Pharmacological Synergism: A Multimodal Analgesia Approach to Treat Dental Pain

Dental pain is usually managed by clinical interventions and pharmacological coadjuvants such as NSAIDs. However, its perception and modulation is mediated by different nociceptive mechanisms and these strategies can be insufficient. The multimodal analgesia refers to the use of 2 or more analgesic...

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Detalhes bibliográficos
Autores: Chavarría-Bolaños MSc, PhD, Daniel, Esparza-Villalpando MSc, Vicente, Pozos-Guillén MSc, PhD, Amaury
Tipo de documento: artigo
Estado:Versão publicada
Data de publicação:2019
País:Costa Rica
Recursos:Universidad de Costa Rica
Repositório:Portal de Revistas UCR
Idioma:inglês
OAI Identifier:oai:portal.ucr.ac.cr:article/34926
Acesso em linha:https://revistas.ucr.ac.cr/index.php/Odontos/article/view/34926
Access Level:Acceso aberto
Palavra-chave:Multimodal analgesia
Pharmacological synergism
Dental pain
Descrição
Resumo:Dental pain is usually managed by clinical interventions and pharmacological coadjuvants such as NSAIDs. However, its perception and modulation is mediated by different nociceptive mechanisms and these strategies can be insufficient. The multimodal analgesia refers to the use of 2 or more analgesic drugs that attenuate or blockade different mechanisms of pain, obtaining a greater clinical effect. Within this concept, pharmacological synergism plays a leading role, combining different molecules in lower doses to diminish also side effects. Since there are no standard prescriptions to be use in all the patients, multimodal approaches allow the clinician to make responsible effective combinations, individualizing analgesia as the pathway to success.