Early dissemination of OXA-72-producing Acinetobacter baumannii strain in Colombia: a case report

Nosocomial infections caused by carbapenem-resistant Acinetobacter baumannii isolates have reached epidemic levels in past decades. Currently this microorganism is responsible for outbreaks of difficult eradication and with high mortality rates worldwide. We herein report a rare case of an OXA-72-pr...

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Detalhes bibliográficos
Autores: Saavedra, Sandra Yamile, Cayô, Rodrigo [UNIFESP], Gales, Ana Cristina [UNIFESP], Leal, Aura Lucia, Saavedra, Carlos Humberto
Tipo de documento: artigo
Estado:Versão publicada
Data de publicação:2014
País:Brasil
Recursos:Universidade Federal de São Paulo (UNIFESP)
Repositório:Repositório Institucional da UNIFESP
Idioma:inglês
OAI Identifier:oai:repositorio.unifesp.br:11600/8746
Acesso em linha:http://dx.doi.org/10.1016/j.bjid.2014.05.017
http://repositorio.unifesp.br/handle/11600/8746
Access Level:Acceso aberto
Palavra-chave:Acinetobacter baumannii
Carbapenem-resistance
Oxacillinase
Colombia
Descrição
Resumo:Nosocomial infections caused by carbapenem-resistant Acinetobacter baumannii isolates have reached epidemic levels in past decades. Currently this microorganism is responsible for outbreaks of difficult eradication and with high mortality rates worldwide. We herein report a rare case of an OXA-72-producing A. baumannii isolate colonizing a 47-year-old male patient with peritonitis due to abdominal stab wound, four years earlier than the first report of this carbapenemase in Acinetobacter pittii in Colombia. Although OXA-72 presents a low prevalence compared with OXA-23, our study demonstrated that A. baumannii isolates carrying the blaOXA-72 gene were present in the hospital environment in Colombia and could act as a reservoir for further spread to other Acinetobacter species, like A. pittii, causing carbapenem-resistance.