Accuracy of verbal fluency tests in the discrimination of mild cognitive impairment and probable Alzheimer's disease in older Spanish monolingual individuals
The main objetive was to analyze the accuracy of different verbal fluency tests (VFTs) in discriminating cognitively healthy subjects from individuals with mild cognitive impairment (MCI) and probable Alzheimer’s disease (AD) in a cohort of older Spanish speaking adults. As a result, we aimed to ide...
| Autores: | , , , |
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| Tipo de documento: | artigo |
| Data de publicação: | 2019 |
| País: | España |
| Recursos: | Universidad Nacional de Educación a Distancia |
| Repositório: | e-spacio. Repositorio Institucional de la UNED |
| Idioma: | inglês |
| OAI Identifier: | oai:e-spacio.uned.es:20.500.14468/25047 |
| Acesso em linha: | https://hdl.handle.net/20.500.14468/25047 |
| Access Level: | Acceso aberto |
| Palavra-chave: | 61 Psicología Animal fluency test alzheimer’s disease cut-off scores mild cognitive impairment verbal fluency |
| Resumo: | The main objetive was to analyze the accuracy of different verbal fluency tests (VFTs) in discriminating cognitively healthy subjects from individuals with mild cognitive impairment (MCI) and probable Alzheimer’s disease (AD) in a cohort of older Spanish speaking adults. As a result, we aimed to identify the VFT that best predicts conversion from MCI to probable AD. 287 subjects: 170 controls (HC), 90 stable MCI and 27 patients with MCI that evolved into probable AD (MCI-AD) were assessed with a neuropsychological battery test and five VFTs. The animal fluency test produced the best differentiation of HC from MCI (p < .001), of HC from MCI-AD (p < .001) and of MCI from MCI-AD converters (p < .001), with sensitivities 98.8%, 98.8% and 75.6%, respectively. Logistic regression showed that the animal fluency test (p < 0.001) appears to be the most useful and neuropsychological VFT to predict conversion to probable dementia. |
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