The implementation of a streamlined TAVI patient pathway across five European countries: BENCHMARK registry.
Background: Benchmark best practices have been shown to streamline the clinical pathway for patients undergoing transcatheter aortic valve implantation (TAVI), but the impact in diverse health systems is unknown. Aims: We evaluated the impact of Benchmark best practices implementation in Germany, Au...
| Autores: | , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , |
|---|---|
| Tipo de recurso: | artículo |
| Fecha de publicación: | 2025 |
| País: | España |
| Institución: | Conselleria de Salut i Consum del Govern de les Illes Balears |
| Repositorio: | Docusalut |
| Idioma: | inglés |
| OAI Identifier: | oai:docusalut.com:20.500.13003/24965 |
| Acceso en línea: | https://hdl.handle.net/20.500.13003/24965 |
| Access Level: | acceso abierto |
| Palabra clave: | Aortic Valve Stenosis Quality of Health Care Transcatheter Aortic Valve Replacement Estenosis de la Válvula Aórtica Calidad de la Atención de Salud Reemplazo de la Válvula Aórtica Transcatéter Aortic stenosis Clinical care Prospective registry Quality of care TAVI Transcatheter aortic valve implantation |
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The implementation of a streamlined TAVI patient pathway across five European countries: BENCHMARK registry.Saia, Francesco.Lauck, SandraDurand, EricMuir, Douglas FSpence, MarkVasa-Nicotera, MariucaWood, DavidUrbano-Carrillo, Cristóbal ABouchayer, DamienIliescu, Vlad AntonEtienne, Christophe SaintLeclercq, FlorenceAuffret, VincentAsmarats, LluisDi Mario, CarloVeugeois, AurelieMaly, JiriSchober, AndreasNombela-Franco, LuisWerner, NikosGómez-Hospital, Joan AntoniMascherbauer, JuliaMusumeci, GiuseppeMeneveau, NicolasMeurice, ThibaudMahfoud, FelixDe Marco, FedericoSeidler, TimLeuschner, FlorianJoly, PatrickCollet, Jean-PhilippeVogt, FerdinandDi Lorenzo, EmilioKuhn, ElmarMcCalmont, GemmaRakova, RadkaWesselink, WilbertKurucova, JanaHachaturyan, ViolettaLüske, Claudia MBramlage, PeterFrank, DerkAortic Valve StenosisQuality of Health CareTranscatheter Aortic Valve ReplacementEstenosis de la Válvula AórticaCalidad de la Atención de SaludReemplazo de la Válvula Aórtica TranscatéterAortic stenosisClinical careProspective registryQuality of careTAVITranscatheter aortic valve implantationBackground: Benchmark best practices have been shown to streamline the clinical pathway for patients undergoing transcatheter aortic valve implantation (TAVI), but the impact in diverse health systems is unknown. Aims: We evaluated the impact of Benchmark best practices implementation in Germany, Austria, France, Spain, and Italy. Methods: International, multicentre registry of severe symptomatic aortic stenosis (AS) patients undergoing TAVI with a balloon-expandable valve, before and after Benchmark best practices implementation. Objectives were to reduce overall and intensive care unit (ICU) length of stay (LoS), and to document 30-day safety. Results: A total of 890 patients were analysed in France, 454 in Spain, 362 in Germany, 300 in Italy, and 176 in Austria. Patients had the highest surgical risk in Germany (EuroSCORE II 6.8 ± 7.3%) and lowest in Spain (3.8 ± 2.6%). Austrian patients reported higher rates of prior myocardial infarction, severe pulmonary hypertension, and aortic valve-related symptoms at baseline. After the implementation of Benchmark best practices, the median hospital LoS was significantly reduced in France (5 vs. 3 days, p < 0.001), Spain (6 vs. 4, p < 0.001), Germany (9 vs. 6, p < 0.001), and Italy (7 vs. 5, p < 0.001); reductions in median ICU LoS were reported in France (1.1 vs. 0 days, p < 0.001), Spain (1.9 vs. 1, p < 0.001), and Germany (1 vs. 0.9, p = 0.004). Across all countries, 30-day safety outcomes were uncompromised and reduced rates of major vascular complications rates were observed in Germany (5.9 vs. 0.0%, p < 0.001). Conclusion: The implementation of Benchmark best practices in diverse European healthcare systems resulted in reduced hospital and ICU LoS without compromising patient safety. Trial registration: ClinicalTrials.gov NCT04579445, September 28th, 2020.SpringerNature20252025-04-2220252025-04-22research articlehttp://purl.org/coar/resource_type/c_2df8fbb1info:eu-repo/semantics/articleapplication/pdfhttps://hdl.handle.net/20.500.13003/24965reponame:Docusalutinstname:Conselleria de Salut i Consum del Govern de les Illes BalearsInglésengopen accesshttp://purl.org/coar/access_right/c_abf2info:eu-repo/semantics/openAccessoai:docusalut.com:20.500.13003/249652026-06-22T12:44:07Z |
| dc.title.none.fl_str_mv |
The implementation of a streamlined TAVI patient pathway across five European countries: BENCHMARK registry. |
| title |
The implementation of a streamlined TAVI patient pathway across five European countries: BENCHMARK registry. |
| spellingShingle |
The implementation of a streamlined TAVI patient pathway across five European countries: BENCHMARK registry. Saia, Francesco. Aortic Valve Stenosis Quality of Health Care Transcatheter Aortic Valve Replacement Estenosis de la Válvula Aórtica Calidad de la Atención de Salud Reemplazo de la Válvula Aórtica Transcatéter Aortic stenosis Clinical care Prospective registry Quality of care TAVI Transcatheter aortic valve implantation |
| title_short |
The implementation of a streamlined TAVI patient pathway across five European countries: BENCHMARK registry. |
| title_full |
The implementation of a streamlined TAVI patient pathway across five European countries: BENCHMARK registry. |
| title_fullStr |
The implementation of a streamlined TAVI patient pathway across five European countries: BENCHMARK registry. |
| title_full_unstemmed |
The implementation of a streamlined TAVI patient pathway across five European countries: BENCHMARK registry. |
| title_sort |
The implementation of a streamlined TAVI patient pathway across five European countries: BENCHMARK registry. |
| dc.creator.none.fl_str_mv |
Saia, Francesco. Lauck, Sandra Durand, Eric Muir, Douglas F Spence, Mark Vasa-Nicotera, Mariuca Wood, David Urbano-Carrillo, Cristóbal A Bouchayer, Damien Iliescu, Vlad Anton Etienne, Christophe Saint Leclercq, Florence Auffret, Vincent Asmarats, Lluis Di Mario, Carlo Veugeois, Aurelie Maly, Jiri Schober, Andreas Nombela-Franco, Luis Werner, Nikos Gómez-Hospital, Joan Antoni Mascherbauer, Julia Musumeci, Giuseppe Meneveau, Nicolas Meurice, Thibaud Mahfoud, Felix De Marco, Federico Seidler, Tim Leuschner, Florian Joly, Patrick Collet, Jean-Philippe Vogt, Ferdinand Di Lorenzo, Emilio Kuhn, Elmar McCalmont, Gemma Rakova, Radka Wesselink, Wilbert Kurucova, Jana Hachaturyan, Violetta Lüske, Claudia M Bramlage, Peter Frank, Derk |
| author |
Saia, Francesco. |
| author_facet |
Saia, Francesco. Lauck, Sandra Durand, Eric Muir, Douglas F Spence, Mark Vasa-Nicotera, Mariuca Wood, David Urbano-Carrillo, Cristóbal A Bouchayer, Damien Iliescu, Vlad Anton Etienne, Christophe Saint Leclercq, Florence Auffret, Vincent Asmarats, Lluis Di Mario, Carlo Veugeois, Aurelie Maly, Jiri Schober, Andreas Nombela-Franco, Luis Werner, Nikos Gómez-Hospital, Joan Antoni Mascherbauer, Julia Musumeci, Giuseppe Meneveau, Nicolas Meurice, Thibaud Mahfoud, Felix De Marco, Federico Seidler, Tim Leuschner, Florian Joly, Patrick Collet, Jean-Philippe Vogt, Ferdinand Di Lorenzo, Emilio Kuhn, Elmar McCalmont, Gemma Rakova, Radka Wesselink, Wilbert Kurucova, Jana Hachaturyan, Violetta Lüske, Claudia M Bramlage, Peter Frank, Derk |
| author_role |
author |
| author2 |
Lauck, Sandra Durand, Eric Muir, Douglas F Spence, Mark Vasa-Nicotera, Mariuca Wood, David Urbano-Carrillo, Cristóbal A Bouchayer, Damien Iliescu, Vlad Anton Etienne, Christophe Saint Leclercq, Florence Auffret, Vincent Asmarats, Lluis Di Mario, Carlo Veugeois, Aurelie Maly, Jiri Schober, Andreas Nombela-Franco, Luis Werner, Nikos Gómez-Hospital, Joan Antoni Mascherbauer, Julia Musumeci, Giuseppe Meneveau, Nicolas Meurice, Thibaud Mahfoud, Felix De Marco, Federico Seidler, Tim Leuschner, Florian Joly, Patrick Collet, Jean-Philippe Vogt, Ferdinand Di Lorenzo, Emilio Kuhn, Elmar McCalmont, Gemma Rakova, Radka Wesselink, Wilbert Kurucova, Jana Hachaturyan, Violetta Lüske, Claudia M Bramlage, Peter Frank, Derk |
| author2_role |
author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author |
| dc.contributor.none.fl_str_mv |
|
| dc.subject.none.fl_str_mv |
Aortic Valve Stenosis Quality of Health Care Transcatheter Aortic Valve Replacement Estenosis de la Válvula Aórtica Calidad de la Atención de Salud Reemplazo de la Válvula Aórtica Transcatéter Aortic stenosis Clinical care Prospective registry Quality of care TAVI Transcatheter aortic valve implantation |
| topic |
Aortic Valve Stenosis Quality of Health Care Transcatheter Aortic Valve Replacement Estenosis de la Válvula Aórtica Calidad de la Atención de Salud Reemplazo de la Válvula Aórtica Transcatéter Aortic stenosis Clinical care Prospective registry Quality of care TAVI Transcatheter aortic valve implantation |
| description |
Background: Benchmark best practices have been shown to streamline the clinical pathway for patients undergoing transcatheter aortic valve implantation (TAVI), but the impact in diverse health systems is unknown. Aims: We evaluated the impact of Benchmark best practices implementation in Germany, Austria, France, Spain, and Italy. Methods: International, multicentre registry of severe symptomatic aortic stenosis (AS) patients undergoing TAVI with a balloon-expandable valve, before and after Benchmark best practices implementation. Objectives were to reduce overall and intensive care unit (ICU) length of stay (LoS), and to document 30-day safety. Results: A total of 890 patients were analysed in France, 454 in Spain, 362 in Germany, 300 in Italy, and 176 in Austria. Patients had the highest surgical risk in Germany (EuroSCORE II 6.8 ± 7.3%) and lowest in Spain (3.8 ± 2.6%). Austrian patients reported higher rates of prior myocardial infarction, severe pulmonary hypertension, and aortic valve-related symptoms at baseline. After the implementation of Benchmark best practices, the median hospital LoS was significantly reduced in France (5 vs. 3 days, p < 0.001), Spain (6 vs. 4, p < 0.001), Germany (9 vs. 6, p < 0.001), and Italy (7 vs. 5, p < 0.001); reductions in median ICU LoS were reported in France (1.1 vs. 0 days, p < 0.001), Spain (1.9 vs. 1, p < 0.001), and Germany (1 vs. 0.9, p = 0.004). Across all countries, 30-day safety outcomes were uncompromised and reduced rates of major vascular complications rates were observed in Germany (5.9 vs. 0.0%, p < 0.001). Conclusion: The implementation of Benchmark best practices in diverse European healthcare systems resulted in reduced hospital and ICU LoS without compromising patient safety. Trial registration: ClinicalTrials.gov NCT04579445, September 28th, 2020. |
| publishDate |
2025 |
| dc.date.none.fl_str_mv |
2025 2025-04-22 2025 2025-04-22 |
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research article http://purl.org/coar/resource_type/c_2df8fbb1 |
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info:eu-repo/semantics/article |
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article |
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https://hdl.handle.net/20.500.13003/24965 |
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https://hdl.handle.net/20.500.13003/24965 |
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Inglés eng |
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Inglés |
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eng |
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open access http://purl.org/coar/access_right/c_abf2 |
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info:eu-repo/semantics/openAccess |
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open access http://purl.org/coar/access_right/c_abf2 |
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openAccess |
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application/pdf |
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SpringerNature |
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SpringerNature |
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reponame:Docusalut instname:Conselleria de Salut i Consum del Govern de les Illes Balears |
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