Estudo de segurança de cosméticos: presente e futuro

Cosmetics have been used since ancient times and, recently, their consumption has increased greatly in many countries, including brazil, which is the third largest consumer market in the world. Thus, concern for the safety and efficacy of these products should be heightened, even though these produc...

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Detalles Bibliográficos
Autores: Chiari, Bruna Galdorfini, Magnani, Caroline [UNESP], Salgado, Hérida Regina Nunes [UNESP], Corrêa, Marcos Antônio [UNESP], Isaac, Vera Lucia Borges [UNESP]
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2012
País:Brasil
Institución:Universidade Estadual Paulista (UNESP)
Repositorio:Repositório Institucional da UNESP
Idioma:portugués
OAI Identifier:oai:repositorio.unesp.br:11449/133736
Acceso en línea:http://serv-bib.fcfar.unesp.br/seer/index.php/Cien_Farm/article/view/2161
http://hdl.handle.net/11449/133736
Access Level:acceso abierto
Palabra clave:Safety
Alternative methods
In vitro
Cosmetics
Segurança
Métodos alternativos
Cosméticos
Descripción
Sumario:Cosmetics have been used since ancient times and, recently, their consumption has increased greatly in many countries, including brazil, which is the third largest consumer market in the world. Thus, concern for the safety and efficacy of these products should be heightened, even though these products are rarely related to adverse reactions that damage the health. Brazilian law requires manufacturers to subject their products to safety testing, to assess the possible reactions that could be caused by them (irritation, sensitization, systemic effects). To this end, in general, animals have been used as the experimental model, but this practice is being increasingly controlled, so that the scientific community is looking for alternative tests that do not require experimental in vivo models. Thus, this review aims to describe the main biological assays used to assess the safety of cosmetics, as well as in vitro assays that can replace them.