Candidemia em hospital terciário do nordeste do Brasil

We conducted a prospective, observational, laboratory-based study on candidemia to investigate the incidence of candidemia, species distribution and clinical conditions between September 2003 and March 2004 in a private tertiary hospital in Recife, northeastern Brazil. Cases of candidemia were defin...

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Detalles Bibliográficos
Autores: Hinrichsen, Sylvia Lemos, Falcão, Érika, Vilella, Tatiana Aguiar Santos, Colombo, Arnaldo Lopes [UNIFESP], Nucci, Marcio, Moura, Líbia, Rêgo, Leandro, Lira, Conceição, Almeida, Luciano
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2008
País:Brasil
Institución:Universidade Federal de São Paulo (UNIFESP)
Repositorio:Repositório Institucional da UNIFESP
Idioma:portugués
OAI Identifier:oai:repositorio.unifesp.br:11600/4495
Acceso en línea:http://dx.doi.org/10.1590/S0037-86822008000400014
http://repositorio.unifesp.br/handle/11600/4495
Access Level:acceso abierto
Palabra clave:Candidemia
Candida species
Candida non-albicans
Incidence
Espécies de Candida
Candida não-albicans
Incidência
Descripción
Sumario:We conducted a prospective, observational, laboratory-based study on candidemia to investigate the incidence of candidemia, species distribution and clinical conditions between September 2003 and March 2004 in a private tertiary hospital in Recife, northeastern Brazil. Cases of candidemia were defined as occurrences of isolation of Candida spp from blood cultures. The incidence rate was calculated per 1,000 admissions. A total of 5,532 patients were admitted to the hospital during the study period, and 1,745 blood cultures were processed. Twenty-one episodes of candidemia were observed in 18 patients. The incidence rate of candidemia was 3.9 episodes per 1,000 admissions. Non-albicans species accounted for more than 50% of the cases, and Candida parapsilosis (33%) and Candida tropicalis (24%) predominated. Eleven (61%) patients died. The incidence of candidemia was higher than that observed in a Brazilian multicenter study. Candidemia was caused predominantly by non-albicans species.