Proteinuria: clinical and laboratory approach

Proteinuria is a strong indicator of renal disease and it is present in many syndromes. Our objective is to review the pathophysiological mechanisms that lead to proteinuria, as well as the available methods for its detection and quantitation, including the dipstick, 24-hour proteinuria, and the uri...

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Detalhes bibliográficos
Autores: V. Morales, José, Garcez, Joana, Weber, Raimar, L. Klamt, Charles, Barros, Elvino
Formato: artículo
Estado:Versión publicada
Fecha de publicación:2022
País:Brasil
Recursos:Universidade Federal do Rio Grande do Sul (UFRGS)
Repositorio:Clinical and Biomedical Research
Idioma:portugués
OAI Identifier:oai:seer.ufrgs.br:article/125388
Acesso em linha:https://seer.ufrgs.br/index.php/hcpa/article/view/125388
Access Level:acceso abierto
Palavra-chave:Proteinúria
glomerulonefrite
síndrome nefrótica
Proteinuria
glomerulonephritis
nephrotic syndrome
Descrição
Resumo:Proteinuria is a strong indicator of renal disease and it is present in many syndromes. Our objective is to review the pathophysiological mechanisms that lead to proteinuria, as well as the available methods for its detection and quantitation, including the dipstick, 24-hour proteinuria, and the urinary protein-creatinine ratio. We gave special attention to clinical evaluation of proteinuric patients, including the available exams and the situations in which they are indicated. An algorithm for the investigation of patients with proteinuria is presented. We also emphasized the importance of persistent proteinuria in its relation with the progression of renal diseases.