Implementation of the agmatine-controlled expression system for inducible gene expression in Lactococcus lactis

[Background] Lactococcus lactis has been safely consumed in fermented foods for millennia. This Gram-positive bacterium has now become of industrial importance as an expression host for the overproduction of lipopolysaccharide-free recombinant proteins used as food ingredients, therapeutic proteins...

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Detalhes bibliográficos
Autores: Linares, Daniel M., Álvarez Sieiro, Patricia, Río Lagar, Beatriz del, Ladero Losada, Víctor Manuel, Redruello, Begoña, Martín, M. Cruz, Fernández García, María, Álvarez González, Miguel Ángel
Tipo de documento: artigo
Estado:Versão publicada
Data de publicação:2015
País:España
Recursos:Consejo Superior de Investigaciones Científicas (CSIC)
Repositório:DIGITAL.CSIC. Repositorio Institucional del CSIC
OAI Identifier:oai:digital.csic.es:10261/143003
Acesso em linha:http://hdl.handle.net/10261/143003
Access Level:Acceso aberto
Palavra-chave:Lactococcus lactis
Myxococcus xanthus
Agmatine induction
Expression vector
Prolyl-endopeptidase
Descrição
Resumo:[Background] Lactococcus lactis has been safely consumed in fermented foods for millennia. This Gram-positive bacterium has now become of industrial importance as an expression host for the overproduction of lipopolysaccharide-free recombinant proteins used as food ingredients, therapeutic proteins and biotechnological enzymes.