In Situ Assembly of a Metal-Templated Catalyst for Asymmetric Aldol Reactions: From the Metal Complexes Equilibria to a Practical System

A zinc(II)-templated catalyst assembling terpyridine and bipyridine organocatalytic ligands has been developed for the asymmetric aldol reaction. The system has been optimized to maximize the formation of the heteromeric bifunctional species through the determination of the equilibrium constants lea...

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Detalles Bibliográficos
Autores: Jimeno, Ciril, Solà, Jordi, Alfonso, Ignacio
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2024
País:España
Institución:Consejo Superior de Investigaciones Científicas (CSIC)
Repositorio:DIGITAL.CSIC. Repositorio Institucional del CSIC
OAI Identifier:oai:digital.csic.es:10261/345283
Acceso en línea:http://hdl.handle.net/10261/345283
https://api.elsevier.com/content/abstract/scopus_id/85183020731
Access Level:acceso abierto
Palabra clave:Terpyridine
Aldol reaction
Asymmetric catalysis
Metal-templated-catalysis
Self-asssembly
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Descripción
Sumario:A zinc(II)-templated catalyst assembling terpyridine and bipyridine organocatalytic ligands has been developed for the asymmetric aldol reaction. The system has been optimized to maximize the formation of the heteromeric bifunctional species through the determination of the equilibrium constants leading to the formation of all the species present. A practical, easy to synthesize catalytic system providing high stereoselectivity has been achieved in this way.