Correlation between late cord clamping and phototherapy and other neonatal unfavorable outcomes : a randomized clinical trial

Background: Recently, late umbilical cord clamping is generally recommended, which decreases neonatal anemia; however, it may also increase neonatal jaundice and some other poor outcomes. Objectives: We here attempted to determine whether late clamping actually increases the incidence of phototherap...

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Autores: Vettorazzi, Janete, Rostirolla, Gabriela Françoes, Zanatta, Maria Alexandrina, Valério, Edimárlei Gonsales, Ferreira, Charles Francisco, Ramos, José Geraldo Lopes
Tipo de documento: artigo
Estado:Versão publicada
Data de publicação:2022
País:Brasil
Recursos:Universidade Federal do Rio Grande do Sul (UFRGS)
Repositório:Repositório Institucional da UFRGS
Idioma:inglês
OAI Identifier:oai:www.lume.ufrgs.br:10183/237152
Acesso em linha:http://hdl.handle.net/10183/237152
Access Level:Acceso aberto
Palavra-chave:Fototerapia
Anemia neonatal
Icterícia neonatal
Constrição
Cordão umbilical
Recém-nascido
Phototherapy
Neonatal anemia
Neonatal jaundice
Late cord clamping
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spelling 2022-04-13T04:51:36Z20222160-8806http://hdl.handle.net/10183/237152001139443Background: Recently, late umbilical cord clamping is generally recommended, which decreases neonatal anemia; however, it may also increase neonatal jaundice and some other poor outcomes. Objectives: We here attempted to determine whether late clamping actually increases the incidence of phototherapy for jaundice and other poor outcomes of the term “low-risk newborns”. Methods: With the approval of the Brazilian Registry of Clinical Trials (REBEC), a total of 357 low-risk newborns (singleton, uncomplicated pregnancy/delivery, in a Brazilian public institution) were randomized into two groups: group I (n = 114): cord clamping < 1 minute (early clamping) or group II (n = 243): cord clamping between 1 - 3 minutes (late clamping). Statistics were used appropriately (i.e., measures of central tendency, dispersion for continuous variables, Shapiro-Wilk, Mann-Whitney test, or Chi-square test). Results: Phototherapy was performed in 5.3% in both groups. Also, there were no statistical differences in the occurrence of secondary outcomes, such as sepsis, neonatal ICU admission, and transient tachypnea of the newborns: i.e., 0.9%, 15.8%, and 3.5%, respectively for group I versus 1.2%, 15.6%, and 5.8%, respectively for group II. Conclusion: Late umbilical cord clamping does not increase the need for phototherapy in low-risk neonates. This result corroborates the current recommendation of late cord clamping, whenever appropriate.application/pdfengOpen journal of obstetrics and gynecology. Irvine. Vol. 12, no. 3 (2022), p. 193-200.FototerapiaAnemia neonatalIcterícia neonatalConstriçãoCordão umbilicalRecém-nascidoPhototherapyNeonatal anemiaNeonatal jaundiceLate cord clampingCorrelation between late cord clamping and phototherapy and other neonatal unfavorable outcomes : a randomized clinical trialEstrangeiroinfo:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da UFRGSinstname:Universidade Federal do Rio Grande do Sul (UFRGS)instacron:UFRGSVettorazzi, JaneteRostirolla, Gabriela FrançoesZanatta, Maria AlexandrinaValério, Edimárlei GonsalesFerreira, Charles FranciscoRamos, José Geraldo LopesTEXT001139443.pdf.txt001139443.pdf.txtExtracted Texttext/plain20832http://www.lume.ufrgs.br/bitstream/10183/237152/2/001139443.pdf.txt50322ed678bd60caafeaec6414f4d7baMD52ORIGINAL001139443.pdfTexto completo (inglês)application/pdf787306http://www.lume.ufrgs.br/bitstream/10183/237152/1/001139443.pdf373c1194b14315ed48d117195f0b304eMD5110183/2371522022-04-20 04:52:31.2996oai:www.lume.ufrgs.br:10183/237152Repositório InstitucionalPUBhttps://lume.ufrgs.br/oai/requestlume@ufrgs.bropendoar:2022-04-20T07:52:31Repositório Institucional da UFRGS - Universidade Federal do Rio Grande do Sul (UFRGS)false
dc.title.pt_BR.fl_str_mv Correlation between late cord clamping and phototherapy and other neonatal unfavorable outcomes : a randomized clinical trial
title Correlation between late cord clamping and phototherapy and other neonatal unfavorable outcomes : a randomized clinical trial
spellingShingle Correlation between late cord clamping and phototherapy and other neonatal unfavorable outcomes : a randomized clinical trial
Vettorazzi, Janete
Fototerapia
Anemia neonatal
Icterícia neonatal
Constrição
Cordão umbilical
Recém-nascido
Phototherapy
Neonatal anemia
Neonatal jaundice
Late cord clamping
title_short Correlation between late cord clamping and phototherapy and other neonatal unfavorable outcomes : a randomized clinical trial
title_full Correlation between late cord clamping and phototherapy and other neonatal unfavorable outcomes : a randomized clinical trial
title_fullStr Correlation between late cord clamping and phototherapy and other neonatal unfavorable outcomes : a randomized clinical trial
title_full_unstemmed Correlation between late cord clamping and phototherapy and other neonatal unfavorable outcomes : a randomized clinical trial
title_sort Correlation between late cord clamping and phototherapy and other neonatal unfavorable outcomes : a randomized clinical trial
dc.creator.none.fl_str_mv Vettorazzi, Janete
Rostirolla, Gabriela Françoes
Zanatta, Maria Alexandrina
Valério, Edimárlei Gonsales
Ferreira, Charles Francisco
Ramos, José Geraldo Lopes
author Vettorazzi, Janete
author_facet Vettorazzi, Janete
Rostirolla, Gabriela Françoes
Zanatta, Maria Alexandrina
Valério, Edimárlei Gonsales
Ferreira, Charles Francisco
Ramos, José Geraldo Lopes
author_role author
author2 Rostirolla, Gabriela Françoes
Zanatta, Maria Alexandrina
Valério, Edimárlei Gonsales
Ferreira, Charles Francisco
Ramos, José Geraldo Lopes
author2_role author
author
author
author
author
dc.subject.por.fl_str_mv Fototerapia
Anemia neonatal
Icterícia neonatal
Constrição
Cordão umbilical
Recém-nascido
topic Fototerapia
Anemia neonatal
Icterícia neonatal
Constrição
Cordão umbilical
Recém-nascido
Phototherapy
Neonatal anemia
Neonatal jaundice
Late cord clamping
dc.subject.eng.fl_str_mv Phototherapy
Neonatal anemia
Neonatal jaundice
Late cord clamping
description Background: Recently, late umbilical cord clamping is generally recommended, which decreases neonatal anemia; however, it may also increase neonatal jaundice and some other poor outcomes. Objectives: We here attempted to determine whether late clamping actually increases the incidence of phototherapy for jaundice and other poor outcomes of the term “low-risk newborns”. Methods: With the approval of the Brazilian Registry of Clinical Trials (REBEC), a total of 357 low-risk newborns (singleton, uncomplicated pregnancy/delivery, in a Brazilian public institution) were randomized into two groups: group I (n = 114): cord clamping < 1 minute (early clamping) or group II (n = 243): cord clamping between 1 - 3 minutes (late clamping). Statistics were used appropriately (i.e., measures of central tendency, dispersion for continuous variables, Shapiro-Wilk, Mann-Whitney test, or Chi-square test). Results: Phototherapy was performed in 5.3% in both groups. Also, there were no statistical differences in the occurrence of secondary outcomes, such as sepsis, neonatal ICU admission, and transient tachypnea of the newborns: i.e., 0.9%, 15.8%, and 3.5%, respectively for group I versus 1.2%, 15.6%, and 5.8%, respectively for group II. Conclusion: Late umbilical cord clamping does not increase the need for phototherapy in low-risk neonates. This result corroborates the current recommendation of late cord clamping, whenever appropriate.
publishDate 2022
dc.date.accessioned.fl_str_mv 2022-04-13T04:51:36Z
dc.date.issued.fl_str_mv 2022
dc.type.driver.fl_str_mv Estrangeiro
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dc.identifier.issn.pt_BR.fl_str_mv 2160-8806
dc.identifier.nrb.pt_BR.fl_str_mv 001139443
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dc.language.iso.fl_str_mv eng
language eng
dc.relation.ispartof.pt_BR.fl_str_mv Open journal of obstetrics and gynecology. Irvine. Vol. 12, no. 3 (2022), p. 193-200.
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
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dc.source.none.fl_str_mv reponame:Repositório Institucional da UFRGS
instname:Universidade Federal do Rio Grande do Sul (UFRGS)
instacron:UFRGS
instname_str Universidade Federal do Rio Grande do Sul (UFRGS)
instacron_str UFRGS
institution UFRGS
reponame_str Repositório Institucional da UFRGS
collection Repositório Institucional da UFRGS
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