Implementation of a New Experimental Animal Model - Zebrafish
Danio rerio (zebrafish, paulistinha) is a freshwater small fish that has been used as an animal model for studies of several human diseases. Its characteristics of being easily bred and reproduced and its laboratory housing methods are well established. It requires some basic care and the acquisitio...
| Autores: | , , , , , , |
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| Tipo de documento: | artigo |
| Estado: | Versão publicada |
| Data de publicação: | 2009 |
| País: | Brasil |
| Recursos: | Universidade Federal do Rio Grande do Sul (UFRGS) |
| Repositório: | Clinical and Biomedical Research |
| Idioma: | português |
| OAI Identifier: | oai:seer.ufrgs.br:article/7981 |
| Acesso em linha: | https://seer.ufrgs.br/index.php/hcpa/article/view/7981 |
| Access Level: | Acceso aberto |
| Palavra-chave: | Zebrafish Danio rerio Modelo Animal Zebrafisch danio rerio |
| Resumo: | Danio rerio (zebrafish, paulistinha) is a freshwater small fish that has been used as an animal model for studies of several human diseases. Its characteristics of being easily bred and reproduced and its laboratory housing methods are well established. It requires some basic care and the acquisition of specific low-cost equipment. Since this fish has already been considered a good human disease model, it may serve as a powerful preclinical platform for the study of molecular events, therapeutic strategies, and for evaluating the physiological mechanisms of some pathologies. The Laboratory of Experimental Hepatology and Gastroenterology (LEHG) of the Research Center of Hospital de Clínicas de Porto Alegre initiated studies with the zebrafish in 2008, presented here. |
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