Nutritional assessment methods for zinc supplementation inprepubertal non-zinc-deficient children

Background: Zinc is an essential nutrient that is required for numerous metabolic functions, and zincdeficiency results in growth retardation, cell-mediated immune dysfunction, and cognitive impairment.Objective: This study evaluated nutritional assessment methods for zinc supplementation in prepube...

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Detalhes bibliográficos
Autores: Lopes, Márcia Marília Gomes Dantas, Brito, Naira Josele Neves de, Rocha, Érika Dantas de Medeiros, França, Mardone Cavalcante, Almeida, Maria das Graças de, Brandão Neto, José
Formato: artículo
Estado:Versión publicada
Fecha de publicación:2015
País:Brasil
Recursos:Universidade Federal do Rio Grande do Norte (UFRN)
Repositorio:Repositório Institucional da UFRN
Idioma:inglés
OAI Identifier:oai:repositorio.ufrn.br:123456789/62872
Acesso em linha:https://repositorio.ufrn.br/handle/123456789/62872
http://dx.doi.org/10.3402/fnr.v59.29733
Access Level:acceso abierto
Palavra-chave:Zinc supplementation
Bioelectrical impedance vector analysis
Phase angle
Dietary assessment
Children
Descrição
Resumo:Background: Zinc is an essential nutrient that is required for numerous metabolic functions, and zincdeficiency results in growth retardation, cell-mediated immune dysfunction, and cognitive impairment.Objective: This study evaluated nutritional assessment methods for zinc supplementation in prepubertal non-zinc-deficient children.Design: We performed a randomised, controlled, triple-blind study. The children were divided into a controlgroup (10% sorbitol,n 31) and an experimental group (10 mg Zn/day,n 31) for 3 months. Anthropometricand dietary assessments as well as bioelectrical measurements were performed in all children.Results: Our study showed (1) an increased body mass index for age and an increased phase angle in theexperimental group; (2) a positive correlation between nutritional assessment parameters in both groups; (3)increased soft tissue, and mainly fat-free mass, in the body composition of the experimental group, asdetermined using bioelectrical impedance vector analysis; (4) increased consumption of all nutrients,including zinc, in the experimental group; and (5) an increased serum zinc concentration in both groups(pB0.0001).Conclusions: Given that a reference for body composition analysis does not exist for intervention studies,longitudinal studies are needed to investigate vector migration during zinc supplementation. These resultsreinforce the importance of employing multiple techniques to assess the nutritional status of populations.