Comparative evaluation of the effects of epidural morphine and 0.9% sodium chloride on cardiorespiratory function and anesthetic recovery in ponies

Epidural analgesia is an effective technique to treat acute and chronic pain as well as to provide preemptive, intraoperative, and postoperative analgesia. This study was performed to evaluate the effects of epidurally injected morphine and a control group that received 0.9% sodium chloride. Eightee...

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Autores: Natalini, Cláudio Corrêa, Crosignani, Nadia, Polidoro, Alexandre da Silva
Tipo de documento: artigo
Estado:Versão publicada
Data de publicação:2018
País:Brasil
Recursos:Universidade Federal do Rio Grande do Sul (UFRGS)
Repositório:Revista Acta Scientiae Veterinariae (Online)
Idioma:português
OAI Identifier:oai:seer.ufrgs.br:article/16122
Acesso em linha:https://seer.ufrgs.br/index.php/ActaScientiaeVeterinariae/article/view/16122
Access Level:Acceso aberto
Palavra-chave:Epidural
Morfina
Pôneis
Analgesia
Halotano
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spelling Comparative evaluation of the effects of epidural morphine and 0.9% sodium chloride on cardiorespiratory function and anesthetic recovery in poniesEpiduralMorfinaPôneisAnalgesiaHalotanoEpidural analgesia is an effective technique to treat acute and chronic pain as well as to provide preemptive, intraoperative, and postoperative analgesia. This study was performed to evaluate the effects of epidurally injected morphine and a control group that received 0.9% sodium chloride. Eighteen healthy male adult ponies were studied. Two groups of 9 were formed. Group M (morphine) received 0.1mg/kg morphine diluted up to 5ml in sterile water, injected at the first intercoccygeal intervertebral space. Group S (saline) received 5ml of sterile 0.9% sodium chloride. All animals received 1mg/kg xylazine IV for sedation, were induced with 5% guaifenesin at 55mg/kg and 5% thiopental sodium at 4mg/kg IV, and maintained with halothane. Orthopedic surgeries on the thoracic limb (desmotomy) and on the pelvic limb (total ostectomy of the metatarsal II bone) were performed. After anesthesia induction, heart rate, respiratory rate, and arterial blood pressure recorded at 15 minutes intervals, for 90 minutes. Recovery times were recorded beginning when the administration of halothane was interrupted. Recovery quality was graded and compared between groups. Data was analyzed with two-way ANOVA and Bonferroni’s test, and ANOVA on ranks. Results demonstrated that recovery time was significantly shorter for the saline group, although the recovery quality was better for the morphine group. Epidural morphine does not produce surgical analgesia for the thoracic limbs in ponies. However it does produce for the pelvic limbs. Epidural morphine in ponies produces superior recovery quality when halothane is used as an inhalant anesthetic.Universidade Federal do Rio Grande do Sul2018-06-27info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://seer.ufrgs.br/index.php/ActaScientiaeVeterinariae/article/view/1612210.22456/1679-9216.16122Acta Scientiae Veterinariae; Vol. 35 No. 3 (2007); 315-320Acta Scientiae Veterinariae; v. 35 n. 3 (2007); 315-3201679-9216reponame:Revista Acta Scientiae Veterinariae (Online)instname:Universidade Federal do Rio Grande do Sul (UFRGS)instacron:UFRGSporhttps://seer.ufrgs.br/index.php/ActaScientiaeVeterinariae/article/view/16122/9543Copyright (c) 2018 Cláudio Corrêa Natalini, Nadia Crosignani, Alexandre da Silva Polidoroinfo:eu-repo/semantics/openAccessNatalini, Cláudio CorrêaCrosignani, NadiaPolidoro, Alexandre da Silva2018-06-27T15:08:57Zoai:seer.ufrgs.br:article/16122Revistahttps://seer.ufrgs.br/index.php/ActaScientiaeVeterinariae/oaiPUBhttps://seer.ufrgs.br/index.php/ActaScientiaeVeterinariae/indexquestions-acta@ufrgs.br1679-92161678-0345opendoar:2018-06-27T15:08:57Revista Acta Scientiae Veterinariae (Online) - Universidade Federal do Rio Grande do Sul (UFRGS)false
dc.title.none.fl_str_mv Comparative evaluation of the effects of epidural morphine and 0.9% sodium chloride on cardiorespiratory function and anesthetic recovery in ponies
title Comparative evaluation of the effects of epidural morphine and 0.9% sodium chloride on cardiorespiratory function and anesthetic recovery in ponies
spellingShingle Comparative evaluation of the effects of epidural morphine and 0.9% sodium chloride on cardiorespiratory function and anesthetic recovery in ponies
Natalini, Cláudio Corrêa
Epidural
Morfina
Pôneis
Analgesia
Halotano
title_short Comparative evaluation of the effects of epidural morphine and 0.9% sodium chloride on cardiorespiratory function and anesthetic recovery in ponies
title_full Comparative evaluation of the effects of epidural morphine and 0.9% sodium chloride on cardiorespiratory function and anesthetic recovery in ponies
title_fullStr Comparative evaluation of the effects of epidural morphine and 0.9% sodium chloride on cardiorespiratory function and anesthetic recovery in ponies
title_full_unstemmed Comparative evaluation of the effects of epidural morphine and 0.9% sodium chloride on cardiorespiratory function and anesthetic recovery in ponies
title_sort Comparative evaluation of the effects of epidural morphine and 0.9% sodium chloride on cardiorespiratory function and anesthetic recovery in ponies
dc.creator.none.fl_str_mv Natalini, Cláudio Corrêa
Crosignani, Nadia
Polidoro, Alexandre da Silva
author Natalini, Cláudio Corrêa
author_facet Natalini, Cláudio Corrêa
Crosignani, Nadia
Polidoro, Alexandre da Silva
author_role author
author2 Crosignani, Nadia
Polidoro, Alexandre da Silva
author2_role author
author
dc.subject.por.fl_str_mv Epidural
Morfina
Pôneis
Analgesia
Halotano
topic Epidural
Morfina
Pôneis
Analgesia
Halotano
description Epidural analgesia is an effective technique to treat acute and chronic pain as well as to provide preemptive, intraoperative, and postoperative analgesia. This study was performed to evaluate the effects of epidurally injected morphine and a control group that received 0.9% sodium chloride. Eighteen healthy male adult ponies were studied. Two groups of 9 were formed. Group M (morphine) received 0.1mg/kg morphine diluted up to 5ml in sterile water, injected at the first intercoccygeal intervertebral space. Group S (saline) received 5ml of sterile 0.9% sodium chloride. All animals received 1mg/kg xylazine IV for sedation, were induced with 5% guaifenesin at 55mg/kg and 5% thiopental sodium at 4mg/kg IV, and maintained with halothane. Orthopedic surgeries on the thoracic limb (desmotomy) and on the pelvic limb (total ostectomy of the metatarsal II bone) were performed. After anesthesia induction, heart rate, respiratory rate, and arterial blood pressure recorded at 15 minutes intervals, for 90 minutes. Recovery times were recorded beginning when the administration of halothane was interrupted. Recovery quality was graded and compared between groups. Data was analyzed with two-way ANOVA and Bonferroni’s test, and ANOVA on ranks. Results demonstrated that recovery time was significantly shorter for the saline group, although the recovery quality was better for the morphine group. Epidural morphine does not produce surgical analgesia for the thoracic limbs in ponies. However it does produce for the pelvic limbs. Epidural morphine in ponies produces superior recovery quality when halothane is used as an inhalant anesthetic.
publishDate 2018
dc.date.none.fl_str_mv 2018-06-27
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://seer.ufrgs.br/index.php/ActaScientiaeVeterinariae/article/view/16122
10.22456/1679-9216.16122
url https://seer.ufrgs.br/index.php/ActaScientiaeVeterinariae/article/view/16122
identifier_str_mv 10.22456/1679-9216.16122
dc.language.iso.fl_str_mv por
language por
dc.relation.none.fl_str_mv https://seer.ufrgs.br/index.php/ActaScientiaeVeterinariae/article/view/16122/9543
dc.rights.driver.fl_str_mv Copyright (c) 2018 Cláudio Corrêa Natalini, Nadia Crosignani, Alexandre da Silva Polidoro
info:eu-repo/semantics/openAccess
rights_invalid_str_mv Copyright (c) 2018 Cláudio Corrêa Natalini, Nadia Crosignani, Alexandre da Silva Polidoro
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Universidade Federal do Rio Grande do Sul
publisher.none.fl_str_mv Universidade Federal do Rio Grande do Sul
dc.source.none.fl_str_mv Acta Scientiae Veterinariae; Vol. 35 No. 3 (2007); 315-320
Acta Scientiae Veterinariae; v. 35 n. 3 (2007); 315-320
1679-9216
reponame:Revista Acta Scientiae Veterinariae (Online)
instname:Universidade Federal do Rio Grande do Sul (UFRGS)
instacron:UFRGS
instname_str Universidade Federal do Rio Grande do Sul (UFRGS)
instacron_str UFRGS
institution UFRGS
reponame_str Revista Acta Scientiae Veterinariae (Online)
collection Revista Acta Scientiae Veterinariae (Online)
repository.name.fl_str_mv Revista Acta Scientiae Veterinariae (Online) - Universidade Federal do Rio Grande do Sul (UFRGS)
repository.mail.fl_str_mv questions-acta@ufrgs.br
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score 15,301629

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