Active metabolites of the genus Piper against Aedes aegypti: natural alternative sources for dengue vector control

The mosquito, Aedes aegypti, is the principal vector of the viruses responsible for dengue and dengue hemorrhagic fevers. The mosquito is widespread throughout tropical and sub-tropical regions; its prevalence makes dengue one of the most important mosquito-borne viral diseases in the world occurrin...

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Detalhes bibliográficos
Autores: Marques, Andre, C. Kaplan, Maria Auxiliadora
Formato: artículo
Estado:Versión publicada
Fecha de publicación:2014
País:Colombia
Recursos:Pontificia Universidad Javeriana
Repositorio:Repositorio Universidad Javeriana
Idioma:inglés
OAI Identifier:oai:repository.javeriana.edu.co:10554/31334
Acesso em linha:http://revistas.javeriana.edu.co/index.php/scientarium/article/view/7203
http://hdl.handle.net/10554/31334
Access Level:acceso abierto
Palavra-chave:null
dengue; Aedes aegypti; Piper; Piperaceae; larvicidal metabolites; tropical diseases
Descrição
Resumo:The mosquito, Aedes aegypti, is the principal vector of the viruses responsible for dengue and dengue hemorrhagic fevers. The mosquito is widespread throughout tropical and sub-tropical regions; its prevalence makes dengue one of the most important mosquito-borne viral diseases in the world occurring annually in more than 100 endemic countries. Because blood is essential to their development cycle, the Aedes species maintains a close association with humans and their dwellings. Fittingly, the most widely adopted strategy to decrease the incidence of these diseases is the control of the mosquito larvae population. The emergence of insecticide-resistant mosquitoes has amplified the interest in finding natural products effective against Aedes aegypti adults, as well as larvae. Plant-derived compounds have played an important role in the discovery of new active entities for vector management as they are safer and have lower toxicity to humans in comparison to conventional insecticides. This review assesses a naturally occurring plant matrix and pure compounds of the Piper species, which have been shown to be active against Aedes aegypti.