Disentangling tau and brain atrophy cluster heterogeneity across the Alzheimer's disease continuum

[Introduction] Neuroimaging heterogeneity in dementia has been examined using single modalities. We evaluated the associations of magnetic resonance imaging (MRI) atrophy and flortaucipir positron emission tomography (PET) clusters across the Alzheimer's disease (AD) spectrum.

Detalhes bibliográficos
Autores: Toledo, Jon B., Liu, Hangfan, Grothe, Michel J., Rashid, Tanweer, Launer, Lenore, Shaw, Leslie M., Snoussi, Haykel, Heckbert, Susan, Weiner, Michael, Trojanwoski, John Q., Seshadri, Sudha, Habes, Mohamad
Formato: artículo
Estado:Versión publicada
Fecha de publicación:2022
País:España
Recursos:Consejo Superior de Investigaciones Científicas (CSIC)
Repositorio:DIGITAL.CSIC. Repositorio Institucional del CSIC
OAI Identifier:oai:digital.csic.es:10261/305454
Acesso em linha:http://hdl.handle.net/10261/305454
https://api.elsevier.com/content/abstract/scopus_id/85138700262
Access Level:acceso abierto
Palavra-chave:Alzheimer's disease
Amyloid beta
Heterogeneity
Mangetic resonance imaging
Positron emission tomography
Prognosis
Tau
Descrição
Resumo:[Introduction] Neuroimaging heterogeneity in dementia has been examined using single modalities. We evaluated the associations of magnetic resonance imaging (MRI) atrophy and flortaucipir positron emission tomography (PET) clusters across the Alzheimer's disease (AD) spectrum.