Aqueous extract of Psidium guajava leaves: phenolic compounds and inhibitory potential on digestive enzymes

Leaves of Psidium guajava L. (guava) have been widely used in the popular way for prevention and treatment of various diseases. Thus, the objective of this study was to evaluate the inhibitory potential of leaves aqueous extract from three cultivars of P. guajava (Pedro Sato, Paluma and Século XXI)...

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Detalles Bibliográficos
Autores: Simão, Anderson Assaid, Marques, Tamara R., Marcussi, Silvana, Correa, Angelita Duarte
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2017
País:Brasil
Institución:Universidade Federal de Lavras (UFLA)
Repositorio:Repositório Institucional da UFLA
Idioma:inglés
OAI Identifier:oai:repositorio.ufla.br:1/29864
Acceso en línea:https://repositorio.ufla.br/handle/1/29864
Access Level:acceso abierto
Palabra clave:Medicinal plants
Obesity
α-amylase
α-glycosidase
Lipase
Trypsin
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dc.title.pt_BR.fl_str_mv Aqueous extract of Psidium guajava leaves: phenolic compounds and inhibitory potential on digestive enzymes
title Aqueous extract of Psidium guajava leaves: phenolic compounds and inhibitory potential on digestive enzymes
spellingShingle Aqueous extract of Psidium guajava leaves: phenolic compounds and inhibitory potential on digestive enzymes
Simão, Anderson Assaid
Medicinal plants
Obesity
α-amylase
α-glycosidase
Lipase
Trypsin
title_short Aqueous extract of Psidium guajava leaves: phenolic compounds and inhibitory potential on digestive enzymes
title_full Aqueous extract of Psidium guajava leaves: phenolic compounds and inhibitory potential on digestive enzymes
title_fullStr Aqueous extract of Psidium guajava leaves: phenolic compounds and inhibitory potential on digestive enzymes
title_full_unstemmed Aqueous extract of Psidium guajava leaves: phenolic compounds and inhibitory potential on digestive enzymes
title_sort Aqueous extract of Psidium guajava leaves: phenolic compounds and inhibitory potential on digestive enzymes
dc.creator.none.fl_str_mv Simão, Anderson Assaid
Marques, Tamara R.
Marcussi, Silvana
Correa, Angelita Duarte
author Simão, Anderson Assaid
author_facet Simão, Anderson Assaid
Marques, Tamara R.
Marcussi, Silvana
Correa, Angelita Duarte
author_role author
author2 Marques, Tamara R.
Marcussi, Silvana
Correa, Angelita Duarte
author2_role author
author
author
dc.subject.por.fl_str_mv Medicinal plants
Obesity
α-amylase
α-glycosidase
Lipase
Trypsin
topic Medicinal plants
Obesity
α-amylase
α-glycosidase
Lipase
Trypsin
description Leaves of Psidium guajava L. (guava) have been widely used in the popular way for prevention and treatment of various diseases. Thus, the objective of this study was to evaluate the inhibitory potential of leaves aqueous extract from three cultivars of P. guajava (Pedro Sato, Paluma and Século XXI) on α-amylase, α-glycosidase, lipase, and trypsin enzymes, in the presence or not of simulated gastric fluid and to determine the content of phenolic compounds by high performance liquid chromatography. All cultivars presented the same composition in phenolic compounds, but in different proportions. The compounds identified are gallic acid, epigallocatechin gallate, syringic acid, o-coumaric acid, resveratrol, quercetin, and catechin (which was the major compound in all the cultivars evaluated). In the absence of simulated gastric fluid, it was observed different inhibitions exercised by the leaves aqueous extracts from three cultivars of P. guajava on each enzyme. In presence of simulated gastric fluid, all cultivars showed increase in the inhibition of lipase and α-glycosidase, and decrease in inhibition of α-amylase and trypsin enzymes. These results indicate that P. guajava leaves aqueous extracts from all cultivars evaluated possess potential of use as an adjuvant in the treatment of obesity and other dyslipidemias.
publishDate 2017
dc.date.issued.fl_str_mv 2017
dc.date.accessioned.fl_str_mv 2018-08-01T20:04:42Z
dc.date.available.fl_str_mv 2018-08-01T20:04:42Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
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dc.identifier.citation.fl_str_mv SIMÃO, A. A. et al. Aqueous extract of Psidium guajava leaves: phenolic compounds and inhibitory potential on digestive enzymes. Anais da Academia Brasileira de Ciências, Rio de Janeiro, v. 89, n. 3, p. 2155-2165, 2017. Suplemento 3.
dc.identifier.uri.fl_str_mv https://repositorio.ufla.br/handle/1/29864
identifier_str_mv SIMÃO, A. A. et al. Aqueous extract of Psidium guajava leaves: phenolic compounds and inhibitory potential on digestive enzymes. Anais da Academia Brasileira de Ciências, Rio de Janeiro, v. 89, n. 3, p. 2155-2165, 2017. Suplemento 3.
url https://repositorio.ufla.br/handle/1/29864
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv Attribution 4.0 International
http://creativecommons.org/licenses/by/4.0/
info:eu-repo/semantics/openAccess
rights_invalid_str_mv Attribution 4.0 International
http://creativecommons.org/licenses/by/4.0/
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv Academia Brasileira de Ciências
publisher.none.fl_str_mv Academia Brasileira de Ciências
dc.source.pt_BR.fl_str_mv Anais da Academia Brasileira de Ciências
dc.source.none.fl_str_mv reponame:Repositório Institucional da UFLA
instname:Universidade Federal de Lavras (UFLA)
instacron:UFLA
instname_str Universidade Federal de Lavras (UFLA)
instacron_str UFLA
institution UFLA
reponame_str Repositório Institucional da UFLA
collection Repositório Institucional da UFLA
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spelling 2018-08-01T20:04:42Z2018-08-01T20:04:42Z2017SIMÃO, A. A. et al. Aqueous extract of Psidium guajava leaves: phenolic compounds and inhibitory potential on digestive enzymes. Anais da Academia Brasileira de Ciências, Rio de Janeiro, v. 89, n. 3, p. 2155-2165, 2017. Suplemento 3.https://repositorio.ufla.br/handle/1/29864Leaves of Psidium guajava L. (guava) have been widely used in the popular way for prevention and treatment of various diseases. Thus, the objective of this study was to evaluate the inhibitory potential of leaves aqueous extract from three cultivars of P. guajava (Pedro Sato, Paluma and Século XXI) on α-amylase, α-glycosidase, lipase, and trypsin enzymes, in the presence or not of simulated gastric fluid and to determine the content of phenolic compounds by high performance liquid chromatography. All cultivars presented the same composition in phenolic compounds, but in different proportions. The compounds identified are gallic acid, epigallocatechin gallate, syringic acid, o-coumaric acid, resveratrol, quercetin, and catechin (which was the major compound in all the cultivars evaluated). In the absence of simulated gastric fluid, it was observed different inhibitions exercised by the leaves aqueous extracts from three cultivars of P. guajava on each enzyme. In presence of simulated gastric fluid, all cultivars showed increase in the inhibition of lipase and α-glycosidase, and decrease in inhibition of α-amylase and trypsin enzymes. These results indicate that P. guajava leaves aqueous extracts from all cultivars evaluated possess potential of use as an adjuvant in the treatment of obesity and other dyslipidemias.Academia Brasileira de CiênciasAttribution 4.0 Internationalhttp://creativecommons.org/licenses/by/4.0/info:eu-repo/semantics/openAccessAnais da Academia Brasileira de Ciênciasreponame:Repositório Institucional da UFLAinstname:Universidade Federal de Lavras (UFLA)instacron:UFLAMedicinal plantsObesityα-amylaseα-glycosidaseLipaseTrypsinAqueous extract of Psidium guajava leaves: phenolic compounds and inhibitory potential on digestive enzymesinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleengSimão, Anderson AssaidMarques, Tamara R.Marcussi, SilvanaCorrea, Angelita DuarteORIGINALARTIGO_Aqueous extract of Psidium guajava leaves- phenolic compounds and inhibitory potential on digestive enzymes.pdfARTIGO_Aqueous extract of Psidium guajava leaves- phenolic compounds and inhibitory potential on digestive enzymes.pdfapplication/pdf550317https://repositorio.ufla.br/bitstreams/9ff96a41-9869-4b1c-a7ea-b7e9bef408ad/downloadbcc36f4b8442471454a852a63c2b59d9MD51trueAnonymousREADCC-LICENSElicense_rdflicense_rdfapplication/rdf+xml; charset=utf-8907https://repositorio.ufla.br/bitstreams/253f532e-4f75-4c7d-9258-382922a9554d/downloadc07b6daef3dbee864bf87e6aa836cde2MD52falseAnonymousREADLICENSElicense.txtlicense.txttext/plain; charset=utf-8953https://repositorio.ufla.br/bitstreams/e2a5acfe-b802-4e1b-8aef-cbf928ae2768/download760884c1e72224de569e74f79eb87ce3MD53falseAnonymousREAD1/298642025-08-07 09:02:50.439http://creativecommons.org/licenses/by/4.0/Attribution 4.0 Internationalopen.accessoai:repositorio.ufla.br:1/29864https://repositorio.ufla.brRepositório InstitucionalPUBhttps://repositorio.ufla.br/server/oai/requestnivaldo@ufla.br || repositorio.biblioteca@ufla.bropendoar:2025-08-07T12:02:50Repositório Institucional da UFLA - Universidade Federal de Lavras (UFLA)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