Borderline personality features possibly related to cingulate and orbitofrontal cortices dysfunction due to schizencephaly.

Prefrontal cortex dysfunction has been associated with a series of behavioral symptoms, such as impulsivity and affective instability, which are the defining features of several personality disorders, notably, borderline personality disorder. We report on a 27-year-old patient with schizencephaly in...

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Detalhes bibliográficos
Autores: Rocha, Felipe Filardi da, Diniz, Leandro Malloy, Sousa, Karla Cristhina Alves de, Cano Prais, Hugo Alejandro, Correa, Humberto, Teixeira, Antônio Lúcio
Formato: artículo
Estado:Versión publicada
Fecha de publicación:2008
País:Brasil
Recursos:Universidade Federal de Ouro Preto (UFOP)
Repositorio:Repositório Institucional da UFOP
Idioma:inglés
OAI Identifier:oai:repositorio.ufop.br:123456789/3835
Acesso em linha:http://www.repositorio.ufop.br/handle/123456789/3835
https://doi.org/10.1016/j.clineuro.2007.12.009
Access Level:acceso abierto
Palavra-chave:Schizencephaly
Impulsivity
Borderline personality
Orbitofrontal cortex
Cingulate cortex
Descrição
Resumo:Prefrontal cortex dysfunction has been associated with a series of behavioral symptoms, such as impulsivity and affective instability, which are the defining features of several personality disorders, notably, borderline personality disorder. We report on a 27-year-old patient with schizencephaly in the right frontal lobe (cingulate cortex lesion and secondary orbitofrontal cortex dysfunction) presenting with prominent borderline features and compromise of executive functions, decision-making and attention. We hypothesize that the personality disorder of our patient could be related to cingulate cortex lesion and secondary orbitofrontal cortex dysfunction associated with schizencephaly.