Arterioplastia com enxerto de pericárdio bovino: estudo experimental em cães

The aim of this work was to evaluate the efficacy of bovine pericardium (BP) patch graft to treat arterial defects created in the femoral artery of dogs, compared to the cephalic vein autograft (CVA) on both side of the arteries. Twenty mongrel dogs (eight males and twelve females), were used and di...

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Detalles Bibliográficos
Autores: Costa, Regina de Faria Bittencourt da [UNIFESP], Nigro, Amaury José Teixeira [UNIFESP], Vieira, Wilma Therezinha Trench
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:1997
País:Brasil
Institución:Universidade Federal de São Paulo (UNIFESP)
Repositorio:Repositório Institucional da UNIFESP
Idioma:portugués
OAI Identifier:oai:repositorio.unifesp.br:11600/489
Acceso en línea:http://dx.doi.org/10.1590/S0102-86501997000200007
http://repositorio.unifesp.br/handle/11600/489
Access Level:acceso abierto
Palabra clave:Bioprosthesis
Femoral artery
Pericardium
Vein
Dogs
Biopróteses
Artéria Femoral
Pericárdio
Veia
Cães
Descripción
Sumario:The aim of this work was to evaluate the efficacy of bovine pericardium (BP) patch graft to treat arterial defects created in the femoral artery of dogs, compared to the cephalic vein autograft (CVA) on both side of the arteries. Twenty mongrel dogs (eight males and twelve females), were used and disbuted in two groups of ten animals (I and II), to be re-operated on 7th and 30th post operative days, respstively. Clinical and histolgical data analysis were done using the chi-square an exact Fisher test (a£ 0,05). Significant alterations wasn't found in the clinical examinations, independetly, of the kin of graft used and post operative observation period. It wasn't found any significant difference between the BP and CVA grafts in the histological analyses concerning the presence of inflammatory cell infiltration and mural thrombi that predominated on the 7th post operative day. Whilst, the presence of granulation tisseu, myofibroblastic plaque and endothelization predominated on the 30th post operative day. The presence of necrosis was found significant for both BP and CVA, on the 7th post operative day, being higher for BP. Calcification of the grafts was not observed. A significant reaction of strange body kind to the polypropylene yarn take place on the 30th PO for both grafts. These results sugested that BP was efficient as artery substitute for dogs, which was comparable to CVA, for the settled period of observation.