Characterization of the enterobacteriaceae-associated rod21-like family of excisable genomic islands and study of excision inn the pathogenicity island rod21

Genomic islands (GI) are horizontally acquired elements that play a major role in genome evolution and bacterial adaptation to different environments. The results of this thesis expand the repertory of identified excisable genomic islands, presenting insights about their evolution, and provide a fir...

ver descrição completa

Detalhes bibliográficos
Autor: Piña-Iturbe, Luis Alejandro
Formato: tesis doctoral
Estado:Versión publicada
Fecha de publicación:2021
País:Chile
OAI Identifier:oai:repositorio.anid.cl:10533/253223
Acesso em linha:https://hdl.handle.net/10533/253223
Access Level:acceso abierto
Palavra-chave:Ciencias Naturales
Ciencias de la Tierra y del Medio Ambiente
Microbiología
Descrição
Resumo:Genomic islands (GI) are horizontally acquired elements that play a major role in genome evolution and bacterial adaptation to different environments. The results of this thesis expand the repertory of identified excisable genomic islands, presenting insights about their evolution, and provide a first approach to the understanding of the regulation of excision in the pathogenicity island ROD21. These findings may contribute to the better understanding of current and emerging pathogens such as Salmonella serovars, pathogenic E. coli and carbapenem-resistant K. pneumoniae ST258, among others.