Exploiting the accumulated evidence for gene selection in microarray gene expression data
Machine Learning methods have of late made signicant efforts to solving multidisciplinary problems in the field of cancer classification using microarray gene expression data. Feature subset selection methods can play an important role in the modeling process, since these tasks are characterized by...
| Autores: | , |
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| Formato: | informe técnico |
| Fecha de publicación: | 2013 |
| País: | España |
| Recursos: | Universitat Politècnica de Catalunya (UPC) |
| Repositorio: | UPCommons. Portal del coneixement obert de la UPC |
| Idioma: | inglés |
| OAI Identifier: | oai:upcommons.upc.edu:2117/99401 |
| Acesso em linha: | https://hdl.handle.net/2117/99401 |
| Access Level: | acceso abierto |
| Palavra-chave: | Cancer classification Microarray gene expression data Àrees temàtiques de la UPC::Informàtica::Informàtica teòrica |
| Resumo: | Machine Learning methods have of late made signicant efforts to solving multidisciplinary problems in the field of cancer classification using microarray gene expression data. Feature subset selection methods can play an important role in the modeling process, since these tasks are characterized by a large number of features and a few observations, making the modeling a non-trivial undertaking. In this particular scenario, it is extremely important to select genes by taking into account the possible interactions with other gene subsets. This paper shows that, by accumulating the evidence in favour (or against) each gene along the search process, the obtained gene subsets may constitute better solutions, either in terms of predictive accuracy or gene size, or in both. The proposed technique is extremely simple and applicable at a negligible overhead in cost. |
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