Modeling a processive molecular motor: the conventional kinesin

We present a model that allows for the derivation of the experimentally accesible observables: spatial steps, mean velocity, stall force, useful power, efficiency and randomness, etc. as a function of the [adenosine triphosphate] concentration and an external load F. The model presents a minimum of...

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Detalhes bibliográficos
Autores: Ciudad Álvarez, Aleix, Lacasta Palacio, Ana María, Sancho, José M.
Formato: artículo
Estado:Versión publicada
Fecha de publicación:2005
País:España
Recursos:Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)
Repositorio:Recercat. Dipósit de la Recerca de Catalunya
OAI Identifier:oai:recercat.cat:2445/18720
Acesso em linha:https://hdl.handle.net/2445/18720
Access Level:acceso abierto
Palavra-chave:Biofísica
Física mèdica
Física estadística
Termodinàmica
Sistemes dinàmics diferenciables
Biophysics
Medical physics
Statistical physics
Thermodynamics
Differentiable dynamical systems
Descrição
Resumo:We present a model that allows for the derivation of the experimentally accesible observables: spatial steps, mean velocity, stall force, useful power, efficiency and randomness, etc. as a function of the [adenosine triphosphate] concentration and an external load F. The model presents a minimum of adjustable parameters and the theoretical predictions compare well with the available experimental results.