Microplastic residues in clinical samples: A retrospection on sources, entry routes, detection methods and human toxicity

Microplastics (MPs) are emerging toxicants which have been detected in varying environments. Despite MPs adverse effects, reports on MPs detection from human clinical samples are only a few. This is due to several reasons such as inefficiency of current MPs detection techniques to detect them from h...

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Detalles Bibliográficos
Autores: Sharma, Neha, Kumar, Vinay, Vimal, S., Umesh, Mridul, Chakraborty, Pritha, Basheer, Thazeem, Sarojini, Suma, Sharma, Preeti, Pasrija, Ritu, Barceló, Damià
Tipo de recurso: artículo
Estado:Versión aceptada para publicación
Fecha de publicación:2024
País:España
Institución:Consejo Superior de Investigaciones Científicas (CSIC)
Repositorio:DIGITAL.CSIC. Repositorio Institucional del CSIC
OAI Identifier:oai:digital.csic.es:10261/379446
Acceso en línea:http://hdl.handle.net/10261/379446
https://api.elsevier.com/content/abstract/scopus_id/85187793038
Access Level:acceso abierto
Palabra clave:Toxicity
Analytical methods
Clinical samples
Human organ
Human samples
Microplastics
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Ensure healthy lives and promote well-being for all at all ages
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Descripción
Sumario:Microplastics (MPs) are emerging toxicants which have been detected in varying environments. Despite MPs adverse effects, reports on MPs detection from human clinical samples are only a few. This is due to several reasons such as inefficiency of current MPs detection techniques to detect them from human clinical samples, lack of understanding about the MPs toxicity to human organs and ethical regulations that restricts study with human placental exposure to MPs. This review gives a comprehensive outlook on the major sources MPs sources and routes into human system and their human toxicity mechanisms. Further an in-depth discussion on the significance and limitations of various MPs detection methods is elaborated in the review. Challenges in current research framework for detection of MPs from human clinical samples and the possible future directions in this imperative research domain are also focused in this review.