Produção de ciclodextrinas na presença de etanol e formação de complexos de inclusão ciclodextrina/enrofloxacina

In Brazil, although there is a great incentive for the production of cliclodextrinas (CDs) due to their high added value and the raw material (starch) is available at low cost, there are no industrial processes for their production. Therefore, the proposal of this work had as objective the developme...

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Detalhes bibliográficos
Autor: Calsavara, Luiza Pedrina Vilxenski
Formato: tesis doctoral
Estado:Versión publicada
Fecha de publicación:2010
País:Brasil
Recursos:Universidade Estadual de Maringá (UEM)
Repositorio:Repositório Institucional da Universidade Estadual de Maringá (RI-UEM)
Idioma:portugués
OAI Identifier:oai:localhost:1/3668
Acesso em linha:http://repositorio.uem.br:8080/jspui/handle/1/3668
Access Level:acceso abierto
Palavra-chave:Ciclodextrina
Etanol
Toruzyme
Milho
Mandioca
Brasil
Cyclodextrin
Ethanol
Corn
Cassava
Brazil
Engenharias
Engenharia Química
Descrição
Resumo:In Brazil, although there is a great incentive for the production of cliclodextrinas (CDs) due to their high added value and the raw material (starch) is available at low cost, there are no industrial processes for their production. Therefore, the proposal of this work had as objective the development of technology for production and separation of CDs from single batch and sequential batch processes, using commercial cornstarch andcassava starch, with or without pretreatment of starch granules, and commercial cyclomaltodextringlucantransferase enzyme(CGTase), in the presence andabsence of ethanol. It was also studied the pharmacological application of CDs through the formation of inclusion complex with enrofloxacin (FLOX), to remove the bitter taste and increase the solubility of this antibiotic.