Osteointegração de osso bovino desvitalizado, hidroxiapatita de coral, poliuretana de mamona e enxerto autógeno em coelhos

PURPOSE: To study comparatively devitalized bovine bone, porous coralline hydroxyapatite, castor beans polyurethane implants and autograft in the repair of 6x10mm bony defect in femur of rabbits. METHODS: Ninety six New Zealand rabbits were distributed in 4 groups conforms the material of replacemen...

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Bibliographic Details
Authors: Figueiredo, Arthur Silveira de [UNIFESP], Fagundes, Djalma José [UNIFESP], Novo, Neil Ferreira [UNIFESP], Inouye, Celso Massaschi [UNIFESP], Takita, Luiz Carlos [UNIFESP], Sassioto, Maria Cristina Pita [UNIFESP]
Format: article
Status:Published version
Publication Date:2004
Country:Brasil
Institution:Universidade Federal de São Paulo (UNIFESP)
Repository:Repositório Institucional da UNIFESP
Language:Portuguese
OAI Identifier:oai:repositorio.unifesp.br:11600/2167
Online Access:http://dx.doi.org/10.1590/S0102-86502004000400008
http://repositorio.unifesp.br/handle/11600/2167
Access Level:Open access
Keyword:Bovine bone
Hydroxyapatite
Polimer
Autograft
Rabbit
Osso bovino
Hidroxiapatita
Polímero
Transplante autógeno
Coelhos
Description
Summary:PURPOSE: To study comparatively devitalized bovine bone, porous coralline hydroxyapatite, castor beans polyurethane implants and autograft in the repair of 6x10mm bony defect in femur of rabbits. METHODS: Ninety six New Zealand rabbits were distributed in 4 groups conforms the material of replacement of the bony defect. After following of 4 and 12 weeks, the pieces were submitted the macroscopic, microscopic, radiographic, tomographic and histometric analysis. To data was applied Kruskal-Wallis, Mann-Whitney, Fisher, t-Student and qui-square statistical tests. RESULTS: The autograft showed greatest osteogenic potential; the devitalized bovine bone produces larger inflammatory reaction, larger number of cystic cavities and slowness integration; the porous coralline hydroxyapatite maintains the initial radiodensity; devitalized bovine bone and castor beans polyurethane implants showed increased radiodensities as they were invaded by the bony formation. CONCLUSION: Devitalized bovine bone implants induces slower bony formation, when compared to the autograft, porous coralline hydroxyapatite and castor beans polyurethane implants.

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