Genetic diversity of NS5A protein from hepatitis C virus genotype 3a and its relationship to therapy response

Artur Trancoso Lopo de Queiroz “Documento produzido em parceria ou por autor vinculado à Fiocruz, mas não consta à informação no documento”.

Detalhes bibliográficos
Autores: Bittar, Cíntia, Jardim, Ana Carolina Gomes, Yamasaki, Lilian Hiromi Tomonari Yamasaki, Queiroz, Artur Trancoso Lopo de, Carareto, Claudia Maria Aparecida, Pinho, João Renato Rebello, Mello, Isabel Maria Vicente Guedes de Carvalho, Rahal, Paula
Tipo de documento: artigo
Estado:Versão publicada
Data de publicação:2010
País:Brasil
Recursos:Fundação Oswaldo Cruz (FIOCRUZ)
Repositório:Repositório Institucional da FIOCRUZ (ARCA)
Idioma:inglês
OAI Identifier:oai:arca.fiocruz.br:icict/19308
Acesso em linha:https://arca.fiocruz.br/handle/icict/19308
Access Level:Acceso aberto
Palavra-chave:Hepatite C Crônica
Genótipo
Doenças virais
RNA Viral
Variação genética
Hepacivirus
Humanos
Hepatitis C Chronic
Genotype
Antiviral Agents
Genetic Variation
Humans
Variação Genética
03 Saúde e Bem-Estar
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oai_identifier_str oai:arca.fiocruz.br:icict/19308
network_acronym_str BR
network_name_str Brasil
repository_id_str
dc.title.none.fl_str_mv Genetic diversity of NS5A protein from hepatitis C virus genotype 3a and its relationship to therapy response
title Genetic diversity of NS5A protein from hepatitis C virus genotype 3a and its relationship to therapy response
spellingShingle Genetic diversity of NS5A protein from hepatitis C virus genotype 3a and its relationship to therapy response
Bittar, Cíntia
Hepatite C Crônica
Genótipo
Doenças virais
RNA Viral
Variação genética
Hepacivirus
Humanos
Hepatitis C Chronic
Genotype
Antiviral Agents
RNA Viral
Genetic Variation
Hepacivirus
Humans
Hepatite C Crônica
Genótipo
Doenças virais
RNA Viral
Variação Genética
Hepacivirus
Humanos
03 Saúde e Bem-Estar
title_short Genetic diversity of NS5A protein from hepatitis C virus genotype 3a and its relationship to therapy response
title_full Genetic diversity of NS5A protein from hepatitis C virus genotype 3a and its relationship to therapy response
title_fullStr Genetic diversity of NS5A protein from hepatitis C virus genotype 3a and its relationship to therapy response
title_full_unstemmed Genetic diversity of NS5A protein from hepatitis C virus genotype 3a and its relationship to therapy response
title_sort Genetic diversity of NS5A protein from hepatitis C virus genotype 3a and its relationship to therapy response
dc.creator.none.fl_str_mv Bittar, Cíntia
Jardim, Ana Carolina Gomes
Yamasaki, Lilian Hiromi Tomonari Yamasaki
Queiroz, Artur Trancoso Lopo de
Carareto, Claudia Maria Aparecida
Pinho, João Renato Rebello
Mello, Isabel Maria Vicente Guedes de Carvalho
Rahal, Paula
author Bittar, Cíntia
author_facet Bittar, Cíntia
Jardim, Ana Carolina Gomes
Yamasaki, Lilian Hiromi Tomonari Yamasaki
Queiroz, Artur Trancoso Lopo de
Carareto, Claudia Maria Aparecida
Pinho, João Renato Rebello
Mello, Isabel Maria Vicente Guedes de Carvalho
Rahal, Paula
author_role author
author2 Jardim, Ana Carolina Gomes
Yamasaki, Lilian Hiromi Tomonari Yamasaki
Queiroz, Artur Trancoso Lopo de
Carareto, Claudia Maria Aparecida
Pinho, João Renato Rebello
Mello, Isabel Maria Vicente Guedes de Carvalho
Rahal, Paula
author2_role author
author
author
author
author
author
author
dc.subject.other.none.fl_str_mv Hepatite C Crônica
Genótipo
Doenças virais
RNA Viral
Variação genética
Hepacivirus
Humanos
topic Hepatite C Crônica
Genótipo
Doenças virais
RNA Viral
Variação genética
Hepacivirus
Humanos
Hepatitis C Chronic
Genotype
Antiviral Agents
RNA Viral
Genetic Variation
Hepacivirus
Humans
Hepatite C Crônica
Genótipo
Doenças virais
RNA Viral
Variação Genética
Hepacivirus
Humanos
03 Saúde e Bem-Estar
dc.subject.en.none.fl_str_mv Hepatitis C Chronic
Genotype
Antiviral Agents
RNA Viral
Genetic Variation
Hepacivirus
Humans
dc.subject.decs.none.fl_str_mv Hepatite C Crônica
Genótipo
Doenças virais
RNA Viral
Variação Genética
Hepacivirus
Humanos
dc.subject.ods.none.fl_str_mv 03 Saúde e Bem-Estar
description Artur Trancoso Lopo de Queiroz “Documento produzido em parceria ou por autor vinculado à Fiocruz, mas não consta à informação no documento”.
publishDate 2010
dc.date.issued.fl_str_mv 2010
dc.date.accessioned.fl_str_mv 2017-06-06T12:26:18Z
dc.date.available.fl_str_mv 2017-06-06T12:26:18Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.citation.fl_str_mv BITTAR, C. et al. Genetic diversity of NS5A protein from hepatitis C virus genotype 3a and its relationship to therapy response. BMC Infectious Diseases, v. 10, p. 36, 2010
dc.identifier.uri.fl_str_mv https://arca.fiocruz.br/handle/icict/19308
dc.identifier.issn.none.fl_str_mv 1471-2334
dc.identifier.doi.none.fl_str_mv 10.1186/1471-2334-10-36
identifier_str_mv BITTAR, C. et al. Genetic diversity of NS5A protein from hepatitis C virus genotype 3a and its relationship to therapy response. BMC Infectious Diseases, v. 10, p. 36, 2010
1471-2334
10.1186/1471-2334-10-36
url https://arca.fiocruz.br/handle/icict/19308
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv BioMed Central
publisher.none.fl_str_mv BioMed Central
dc.source.none.fl_str_mv reponame:Repositório Institucional da FIOCRUZ (ARCA)
instname:Fundação Oswaldo Cruz (FIOCRUZ)
instacron:FIOCRUZ
instname_str Fundação Oswaldo Cruz (FIOCRUZ)
instacron_str FIOCRUZ
institution FIOCRUZ
reponame_str Repositório Institucional da FIOCRUZ (ARCA)
collection Repositório Institucional da FIOCRUZ (ARCA)
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spelling 2017-06-06T12:26:18Z2017-06-06T12:26:18Z2010BITTAR, C. et al. Genetic diversity of NS5A protein from hepatitis C virus genotype 3a and its relationship to therapy response. BMC Infectious Diseases, v. 10, p. 36, 20101471-2334https://arca.fiocruz.br/handle/icict/1930810.1186/1471-2334-10-36Artur Trancoso Lopo de Queiroz “Documento produzido em parceria ou por autor vinculado à Fiocruz, mas não consta à informação no documento”.FAPESP and CAPES.São Paulo State University. Institute of Bioscience, Language & Literature and Exact Science. Department of Biology. São Paulo, SP, BrasilSão Paulo State University. Institute of Bioscience, Language & Literature and Exact Science. Department of Biology. São Paulo, SP, BrasilSão Paulo State University. Institute of Bioscience, Language & Literature and Exact Science. Department of Biology. São Paulo, SP, BrasilSão Paulo University. São Paulo, SP, BrazilSão Paulo State University. Institute of Bioscience, Language & Literature and Exact Science. Department of Biology. São Paulo, SP, BrasilSão Paulo University. Faculty of Medicine. Institute of Tropical Medicine. Department of Gastroenterology. Laboratory of Hepatology and Gastroenterology. São Paulo, SP, Brazil / Albert Einstein Israeli Hospital. Department of Clinical Pathology. São Paulo, SP, BrazilButantan Institute. Viral Immunology Laboratory. Butantã, São Paulo, SP, BrazilSão Paulo State University. Institute of Bioscience, Language & Literature and Exact Science. Department of Biology. São Paulo, SP, BrasilThe quasispecies nature of HCV may have important implications for viral persistence, pathogenicity and resistance to antiviral agents. The variability of one of the viral proteins, NS5A, is believed to be related to the response to IFN therapy, the standard treatment for infection. In this study we analyzed the quasispecies composition of NS5A protein in patients infected with HCV genotype 3a, before IFN therapy.engBioMed CentralHepatite C CrônicaGenótipoDoenças viraisRNA ViralVariação genéticaHepacivirusHumanosHepatitis C ChronicGenotypeAntiviral AgentsRNA ViralGenetic VariationHepacivirusHumansHepatite C CrônicaGenótipoDoenças viraisRNA ViralVariação GenéticaHepacivirusHumanos03 Saúde e Bem-EstarGenetic diversity of NS5A protein from hepatitis C virus genotype 3a and its relationship to therapy responseinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZBittar, CíntiaJardim, Ana Carolina GomesYamasaki, Lilian Hiromi Tomonari YamasakiQueiroz, Artur Trancoso Lopo deCarareto, Claudia Maria AparecidaPinho, João Renato RebelloMello, Isabel Maria Vicente Guedes de CarvalhoRahal, PaulaLICENSElicense.txtlicense.txttext/plain; charset=utf-82991https://arca.fiocruz.br/bitstreams/1e6c3865-c221-4452-8f87-e827226da319/download5a560609d32a3863062d77ff32785d58MD51falseAnonymousREADORIGINALBittar C Genetic diversity....pdfBittar C Genetic diversity....pdfapplication/pdf981189https://arca.fiocruz.br/bitstreams/af429180-92a6-4e67-a430-d01480f17c06/download6096057d15d5a1147f1b96ded30d1ec8MD52trueAnonymousREADTEXTBittar C Genetic diversity....pdf.txtBittar C Genetic diversity....pdf.txtExtracted texttext/plain47782https://arca.fiocruz.br/bitstreams/55cf740d-c4c0-4613-bc30-e1b39c0f8c06/download6e2a0450664e95f0d8c72398db9c007fMD57falseAnonymousREADTHUMBNAILBittar C Genetic diversity....pdf.jpgBittar C Genetic diversity....pdf.jpgGenerated Thumbnailimage/jpeg43092https://arca.fiocruz.br/bitstreams/243f3b14-0a7f-4f9f-ab97-d61345ddd29e/download0df7d9d313902ed749b245d65e1ace91MD58falseAnonymousREADicict/193082025-12-10 14:30:22.56open.accessoai:arca.fiocruz.br:icict/19308https://arca.fiocruz.brRepositório InstitucionalPUBhttps://www.arca.fiocruz.br/oai/requestrepositorio.arca@fiocruz.bropendoar:21352025-12-10T17:30:22Repositório Institucional da FIOCRUZ (ARCA) - 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