Perfusão por tomografia computadorizada do abdome: aplicações clínicas, princípios e técnica do exame

New imaging techniques have been developed with the objective of obtaining not only a structural assessment, but also a metabolic and functional analysis of different organs and types of lesions. Among such tools perfusion computed tomography (PCT) has recently aroused the interest of many researche...

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Detalles Bibliográficos
Autores: Sousa, João Paulo Lira Barros Almeida de [UNIFESP], Bekhor, Daniel [UNIFESP], Saito Filho, Celso Fernando [UNIFESP], Bretas, Elisa Almeida Sathler [UNIFESP], D'Ippolito, Giuseppe [UNIFESP]
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2012
País:Brasil
Institución:Universidade Federal de São Paulo (UNIFESP)
Repositorio:Repositório Institucional da UNIFESP
Idioma:portugués
OAI Identifier:oai:repositorio.unifesp.br:11600/6968
Acceso en línea:http://dx.doi.org/10.1590/S0100-39842012000100010
http://repositorio.unifesp.br/handle/11600/6968
Access Level:acceso abierto
Palabra clave:Perfusion
Computed tomography
Biomarkers
Angiogenesis
Neoplasm
Contrast media
Perfusão
Tomografia computadorizada
Biomarcadores
Angiogênese
Neoplasia
Meios de contraste
Descripción
Sumario:New imaging techniques have been developed with the objective of obtaining not only a structural assessment, but also a metabolic and functional analysis of different organs and types of lesions. Among such tools perfusion computed tomography (PCT) has recently aroused the interest of many researchers in studying the applicability of such imaging modality in the evaluation of abdominal organs and diseases. Analysis of the biological behavior of healthy and diseased tissues, differentiation of inflammatory processes from tumors, and diagnosis of tumor recurrence after minimally invasive therapies can be mentioned as applications of such an imaging modality. The main features of PCT are related to its ability to characterize different perfusional behaviors reflecting biological changes of certain lesions and diseased tissues. Thus, the present study was aimed at carrying out a comprehensive literature review, describing the key techniques and protocols utilized in PCT imaging, main clinical applications, advantages and disadvantages of the method, besides proposing an imaging protocol that can be adopted by both private and public health services, with good reproducibility and easy implementation.