Structural optimization of PNIPAM-derived thermoresponsive polymers: a computational approach employing artificial neural networks and genetic algorithms

In this study, artificial neural networks (ANNs) and genetic algorithms (GAs) are employed together to design optimized polymeric structures with superior cloud points. The database from a previous study of polymer synthesis with thermoresponsive polymers was used to create ANN-based models, which e...

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Detalhes bibliográficos
Autores: Silveira, Kelly Cristine da, Hille, Tony, Gago, Matheus Moraes, Teixeira, Josiele da Silva, Leite, Guilherme Anunciação, Gois, Jonathan Nogueira, Silva Neto, Antônio José da
Formato: artículo
Estado:Versión publicada
Fecha de publicación:2024
País:Brasil
Recursos:Universidade Federal de Santa Maria (UFSM)
Repositorio:Revista Ciência e Natura (Online)
Idioma:inglés
OAI Identifier:oai:ojs.pkp.sfu.ca:article/87076
Acesso em linha:https://periodicos.ufsm.br/cienciaenatura/article/view/87076
Access Level:acceso abierto
Palavra-chave:Poly(N-isopropylacrylamide)
Artificial neural networks
Genetic algorithms
Smart polymers
Poli(N-isopropilacrilamida)
Redes neurais artificiais
Algoritmos genéticos
Polímeros inteligentes
Descrição
Resumo:In this study, artificial neural networks (ANNs) and genetic algorithms (GAs) are employed together to design optimized polymeric structures with superior cloud points. The database from a previous study of polymer synthesis with thermoresponsive polymers was used to create ANN-based models, which enabled the formulation and solution of the inverse problem using the GA. The regressors, with an average RMSE of less than 0.7 ºC, were used in the polymer evolution process over 20 generations. Mutation and selection operations led to the creation of 10 novel hybrid macromolecules with an average cloud point of 80 ºC. Furthermore, the special roles of some chemical groups are recognized and favor the structural mapping of PNIPAM-based materials. The computational approach presented here demonstrates that it is a promising tool in the development of new materials.