Non-functioning paraganglioma of the bladder: case report and literature review

Introduction: Paragangliomas are pheochromocytomas with an extra-adrenal location. They can be found between the base of the skull and the bladder. They account for less than 0.06% of all bladder tumors, and were first reported by Zimmermann in 1953, and Rodriguez-Rubio in 1975. Case report: A 17 ye...

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Autores: Silva, Ulysses Messias da, Manteuffel, Ricardo Alexandre, Serapião, Mônica, Sedrez, Roberto Carlos
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2004
País:Brasil
Institución:Instituto Nacional de Câncer José Alencar Gomes da Silva (INCA)
Repositorio:Revista Brasileira de Cancerologia (Online)
Idioma:portugués
OAI Identifier:oai:rbc.inca.gov.br:article/2028
Acceso en línea:https://rbc.inca.gov.br/index.php/revista/article/view/2028
Access Level:acceso abierto
Palabra clave:Paraganglioma
Neoplasias da bexiga
Feocromocitoma
Tumor vesical
Bladder neoplasms
Pheochromocytoma
Vesical tumor
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dc.title.none.fl_str_mv Non-functioning paraganglioma of the bladder: case report and literature review
Paraganglioma não-funcionante de bexiga: relato de caso e revisão da literatura
title Non-functioning paraganglioma of the bladder: case report and literature review
spellingShingle Non-functioning paraganglioma of the bladder: case report and literature review
Silva, Ulysses Messias da
Paraganglioma
Neoplasias da bexiga
Feocromocitoma
Tumor vesical
Paraganglioma
Bladder neoplasms
Pheochromocytoma
Vesical tumor
title_short Non-functioning paraganglioma of the bladder: case report and literature review
title_full Non-functioning paraganglioma of the bladder: case report and literature review
title_fullStr Non-functioning paraganglioma of the bladder: case report and literature review
title_full_unstemmed Non-functioning paraganglioma of the bladder: case report and literature review
title_sort Non-functioning paraganglioma of the bladder: case report and literature review
dc.creator.none.fl_str_mv Silva, Ulysses Messias da
Manteuffel, Ricardo Alexandre
Serapião, Mônica
Sedrez, Roberto Carlos
author Silva, Ulysses Messias da
author_facet Silva, Ulysses Messias da
Manteuffel, Ricardo Alexandre
Serapião, Mônica
Sedrez, Roberto Carlos
author_role author
author2 Manteuffel, Ricardo Alexandre
Serapião, Mônica
Sedrez, Roberto Carlos
author2_role author
author
author
dc.subject.por.fl_str_mv Paraganglioma
Neoplasias da bexiga
Feocromocitoma
Tumor vesical
Paraganglioma
Bladder neoplasms
Pheochromocytoma
Vesical tumor
topic Paraganglioma
Neoplasias da bexiga
Feocromocitoma
Tumor vesical
Paraganglioma
Bladder neoplasms
Pheochromocytoma
Vesical tumor
description Introduction: Paragangliomas are pheochromocytomas with an extra-adrenal location. They can be found between the base of the skull and the bladder. They account for less than 0.06% of all bladder tumors, and were first reported by Zimmermann in 1953, and Rodriguez-Rubio in 1975. Case report: A 17 year old male patient was admitted to Alto Vale Regional Hospital with hematuria and urinary retention. He was examined but nothing positive was found, after which he was discharged for outpatient treatment. After the vesical tumor was diagnosed, the patient was admitted to Hospital for elective surgical treatment of the tumor. After this, pathological analysis revealed a paraganglioma, confirmed by immunohistochemistry. Eleven months after surgery, the patient remains healthy and assymptomatic. Discussion: Paragangliomas usually appear between 11 and 70 years, and are clinically classified as functioning or non-functioning depending on cathecolaminergic production by the tumor. Ten to fifteen percent of bladder paragangliomas are malignant. The diagnosis is confirmed by urinary vanilmandelic acid and urinary metanephryns, ultrassonography, excretory urography, cistoscopy, computerized tomography, magnetic nuclear resonance, and 131-metaiodobenzilguanidine iodine cintilography, with the last one being the most sensitive according to the literature. The treatment is surgical, and the prognosis is uncertain due to small number of cases reported.
publishDate 2004
dc.date.none.fl_str_mv 2004-09-30
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
Relato de Caso
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://rbc.inca.gov.br/index.php/revista/article/view/2028
10.32635/2176-9745.RBC.2004v50n3.2028
url https://rbc.inca.gov.br/index.php/revista/article/view/2028
identifier_str_mv 10.32635/2176-9745.RBC.2004v50n3.2028
dc.language.iso.fl_str_mv por
language por
dc.relation.none.fl_str_mv https://rbc.inca.gov.br/index.php/revista/article/view/2028/1249
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv INCA
publisher.none.fl_str_mv INCA
dc.source.none.fl_str_mv Revista Brasileira de Cancerologia; Vol. 50 No. 3 (2004): July/Aug./Sept; 227-232
Revista Brasileira de Cancerologia; Vol. 50 Núm. 3 (2004): jul./ago/sept.; 227-232
Revista Brasileira de Cancerologia; v. 50 n. 3 (2004): jul./ago.set.; 227-232
2176-9745
reponame:Revista Brasileira de Cancerologia (Online)
instname:Instituto Nacional de Câncer José Alencar Gomes da Silva (INCA)
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instname_str Instituto Nacional de Câncer José Alencar Gomes da Silva (INCA)
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reponame_str Revista Brasileira de Cancerologia (Online)
collection Revista Brasileira de Cancerologia (Online)
repository.name.fl_str_mv Revista Brasileira de Cancerologia (Online) - Instituto Nacional de Câncer José Alencar Gomes da Silva (INCA)
repository.mail.fl_str_mv rbc@inca.gov.br
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spelling Non-functioning paraganglioma of the bladder: case report and literature reviewParaganglioma não-funcionante de bexiga: relato de caso e revisão da literaturaParagangliomaNeoplasias da bexigaFeocromocitomaTumor vesicalParagangliomaBladder neoplasmsPheochromocytomaVesical tumorIntroduction: Paragangliomas are pheochromocytomas with an extra-adrenal location. They can be found between the base of the skull and the bladder. They account for less than 0.06% of all bladder tumors, and were first reported by Zimmermann in 1953, and Rodriguez-Rubio in 1975. Case report: A 17 year old male patient was admitted to Alto Vale Regional Hospital with hematuria and urinary retention. He was examined but nothing positive was found, after which he was discharged for outpatient treatment. After the vesical tumor was diagnosed, the patient was admitted to Hospital for elective surgical treatment of the tumor. After this, pathological analysis revealed a paraganglioma, confirmed by immunohistochemistry. Eleven months after surgery, the patient remains healthy and assymptomatic. Discussion: Paragangliomas usually appear between 11 and 70 years, and are clinically classified as functioning or non-functioning depending on cathecolaminergic production by the tumor. Ten to fifteen percent of bladder paragangliomas are malignant. The diagnosis is confirmed by urinary vanilmandelic acid and urinary metanephryns, ultrassonography, excretory urography, cistoscopy, computerized tomography, magnetic nuclear resonance, and 131-metaiodobenzilguanidine iodine cintilography, with the last one being the most sensitive according to the literature. The treatment is surgical, and the prognosis is uncertain due to small number of cases reported.Introdução: Os paragangliomas são feocromocitomas de localização extra-adrenal, podendo ser encontrados desde a base do crânio até a bexiga. Representam menos de 0,06% de todos os tumores da bexiga, sendo os primeiros casos publicados por Zimmermann em 1953, e por Rodriguez-Rubio em 1975. Relato do caso: Paciente de 17 anos, masculino, deu entrada no Hospital Regional Alto Vale apresentando hematúria e retenção urinária. Foi investigado sem achados positivos, tendo recebido alta hospitalar para investigação ambulatorial do quadro. Diagnosticado o tumor vesical ambulatorialmente, o paciente foi internado para tratamento cirúrgico eletivo do tumor, cujo exame anátomo-patológico revelou a presença de um paraganglioma, confirmado após imunohistoquímica. Onze meses após a cirurgia o paciente permanece hígido e assintomático. Discussão: A idade de apresentação oscila entre os 11 e os 70 anos. Clinicamente são classificados em funcionantes e não-funcionantes de acordo com a presença de produção catecolaminérgica pela neoplasia. Dez a quinze por cento dos paragangliomas de bexiga são malignos. O diagnóstico é confirmado pela dosagem do Ácido Vanilmandélico e Metanefrinas urinárias, Ultrassonografia, Urografia Excretora, Cistoscopia, Tomografia Computadorizada, Ressonância Nuclear Magnética e a Cintilografia com Iodo 131-Metaiodobenzilguanidina, sendo este último apontado como o mais sensível pela literatura. O tratamento é cirúrgico, e o prognóstico ainda é uma incógnita devido ao ainda pequeno número de casos relatados.INCA2004-09-30info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionRelato de Casoapplication/pdfhttps://rbc.inca.gov.br/index.php/revista/article/view/202810.32635/2176-9745.RBC.2004v50n3.2028Revista Brasileira de Cancerologia; Vol. 50 No. 3 (2004): July/Aug./Sept; 227-232Revista Brasileira de Cancerologia; Vol. 50 Núm. 3 (2004): jul./ago/sept.; 227-232Revista Brasileira de Cancerologia; v. 50 n. 3 (2004): jul./ago.set.; 227-2322176-9745reponame:Revista Brasileira de Cancerologia (Online)instname:Instituto Nacional de Câncer José Alencar Gomes da Silva (INCA)instacron:INCAporhttps://rbc.inca.gov.br/index.php/revista/article/view/2028/1249info:eu-repo/semantics/openAccessSilva, Ulysses Messias da Manteuffel, Ricardo Alexandre Serapião, Mônica Sedrez, Roberto Carlos 2021-11-29T20:32:32Zoai:rbc.inca.gov.br:article/2028Revistahttps://rbc.inca.gov.br/index.php/revistaPUBhttps://rbc.inca.gov.br/index.php/revista/oairbc@inca.gov.br0034-71162176-9745opendoar:2021-11-29T20:32:32Revista Brasileira de Cancerologia (Online) - Instituto Nacional de Câncer José Alencar Gomes da Silva (INCA)false
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