Toward Sub-100 ps TOF-PET Systems Employing the FastIC ASIC With Analog SiPMs

Time of Flight positron emission tomography (TOFPET) scanners demand electronics that are power-efficient, low-noise, cost-effective, and possess a large bandwidth. Recent developments have demonstrated sub-100 ps time resolution with elevated power consumption per channel, rendering this unfeasible...

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Bibliographic Details
Authors: Mariscal-Castilla, Antonio, Gomez Fernandez, Sergio, Manera Escalero, Rafel, Fernandez-Tenllado, José María, Mauricio Ferre, Joan, Kratochwil, Nicolaus, Alozy, J., Piller, Markus, Portero, Sara, Sanuy Charles, Andreu, Guberman, Daniel Alberto, Silva, J. J., Auffray, Etiennette, Ballabriga, Rafael, Ariño Estrada, Gerard, Campbell, Michael, Gascón Fora, David
Format: article
Status:Published version
Publication Date:2024
Country:España
Institution:Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)
Repository:Recercat. Dipósit de la Recerca de Catalunya
OAI Identifier:oai:recercat.cat:2445/222115
Online Access:https://hdl.handle.net/2445/222115
Access Level:Open access
Keyword:Tomografia per emissió de positrons
Sistemes d'imatges
Positron emission tomography
Imaging systems
Description
Summary:Time of Flight positron emission tomography (TOFPET) scanners demand electronics that are power-efficient, low-noise, cost-effective, and possess a large bandwidth. Recent developments have demonstrated sub-100 ps time resolution with elevated power consumption per channel, rendering this unfeasible to build a scanner. In this work, we evaluate the performance for the TOF-PET of the FastIC front-end using different scintillators and silicon photomultipliers (SiPMs). FastIC is an eight-channel application specific integrated circuit developed in CMOS 65 nm capable of measuring the energy and the arrival time of a detected pulse with 12 mW per channel. Using Hamamatsu SiPMs (S13360-3050PE) coupled to LSO:Ce:0.2%Ca crystals of 2 × 2 × 3 mm3 and LYSO:Ce:0.2%Ca of 3.13 × 3.13 × 20 mm3, we measured a coincidence time resolution (CTR) of (95 ± 3) and 156 ± 4) ps full width half maximum (FWHM), respectively. With Fondazione Bruno Kessler NUV-HD LF2 M0 SiPMs coupled to the same crystals, we obtained a CTR of (76 ± 2) and (127 ± 3) ps FWHM. We employed FastIC with a TlCl pure Cherenkov emitter, demonstrating time resolutions comparable to those achieved with the high-power-consuming electronics. These findings shows that the FastIC represents a cost-effective alternative that can significantly enhance the time resolution of the current TOF-PET systems while maintaining low power consumption. Index Terms—Fast front-end electronics, photo-detector technology, positron emission tomography, scintillator, silicon photomultipliers (SiPMs), Time of Flight positron emission tomography (TOF-PET).

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