solé, Ivette\|\|\|0000-0002-1004-300XCalvet, Joan\|\|\|0000-0002-0888-5152Ortiz Sanjuán, FranciscoSalman-Monte, Tarek Carlos\|\|\|0000-0002-4676-0174Castañeda, Santos\|\|\|0000-0002-7748-853XBlanco, Ricardo\|\|\|0000-0003-2344-2285Álvarez, E.D.Sandoval, T.P.Fernández, I.G.Mendizábal-Mateos, J.Manteca, M.C.F.del Val del Amo, N.Rubio, L.H.Zudaire, I.P.Courel, L.G.Polo, R.G.Vélez, J.R.Cortina, E.L.Fernández, E.F.Carreira, P.Almorza, T.Mateos, L.L.Rodríguez, L.R.Urgelles, J.F.Bermejo, P.M.L.Arrabal, Selene LabradaFrutos, Anne Rivero\|\|\|0000-0002-2981-277XPérez, Susana HolgadoCamins, JordiAlmela, C.M.Fernández, C.C.Cid, A.R.Catalá, J.C.Melero-González, Rafael\|\|\|0000-0002-7967-351XMaceiras, F.Pérez, N.Barbazán, C.Pego, J.M.Altabás, I.Guzman, J.Alarcón, P.V.E.Corominas, Hèctor\|\|\|0000-0002-7738-6787Castellvi, Ivan\|\|\|0000-0002-5410-5807Magallares López, Berta\|\|\|0000-0002-4691-2342Millán, A.M.Villar, M.A.Cruz Valenciano, A.F.del Pozo, F.C.Cambrón, A.B.R.Villa, C.M.de Andrés, E.Á.Mas, A.J.Vilamajó, I.R.Barceló, M.I.Toniolo, Elide\|\|\|0000-0002-8327-4861Cacheda, A.P.Reyes, M.S.B.González, M.G.Dorta, A.G.Hernández, V.H.Rocha, M.V.Allen, J.C.Uriarte-Ecenarro, M.Martínez, C.V.Vicente Rabaneda, E.F.Porrúa, C.G.Ubiaga, C.L.I.Rivas, N.Á.Rodríguez, T.R.V.Filloy, J.A.M.Fernández, A.S.A.Gonzalez-Gay, MA.\|\|\|0000-0002-7924-7406Galisteo-Lencastre, Carlos\|\|\|0000-0003-3619-3185Villanueva, M.J.G.Álvarez, P.M.Cabañas, M.T.Warleta, M.S.Vargas, A.P.Román, A.R.Cros, C.A.Jimenez, A.M.Román Ivorra, J.A.Bárcena, C.R.Huaylla, A.Zorrilla, I.C.Lluch, Judit\|\|\|0000-0002-0804-1355Valero-Jaimes, J.A.López Domínguez, L.Dubuc, Cesar AntonioFernández, L.S.EpidemiologyGiant cell arteritisIncidenceVasculitisThis study aimed to estimate the incidence of giant cell arteritis (GCA) in Spain and to analyse its clinical manifestations, and distribution by age group, sex, geographical area and season. Methods We included all patients diagnosed with GCA between 1 June 2013 and 29 March 2019 at 26 hospitals of the National Health System. They had to be aged ≥50 years and have at least one positive results in an objective diagnostic test (biopsy or imaging techniques), meet 3/5 of the 1990 American College of Rheumatology classification criteria or have a clinical diagnosis based on the expert opinion of the physician in charge. We calculated incidence rate using Poisson regression and assessed the influence of age, sex, geographical area and season. Results We identified 1675 cases of GCA with a mean age at diagnosis of 76.9±8.3 years. The annual incidence was estimated at 7.42 (95% CI 6.57 to 8.27) cases of GCA per 100 000 people ≥50 years with a peak for patients aged 80-84 years (23.06 (95% CI 20.89 to 25.4)). The incidence was greater in women (10.06 (95% CI 8.7 to 11.5)) than in men (4.83 (95% CI 3.8 to 5.9)). No significant differences were found between geographical distribution and incidence throughout the year (p=0.125). The phenotypes at diagnosis were cranial in 1091 patients, extracranial in 337 patients and mixed in 170 patients. Conclusions This is the first study to estimate the incidence of GCA in Spain at a national level. We found a predominance among women and during the ninth decade of life with no clear variability according to geographical area or seasons of the year.Universitat Autònoma de Barcelona 22024-01-0120242024-01-01Articlehttp://purl.org/coar/resource_type/c_6501VoRhttp://purl.org/coar/version/c_970fb48d4fbd8a85info:eu-repo/semantics/articleapplication/pdfhttps://ddd.uab.cat/record/305611https://dx.doi.org/urn:doi:10.1136/rmdopen-2023-003824reponame:Dipòsit Digital de Documents de la UABinstname:Universitat Autònoma de BarcelonaInglésengopen accesshttp://purl.org/coar/access_right/c_abf2Aquest document està subjecte a una llicència d'ús Creative Commons. Es permet la reproducció total o parcial, la distribució, la comunicació pública de l'obra i la creació d'obres derivades, sempre que no sigui amb finalitats comercials, i sempre que es reconegui l'autoria de l'obra original.https://creativecommons.org/licenses/by-nc/4.0/info:eu-repo/semantics/openAccessoai:ddd.uab.cat:3056112026-06-06T12:50:31Z
score	15,198674

Incidence and clinical manifestations of giant cell arteritis in Spain

Similares en LA Referencia