Influenza vaccine effectiveness in preventing hospitalisation of individuals 60 years of age and over with laboratory-confirmed influenza, Valencia Region, Spain, influenza season 2016/17

Research article Influenza vaccine effectiveness in preventing hospitalisation of individuals 60 years of age and over with laboratory-confirmed influenza, Valencia Region, Spain, influenza season 2016/17 Ainara Mira-Iglesias¹, F Xavier López-Labrador 1,2 , Beatriz Guglieri-López¹, Miguel Tortajada-...

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Autores: Mira Iglesias, A., López Labrador, F.X., Guglieri López, Beatriz, Tortajada Girbés, Miguel, Baselga Moreno, V., Cano, Laura, Mollar Maseres, Juan, Carballido Fernández, Mario, Schwarz Chavarri, Germán, Díez Domingo, Javier, Puig Barberà, Joan
Formato: artículo
Fecha de publicación:2018
País:España
Recursos:Universidad Católica de Valencia San Vicente Mártir
Repositorio:RIUCV. Repositorio de la Universidad Católica de Valencia San Vicente Mártir
Idioma:inglés
OAI Identifier:oai:riucv.ucv.es:20.500.12466/3269
Acesso em linha:http://hdl.handle.net/20.500.12466/3269
Access Level:acceso abierto
Palavra-chave:Vaccination
Respiratory Viruses Disease (VAHNSI)
Patients vaccinated
3201.04 Patología Clínica
32 Ciencias Médicas
2412.10 Vacunas
3205.05 Enfermedades Infecciosas
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oai_identifier_str oai:riucv.ucv.es:20.500.12466/3269
network_acronym_str ES
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repository_id_str
dc.title.none.fl_str_mv Influenza vaccine effectiveness in preventing hospitalisation of individuals 60 years of age and over with laboratory-confirmed influenza, Valencia Region, Spain, influenza season 2016/17
title Influenza vaccine effectiveness in preventing hospitalisation of individuals 60 years of age and over with laboratory-confirmed influenza, Valencia Region, Spain, influenza season 2016/17
spellingShingle Influenza vaccine effectiveness in preventing hospitalisation of individuals 60 years of age and over with laboratory-confirmed influenza, Valencia Region, Spain, influenza season 2016/17
Mira Iglesias, A.
Vaccination
Respiratory Viruses Disease (VAHNSI)
Patients vaccinated
3201.04 Patología Clínica
32 Ciencias Médicas
2412.10 Vacunas
3205.05 Enfermedades Infecciosas
title_short Influenza vaccine effectiveness in preventing hospitalisation of individuals 60 years of age and over with laboratory-confirmed influenza, Valencia Region, Spain, influenza season 2016/17
title_full Influenza vaccine effectiveness in preventing hospitalisation of individuals 60 years of age and over with laboratory-confirmed influenza, Valencia Region, Spain, influenza season 2016/17
title_fullStr Influenza vaccine effectiveness in preventing hospitalisation of individuals 60 years of age and over with laboratory-confirmed influenza, Valencia Region, Spain, influenza season 2016/17
title_full_unstemmed Influenza vaccine effectiveness in preventing hospitalisation of individuals 60 years of age and over with laboratory-confirmed influenza, Valencia Region, Spain, influenza season 2016/17
title_sort Influenza vaccine effectiveness in preventing hospitalisation of individuals 60 years of age and over with laboratory-confirmed influenza, Valencia Region, Spain, influenza season 2016/17
dc.creator.none.fl_str_mv Mira Iglesias, A.
López Labrador, F.X.
Guglieri López, Beatriz
Tortajada Girbés, Miguel
Baselga Moreno, V.
Cano, Laura
Mollar Maseres, Juan
Carballido Fernández, Mario
Schwarz Chavarri, Germán
Díez Domingo, Javier
Puig Barberà, Joan
author Mira Iglesias, A.
author_facet Mira Iglesias, A.
López Labrador, F.X.
Guglieri López, Beatriz
Tortajada Girbés, Miguel
Baselga Moreno, V.
Cano, Laura
Mollar Maseres, Juan
Carballido Fernández, Mario
Schwarz Chavarri, Germán
Díez Domingo, Javier
Puig Barberà, Joan
author_role author
author2 López Labrador, F.X.
Guglieri López, Beatriz
Tortajada Girbés, Miguel
Baselga Moreno, V.
Cano, Laura
Mollar Maseres, Juan
Carballido Fernández, Mario
Schwarz Chavarri, Germán
Díez Domingo, Javier
Puig Barberà, Joan
author2_role author
author
author
author
author
author
author
author
author
author
dc.contributor.none.fl_str_mv
dc.subject.none.fl_str_mv Vaccination
Respiratory Viruses Disease (VAHNSI)
Patients vaccinated
3201.04 Patología Clínica
32 Ciencias Médicas
2412.10 Vacunas
3205.05 Enfermedades Infecciosas
topic Vaccination
Respiratory Viruses Disease (VAHNSI)
Patients vaccinated
3201.04 Patología Clínica
32 Ciencias Médicas
2412.10 Vacunas
3205.05 Enfermedades Infecciosas
description Research article Influenza vaccine effectiveness in preventing hospitalisation of individuals 60 years of age and over with laboratory-confirmed influenza, Valencia Region, Spain, influenza season 2016/17 Ainara Mira-Iglesias¹, F Xavier López-Labrador 1,2 , Beatriz Guglieri-López¹, Miguel Tortajada-Girbés³, Víctor Baselga-Moreno¹, Laura Cano¹, Juan Mollar-Maseres⁴, Mario Carballido-Fernández5,6 , Germán Schwarz-Chavarri⁷, Javier Díez-Domingo¹, Joan Puig- Barberà 1,8 , Valencia Hospital Network for the Study of Influenza and Respiratory Viruses Disease 1 1. Fundación para el Fomento de la Investigación Sanitaria y Biomédica de la Comunitat Valenciana (FISABIO-Public Health), Valencia, Spain 2. Consorcio de Investigación Biomédica de Epidemiología y Salud Pública (CIBERESP), Instituto de Salud Carlos III, Madrid, Spain 3. Hospital Doctor Peset, Valencia, Spain 4. Hospital Universitario y Politécnico La Fe, Valencia, Spain 5. Hospital General Universitario de Castellón, Castellón, Spain 6. Universidad CEU Cardenal Herrera, Castellón, Spain 7. Hospital General de Alicante, Alicante, Spain 8. Centro de Salud Pública de Castellón, Castellón, Spain Correspondence: Joan Puig-Barbera (jpuigb55@gmail.com) Citation style for this article: Mira-Iglesias Ainara, López-Labrador F Xavier, Guglieri-López Beatriz, Tortajada-Girbés Miguel, Baselga-Moreno Víctor, Cano Laura, Mollar-Maseres Juan, Carballido-Fernández Mario, Schwarz-Chavarri Germán, Díez-Domingo Javier, Puig-Barberà Joan, Valencia Hospital Network for the Study of Influenza and Respiratory Viruses Disease. Influenza vaccine effectiveness in preventing hospitalisation of individuals 60 years of age and over with laboratory-confirmed influenza, Valencia Region, Spain, influenza season 2016/17. Euro Surveill. 2018;23(8):pii=17-00318. https://doi.org/10.2807/1560-7917.ES.2018.23.8.17-00318 Article submitted on 07 May 2017 / accepted on 01 Sep 2017 / published on 22 February 2018 Introduction: Seasonal influenza vaccination is widely recommended for people with risk factors, especially for people who are elderly. However, influenza vac- cine effectiveness (IVE) varies year after year because of the variable antigenic composition of the circulat- ing viruses and the vaccine composition. Methods: We summarise the results of IVE and the impact of pre- vious vaccination among subjects 60 years of age and over in a multicentre prospective study in the Valencia Hospital Surveillance Network for the Study of Influenza and Respiratory Viruses Disease (VAHNSI) in Spain. We applied the test-negative design taking laboratory-confirmed influenza as outcome and vacci- nation status as exposure. Information about potential confounders was obtained from clinical registries or directly from patients. Results: Adjusted IVE was 19% (95% confidence interval (CI): −15 to 43). For patients vaccinated in the current season but not in the two pre- vious seasons, effectiveness was 49% (95% CI: −20 to 78) and for patients vaccinated in the current and any of two previous seasons, effectiveness was 29% (95% CI: −3 to 52). For those patients not vaccinated in the current season but vaccinated in any of the two pre- vious seasons, effectiveness was 53% (95% CI: 8 to 76). Conclusions: Our data show a low vaccine effec- tiveness for the 2016/17 influenza season
publishDate 2018
dc.date.none.fl_str_mv 2018
2018-02-22
2018
2018-02-22
2023
2023-12-12
dc.type.none.fl_str_mv journal article
http://purl.org/coar/resource_type/c_6501
dc.type.openaire.fl_str_mv info:eu-repo/semantics/article
format article
dc.identifier.none.fl_str_mv http://hdl.handle.net/20.500.12466/3269
url http://hdl.handle.net/20.500.12466/3269
dc.language.none.fl_str_mv Inglés
eng
language_invalid_str_mv Inglés
language eng
dc.rights.none.fl_str_mv open access
http://purl.org/coar/access_right/c_abf2
Atribución 4.0 Internacional
http://creativecommons.org/licenses/by/4.0/
dc.rights.openaire.fl_str_mv info:eu-repo/semantics/openAccess
rights_invalid_str_mv open access
http://purl.org/coar/access_right/c_abf2
Atribución 4.0 Internacional
http://creativecommons.org/licenses/by/4.0/
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.source.none.fl_str_mv reponame:RIUCV. Repositorio de la Universidad Católica de Valencia San Vicente Mártir
instname:Universidad Católica de Valencia San Vicente Mártir
instname_str Universidad Católica de Valencia San Vicente Mártir
reponame_str RIUCV. Repositorio de la Universidad Católica de Valencia San Vicente Mártir
collection RIUCV. Repositorio de la Universidad Católica de Valencia San Vicente Mártir
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spelling Influenza vaccine effectiveness in preventing hospitalisation of individuals 60 years of age and over with laboratory-confirmed influenza, Valencia Region, Spain, influenza season 2016/17Mira Iglesias, A.López Labrador, F.X.Guglieri López, BeatrizTortajada Girbés, MiguelBaselga Moreno, V.Cano, LauraMollar Maseres, JuanCarballido Fernández, MarioSchwarz Chavarri, GermánDíez Domingo, JavierPuig Barberà, JoanVaccinationRespiratory Viruses Disease (VAHNSI)Patients vaccinated3201.04 Patología Clínica32 Ciencias Médicas2412.10 Vacunas3205.05 Enfermedades InfecciosasResearch article Influenza vaccine effectiveness in preventing hospitalisation of individuals 60 years of age and over with laboratory-confirmed influenza, Valencia Region, Spain, influenza season 2016/17 Ainara Mira-Iglesias¹, F Xavier López-Labrador 1,2 , Beatriz Guglieri-López¹, Miguel Tortajada-Girbés³, Víctor Baselga-Moreno¹, Laura Cano¹, Juan Mollar-Maseres⁴, Mario Carballido-Fernández5,6 , Germán Schwarz-Chavarri⁷, Javier Díez-Domingo¹, Joan Puig- Barberà 1,8 , Valencia Hospital Network for the Study of Influenza and Respiratory Viruses Disease 1 1. Fundación para el Fomento de la Investigación Sanitaria y Biomédica de la Comunitat Valenciana (FISABIO-Public Health), Valencia, Spain 2. Consorcio de Investigación Biomédica de Epidemiología y Salud Pública (CIBERESP), Instituto de Salud Carlos III, Madrid, Spain 3. Hospital Doctor Peset, Valencia, Spain 4. Hospital Universitario y Politécnico La Fe, Valencia, Spain 5. Hospital General Universitario de Castellón, Castellón, Spain 6. Universidad CEU Cardenal Herrera, Castellón, Spain 7. Hospital General de Alicante, Alicante, Spain 8. Centro de Salud Pública de Castellón, Castellón, Spain Correspondence: Joan Puig-Barbera (jpuigb55@gmail.com) Citation style for this article: Mira-Iglesias Ainara, López-Labrador F Xavier, Guglieri-López Beatriz, Tortajada-Girbés Miguel, Baselga-Moreno Víctor, Cano Laura, Mollar-Maseres Juan, Carballido-Fernández Mario, Schwarz-Chavarri Germán, Díez-Domingo Javier, Puig-Barberà Joan, Valencia Hospital Network for the Study of Influenza and Respiratory Viruses Disease. Influenza vaccine effectiveness in preventing hospitalisation of individuals 60 years of age and over with laboratory-confirmed influenza, Valencia Region, Spain, influenza season 2016/17. Euro Surveill. 2018;23(8):pii=17-00318. https://doi.org/10.2807/1560-7917.ES.2018.23.8.17-00318 Article submitted on 07 May 2017 / accepted on 01 Sep 2017 / published on 22 February 2018 Introduction: Seasonal influenza vaccination is widely recommended for people with risk factors, especially for people who are elderly. However, influenza vac- cine effectiveness (IVE) varies year after year because of the variable antigenic composition of the circulat- ing viruses and the vaccine composition. Methods: We summarise the results of IVE and the impact of pre- vious vaccination among subjects 60 years of age and over in a multicentre prospective study in the Valencia Hospital Surveillance Network for the Study of Influenza and Respiratory Viruses Disease (VAHNSI) in Spain. We applied the test-negative design taking laboratory-confirmed influenza as outcome and vacci- nation status as exposure. Information about potential confounders was obtained from clinical registries or directly from patients. Results: Adjusted IVE was 19% (95% confidence interval (CI): −15 to 43). For patients vaccinated in the current season but not in the two pre- vious seasons, effectiveness was 49% (95% CI: −20 to 78) and for patients vaccinated in the current and any of two previous seasons, effectiveness was 29% (95% CI: −3 to 52). For those patients not vaccinated in the current season but vaccinated in any of the two pre- vious seasons, effectiveness was 53% (95% CI: 8 to 76). Conclusions: Our data show a low vaccine effec- tiveness for the 2016/17 influenza season20232023-12-1220182018-02-2220182018-02-22journal articlehttp://purl.org/coar/resource_type/c_6501info:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/20.500.12466/3269reponame:RIUCV. Repositorio de la Universidad Católica de Valencia San Vicente Mártirinstname:Universidad Católica de Valencia San Vicente MártirInglésengopen accesshttp://purl.org/coar/access_right/c_abf2Atribución 4.0 Internacionalhttp://creativecommons.org/licenses/by/4.0/info:eu-repo/semantics/openAccessoai:riucv.ucv.es:20.500.12466/32692026-06-19T08:32:07Z
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