Autoimmune hemolytic anemia mediated by IgG and IgA in a patient with ulcerative colitis

Chronic ulcerative indeterminate colitis (CUCI) is characterized by inflammation that primarily affects the rectum and may extend continuously to the colon. Anemia is common in patients with CUCI because of bleeding and the chronicity of the disease. However, CUCI has an immunological component. CUC...

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Detalhes bibliográficos
Autores: Rivera Barquero, Ángelo, Cano López, Francis
Formato: artículo
Estado:Versión publicada
Fecha de publicación:2015
País:Costa Rica
Recursos:Universidad de Costa Rica
Repositorio:Portal de Revistas UCR
Idioma:español
OAI Identifier:oai:portal.ucr.ac.cr:article/19622
Acesso em linha:https://revistas.ucr.ac.cr/index.php/medica/article/view/19622
Access Level:acceso abierto
Palavra-chave:colitis ulcerativa
anemia hemolítica autoinmune
enteropatía autoinmune
ulcerative colitis
autoimmune hemolytic anemia
autoinmune enteropathy
Descrição
Resumo:Chronic ulcerative indeterminate colitis (CUCI) is characterized by inflammation that primarily affects the rectum and may extend continuously to the colon. Anemia is common in patients with CUCI because of bleeding and the chronicity of the disease. However, CUCI has an immunological component. CUCI decrease the immune tolerance, which can lead in some cases to autoimmune hemolytic anemia (AIHA) usually mediated by antibodies of the IgG type. The patient in this case presents an AIHA associated with CUCI mediated both IgG and IgA antibodies, so it is an extremely rare situation.