Bone changes in infants with congenital syphilis

Introduction: syphilis morbidity in intra-uterine life, produces negative outcomes in more than 50% of cases and complications in live births. Bone injuries are frequent in congenital syphilis (CS), occurring in 70 to 100% of the cases. Objective: to report cases of ten infants diagnosed with early...

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Autores: Silva, Sandra F Moreira, Prebianchi, Patricia A., Dias, Carolina F., Akel Júnior, Akel N., Dalvi, Ludmila G., Frauches, Diana O.
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2009
País:Brasil
Institución:Sociedade Brasileira de Doenças Sexualmente Transmissíveis
Repositorio:DST (Niterói. Online)
Idioma:portugués
OAI Identifier:oai:ojs.bjstd.org:article/1004
Acceso en línea:https://www.bjstd.org/revista/article/view/1004
Access Level:acceso abierto
Palabra clave:sífilis congênita
periostite
alterações radiológicas
DST
congenital syphilis
periostitis
radiological changes
STD
id BR_f7a8b79df09f6aba80fd8d4ba3459dd2
oai_identifier_str oai:ojs.bjstd.org:article/1004
network_acronym_str BR
network_name_str Brasil
repository_id_str
dc.title.none.fl_str_mv Bone changes in infants with congenital syphilis
Alterações ósseas em lactentes com sífilis congênita
title Bone changes in infants with congenital syphilis
spellingShingle Bone changes in infants with congenital syphilis
Silva, Sandra F Moreira
sífilis congênita
periostite
alterações radiológicas
DST
congenital syphilis
periostitis
radiological changes
STD
title_short Bone changes in infants with congenital syphilis
title_full Bone changes in infants with congenital syphilis
title_fullStr Bone changes in infants with congenital syphilis
title_full_unstemmed Bone changes in infants with congenital syphilis
title_sort Bone changes in infants with congenital syphilis
dc.creator.none.fl_str_mv Silva, Sandra F Moreira
Prebianchi, Patricia A.
Dias, Carolina F.
Akel Júnior, Akel N.
Dalvi, Ludmila G.
Frauches, Diana O.
author Silva, Sandra F Moreira
author_facet Silva, Sandra F Moreira
Prebianchi, Patricia A.
Dias, Carolina F.
Akel Júnior, Akel N.
Dalvi, Ludmila G.
Frauches, Diana O.
author_role author
author2 Prebianchi, Patricia A.
Dias, Carolina F.
Akel Júnior, Akel N.
Dalvi, Ludmila G.
Frauches, Diana O.
author2_role author
author
author
author
author
dc.subject.por.fl_str_mv sífilis congênita
periostite
alterações radiológicas
DST
congenital syphilis
periostitis
radiological changes
STD
topic sífilis congênita
periostite
alterações radiológicas
DST
congenital syphilis
periostitis
radiological changes
STD
description Introduction: syphilis morbidity in intra-uterine life, produces negative outcomes in more than 50% of cases and complications in live births. Bone injuries are frequent in congenital syphilis (CS), occurring in 70 to 100% of the cases. Objective: to report cases of ten infants diagnosed with early SC and bone changes to the radiological examination of long bones, accompanied in the infectology service of HINSG. Case report: ten infants had bone injuries among children hospitalized with CS in HINSG, six female and four male. Half of the metropolitan region of Vitória, two from the interior and three from state of Bahia. Two were less than a month old. Six of the mothers had prenatal care, three were diagnosed with syphilis during pregnancy and only one was properly treated. Two children had osteomyelitis, and with a lytic lesion in the tibia and the other had periostitis. More than one bone was affected in six infants. Bones most affected: tibia (7/10), femur (6/10), humerus (5/10), radio (2/10) and ulna (2/10). Common symptom among all were frequent crying with movement of members. Reason why mothers have sought medical service. Discussion: changes are important in radiological diagnosis of CS. In this study 60% of mothers have prenatal care, one was treated correctly and none of the children were diagnosed and treated soon after birth, only receiving proper medication after diagnosis in our service. Radiological changes of CS may happen after installation according to time of infection. Various injuries may occur, including injuries of CS early: osteomyelitis diaphyseal, osteítes and periostitis. Osteochondritis affects cartilage in areas of growth. Injury of late CS are severe, can cause physical deformities and pathological fracture in children, necrosis of bone and osteolysis in adults and sometimes linking up with pyogenic infection or spread to adjacent tissues, with formation of fistulas skin painless.
publishDate 2009
dc.date.none.fl_str_mv 2009-12-06
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://www.bjstd.org/revista/article/view/1004
url https://www.bjstd.org/revista/article/view/1004
dc.language.iso.fl_str_mv por
language por
dc.relation.none.fl_str_mv https://www.bjstd.org/revista/article/view/1004/898
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Sociedade Brasileira de Doenças Sexualmente Transmissíveis
publisher.none.fl_str_mv Sociedade Brasileira de Doenças Sexualmente Transmissíveis
dc.source.none.fl_str_mv Brazilian Journal of Sexually Transmitted Diseases; Vol. 21 No. 4 (2009); 175-178
Brazilian Journal of Sexually Transmitted Diseases; v. 21 n. 4 (2009); 175-178
2177-8264
reponame:DST (Niterói. Online)
instname:Sociedade Brasileira de Doenças Sexualmente Transmissíveis
instacron:SBDST
instname_str Sociedade Brasileira de Doenças Sexualmente Transmissíveis
instacron_str SBDST
institution SBDST
reponame_str DST (Niterói. Online)
collection DST (Niterói. Online)
repository.name.fl_str_mv DST (Niterói. Online) - Sociedade Brasileira de Doenças Sexualmente Transmissíveis
repository.mail.fl_str_mv maurodst@gmail.com | producao@zeppelini.com.br | secretaria@zeppelini.com.br
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spelling Bone changes in infants with congenital syphilisAlterações ósseas em lactentes com sífilis congênitasífilis congênitaperiostitealterações radiológicasDSTcongenital syphilisperiostitisradiological changesSTDIntroduction: syphilis morbidity in intra-uterine life, produces negative outcomes in more than 50% of cases and complications in live births. Bone injuries are frequent in congenital syphilis (CS), occurring in 70 to 100% of the cases. Objective: to report cases of ten infants diagnosed with early SC and bone changes to the radiological examination of long bones, accompanied in the infectology service of HINSG. Case report: ten infants had bone injuries among children hospitalized with CS in HINSG, six female and four male. Half of the metropolitan region of Vitória, two from the interior and three from state of Bahia. Two were less than a month old. Six of the mothers had prenatal care, three were diagnosed with syphilis during pregnancy and only one was properly treated. Two children had osteomyelitis, and with a lytic lesion in the tibia and the other had periostitis. More than one bone was affected in six infants. Bones most affected: tibia (7/10), femur (6/10), humerus (5/10), radio (2/10) and ulna (2/10). Common symptom among all were frequent crying with movement of members. Reason why mothers have sought medical service. Discussion: changes are important in radiological diagnosis of CS. In this study 60% of mothers have prenatal care, one was treated correctly and none of the children were diagnosed and treated soon after birth, only receiving proper medication after diagnosis in our service. Radiological changes of CS may happen after installation according to time of infection. Various injuries may occur, including injuries of CS early: osteomyelitis diaphyseal, osteítes and periostitis. Osteochondritis affects cartilage in areas of growth. Injury of late CS are severe, can cause physical deformities and pathological fracture in children, necrosis of bone and osteolysis in adults and sometimes linking up with pyogenic infection or spread to adjacent tissues, with formation of fistulas skin painless.Introdução: a sífilis causa morbidade na vida intrauterina, desfechos negativos em mais de 50% dos casos e complicações nos nascidos vivos. Lesões ósseas são frequentes na sífilis congênita (SC), ocorrendo em 70 a 100% dos casos. Objetivo: relatar casos de dez lactentes com diagnóstico de SC precoce e alterações ósseas ao exame radiológico de ossos longos, acompanhados no Serviço de Infectologia do HINSG. Relato dos casos: dez lactentes apresentaram lesões ósseas, entre crianças internadas com SC no HINSG, seis do sexo feminino e quatro do masculino. Metade era proveniente da Grande Vitória, três do interior e dois da Bahia. Dois tinham menos de 1 mês de vida. Seis das mães fizeram pré-natal, três tiveram o diagnóstico de sífilis na gestação e apenas uma foi adequadamente tratada. Duas crianças apresentaram osteomielite, sendo uma com lesão lítica na tíbia e as demais tiveram periostite. Mais de um osso foi afetado em seis lactentes. Os ossos mais afetados foram: tíbia (7/10), fêmur (6/10), úmero (5/10), rádio (2/10) e ulna (2/10). Sintoma comum entre todos foi choro frequente ao movimento de membros superiores ou inferiores, motivo de as mães terem procurado o serviço médico. Discussão: alterações radiológicas são importantes no diagnóstico de SC. Neste estudo, 60% das mães fizeram pré-natal, uma foi tratada corretamente e nenhuma das crianças foi diagnosticada e tratada logo após o nascimento, somente recebendo medicação adequada após o diagnóstico no nosso serviço. Alterações radiológicas da SC podem acontecer em tempo variado após a instalação da infecção. Podem ocorrer diferentes lesões, que incluem lesões da SC precoce: osteomielite diaíisária, osteítes e periostite. Osteocondrite afeta áreas da cartilagem em crescimento. Lesões da SC tardia são severas, podem causar deformidades físicas e fratura patológica na criança, necrose de osso e osteólise no adulto e, às vezes associam-se a infecção piogênica ou difusão para tecidos adjacentes, com formações de fístulas cutâneas indolores.Sociedade Brasileira de Doenças Sexualmente Transmissíveis2009-12-06info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://www.bjstd.org/revista/article/view/1004Brazilian Journal of Sexually Transmitted Diseases; Vol. 21 No. 4 (2009); 175-178Brazilian Journal of Sexually Transmitted Diseases; v. 21 n. 4 (2009); 175-1782177-8264reponame:DST (Niterói. Online)instname:Sociedade Brasileira de Doenças Sexualmente Transmissíveisinstacron:SBDSTporhttps://www.bjstd.org/revista/article/view/1004/898info:eu-repo/semantics/openAccessSilva, Sandra F MoreiraPrebianchi, Patricia A.Dias, Carolina F.Akel Júnior, Akel N.Dalvi, Ludmila G.Frauches, Diana O.2022-02-01T16:09:33Zoai:ojs.bjstd.org:article/1004Revistahttps://www.bjstd.org/revistaONGhttps://www.bjstd.org/revista/oaimaurodst@gmail.com | producao@zeppelini.com.br | secretaria@zeppelini.com.br2177-82640103-4065opendoar:2022-02-01T16:09:33DST (Niterói. Online) - Sociedade Brasileira de Doenças Sexualmente Transmissíveisfalse
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