Reducing the impact of snakebite envenoming in Latin America and the Caribbean: achievements and challenges ahead

Snakebite envenoming constitutes an important public health problem in Latin America and some countries of the Caribbean. The advances and pending tasks in the study and control of this neglected tropical disease in this region are reviewed in the light of a roadmap proposed in 2006. Significant pro...

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Detalhes bibliográficos
Autor: Gutiérrez, José María
Tipo de documento: artigo
Data de publicação:2014
País:Costa Rica
Recursos:Universidad de Costa Rica
Repositório:Kérwá
OAI Identifier:oai:kerwa.ucr.ac.cr:10669/30125
Acesso em linha:https://academic.oup.com/trstmh/article-lookup/doi/10.1093/trstmh/tru102
https://hdl.handle.net/10669/30125
Access Level:Acesso embargado
Palavra-chave:Antivenoms
Caribbean
Envenoming
Latin America
Snakebite
Venoms
Snake venom
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dc.title.es_ES.fl_str_mv Reducing the impact of snakebite envenoming in Latin America and the Caribbean: achievements and challenges ahead
title Reducing the impact of snakebite envenoming in Latin America and the Caribbean: achievements and challenges ahead
spellingShingle Reducing the impact of snakebite envenoming in Latin America and the Caribbean: achievements and challenges ahead
Gutiérrez, José María
Antivenoms
Caribbean
Envenoming
Latin America
Snakebite
Venoms
Snake venom
title_short Reducing the impact of snakebite envenoming in Latin America and the Caribbean: achievements and challenges ahead
title_full Reducing the impact of snakebite envenoming in Latin America and the Caribbean: achievements and challenges ahead
title_fullStr Reducing the impact of snakebite envenoming in Latin America and the Caribbean: achievements and challenges ahead
title_full_unstemmed Reducing the impact of snakebite envenoming in Latin America and the Caribbean: achievements and challenges ahead
title_sort Reducing the impact of snakebite envenoming in Latin America and the Caribbean: achievements and challenges ahead
dc.creator.none.fl_str_mv Gutiérrez, José María
author Gutiérrez, José María
author_facet Gutiérrez, José María
author_role author
dc.subject.es_ES.fl_str_mv Antivenoms
Caribbean
Envenoming
Latin America
Snakebite
Venoms
Snake venom
topic Antivenoms
Caribbean
Envenoming
Latin America
Snakebite
Venoms
Snake venom
description Snakebite envenoming constitutes an important public health problem in Latin America and some countries of the Caribbean. The advances and pending tasks in the study and control of this neglected tropical disease in this region are reviewed in the light of a roadmap proposed in 2006. Significant progress has been achieved in the study of snake venoms, particularly regarding venom proteomics, i.e.‘venomics’, and the analysis of the mechanism of action of toxins. Likewise, a deeper understanding has been gained in the preclinical efficacy of antivenoms produced in the region. In contrast, despite advances made in the study of clinical manifestations of envenomings and safety and efficacy of antivenoms at the clinical level, much remains to be done in this subject. Improvements have occurred in antivenom manufacturing technologies and availability, although there are still countries where there is insufficient supply of antivenoms, or where manufacture has to be improved. In spite of considerable efforts in some countries in prevention, accessibility to treatment, and training of health staff in the management of envenomings, important challenges remain for the region as a whole, with the long term goal of reducing the impact of this disease in terms of personal and social suffering.
publishDate 2014
dc.date.issued.none.fl_str_mv 2014-09-01
dc.date.accessioned.none.fl_str_mv 2017-06-16T20:15:50Z
dc.date.available.none.fl_str_mv 2017-06-16T20:15:50Z
dc.type.none.fl_str_mv artículo original
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dc.identifier.issn.none.fl_str_mv 1878-3503
dc.identifier.uri.none.fl_str_mv https://hdl.handle.net/10669/30125
dc.identifier.doi.none.fl_str_mv 10.1093/trstmh/tru102
dc.identifier.pmid.none.fl_str_mv 25096295
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dc.source.es_ES.fl_str_mv Transactions of The Royal Society of Tropical Medicine and Hygiene; Volumen 108, Número 9. 2014
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spelling Gutiérrez, José María6a9bac5f-130f-4977-8ddf-ab97fcafacc46002017-06-16T20:15:50Z2017-06-16T20:15:50Z2014-09-01https://academic.oup.com/trstmh/article-lookup/doi/10.1093/trstmh/tru1021878-3503https://hdl.handle.net/10669/3012510.1093/trstmh/tru10225096295Snakebite envenoming constitutes an important public health problem in Latin America and some countries of the Caribbean. The advances and pending tasks in the study and control of this neglected tropical disease in this region are reviewed in the light of a roadmap proposed in 2006. Significant progress has been achieved in the study of snake venoms, particularly regarding venom proteomics, i.e.‘venomics’, and the analysis of the mechanism of action of toxins. Likewise, a deeper understanding has been gained in the preclinical efficacy of antivenoms produced in the region. In contrast, despite advances made in the study of clinical manifestations of envenomings and safety and efficacy of antivenoms at the clinical level, much remains to be done in this subject. Improvements have occurred in antivenom manufacturing technologies and availability, although there are still countries where there is insufficient supply of antivenoms, or where manufacture has to be improved. In spite of considerable efforts in some countries in prevention, accessibility to treatment, and training of health staff in the management of envenomings, important challenges remain for the region as a whole, with the long term goal of reducing the impact of this disease in terms of personal and social suffering.Universidad de Costa Rica//UCR/Costa RicaUCR::Vicerrectoría de Investigación::Unidades de Investigación::Ciencias de la Salud::Instituto Clodomiro Picado (ICP)en_USacceso embargadohttp://purl.org/coar/access_right/c_f1cfinfo:eu-repo/semantics/embargoedAccessTransactions of The Royal Society of Tropical Medicine and Hygiene; Volumen 108, Número 9. 2014reponame:Kérwáinstname:Universidad de Costa Ricainstacron:UCRAntivenomsCaribbeanEnvenomingLatin AmericaSnakebiteVenomsSnake venomReducing the impact of snakebite envenoming in Latin America and the Caribbean: achievements and challenges aheadartículo originalhttp://purl.org/coar/resource_type/c_2df8fbb1info:eu-repo/semantics/articleTHUMBNAIL382_2014_TRSTMH_Gutiérrez_snakebite_Latin_America_Caribbean.pdf.jpg382_2014_TRSTMH_Gutiérrez_snakebite_Latin_America_Caribbean.pdf.jpgGenerated Thumbnailimage/jpeg5103https://www.kerwa.ucr.ac.cr/bitstreams/083e7d9b-9888-4b9a-ba3a-f5af61f45f00/download98c162734b433d4373b7b575d895338cMD54ORIGINAL382_2014_TRSTMH_Gutiérrez_snakebite_Latin_America_Caribbean.pdf382_2014_TRSTMH_Gutiérrez_snakebite_Latin_America_Caribbean.pdfapplication/pdf444850https://www.kerwa.ucr.ac.cr/bitstreams/9173c1af-c3a3-4984-9965-488fdca8612e/download1dd1c7c7ebe08703a0d5ef4b21a25887MD51LICENSElicense.txtlicense.txttext/plain; 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