The relevance of biomaterials to the prevention and treatment of osteoporosis

Osteoporosis is a worldwide disease with a very high prevalence in humans older than 50. The main clinical consequences are bone fractures, which often lead to patient disability or even death. A number of commercial biomaterials are currently used to treat osteoporotic bone fractures, but most of t...

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Detalhes bibliográficos
Autores: Arcos Navarrete, Daniel, Boccaccini, A. R., Bohner, M., Díez Pérez, A., Epple, M., Gómez Barrena, E., Herrera, A., Planell, J. A., Rodríguez Manas, L., Vallet Regí, María Dulce Nombre
Tipo de documento: artigo
Data de publicação:2014
País:España
Recursos:Universidad Complutense de Madrid (UCM)
Repositório:Docta Complutense
Idioma:inglês
OAI Identifier:oai:docta.ucm.es:20.500.14352/35363
Acesso em linha:https://hdl.handle.net/20.500.14352/35363
Access Level:Acceso aberto
Palavra-chave:546
615.46
Osteoporosis
Biomaterials
Ageing
Bone
Materiales
Química inorgánica (Química)
3312 Tecnología de Materiales
2303 Química Inorgánica
Descrição
Resumo:Osteoporosis is a worldwide disease with a very high prevalence in humans older than 50. The main clinical consequences are bone fractures, which often lead to patient disability or even death. A number of commercial biomaterials are currently used to treat osteoporotic bone fractures, but most of these have not been specifically designed for that purpose. Many drug- or cell-loaded biomaterials have been proposed in research laboratories, but very few have received approval for commercial use. In order to analyze this scenario and propose alternatives to overcome it, the Spanish and European Network of Excellence for the Prevention and Treatment of Osteoporotic Fractures, ‘‘Ageing’’, was created. This network integrates three communities, e.g. clinicians, materials scientists and industrial advisors, tackling the same problem from three different points of view. Keeping in mind the premise ‘‘living longer, living better’’, this commentary is the result of the thoughts, proposals and conclusions obtained after one year working in the framework of this network.