Phenylethylpyranone and aristolochic acid derivatives from Aristolochia urupaensis

A new pyranone, (S)-2-(4-hydroxyphenylethyl)-6-methyl-2,3-dihydro-4H-pyran-4-one, with unusual carbon skeleton, and three new aristolochic acid derivatives (7-O-methylaristolochic acid F, sodium 7-O-methylaristolochate F and sodium aristolochate F) were isolated from Aristolochia urupaensis (Aristol...

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Detalhes bibliográficos
Autores: Holzbach, Juliana C. [UNESP], Nascimento, Isabele R. [UNESP], Lopes, Lucia M. X. [UNESP]
Formato: artículo
Estado:Versión publicada
Fecha de publicación:2017
País:Brasil
Recursos:Universidade Estadual Paulista (UNESP)
Repositorio:Repositório Institucional da UNESP
Idioma:inglés
OAI Identifier:oai:repositorio.unesp.br:11449/179179
Acesso em linha:http://dx.doi.org/10.21577/0103-5053.20170059
http://hdl.handle.net/11449/179179
Access Level:acceso abierto
Palavra-chave:Aristolochia urupaensis
Aristolochiaceae
Phenylethylpyranone
Sodium aristolochate
Descrição
Resumo:A new pyranone, (S)-2-(4-hydroxyphenylethyl)-6-methyl-2,3-dihydro-4H-pyran-4-one, with unusual carbon skeleton, and three new aristolochic acid derivatives (7-O-methylaristolochic acid F, sodium 7-O-methylaristolochate F and sodium aristolochate F) were isolated from Aristolochia urupaensis (Aristolochiaceae) stems together with 31 known compounds. The structures of the compounds were determined by spectroscopic analyses, including Fourier transform infrared (FTIR) and 1D and 2D nuclear magnetic resonance (NMR) techniques, and high-resolution mass spectrometry (HRMS).