Effects of Rosmarinus officinalis essential oil on germ tube formation by Candida albicans isolated from denture wearers

Introduction: The aim of this study was to investigate the effects of Rosmarinus offi cinalis essential oil on germ tube formation by Candida albicans isolated from denture wearers. Methods: Ten C. albicans isolates recovered from denture wearers were tested using 10% fetal bovine serum with or with...

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Bibliographic Details
Authors: Gauch, Lurdete Maria Rocha, Silveira-Gomes, Fabíola, Esteves, Renata Antunes, Pedrosa, Simone Soares, Gurgel, Ely Simone Cajueiro, Arruda, Alberto Cardoso, Silva, Silvia Helena Marques da
Format: article
Status:Published version
Publication Date:2014
Country:Brasil
Institution:Instituto Evandro Chagas (IEC)
Repository:Repositório Digital do Instituto Evandro Chagas (Patuá)
Language:English
OAI Identifier:oai:patua.iec.gov.br:iec/434
Online Access:https://patua.iec.gov.br/handle/iec/434
Access Level:Open access
Keyword:Candida albicans
Rosmarinus officinalis / uso terapêutico
Antifúngicos / uso terapêutico
Belém (PA)
Description
Summary:Introduction: The aim of this study was to investigate the effects of Rosmarinus offi cinalis essential oil on germ tube formation by Candida albicans isolated from denture wearers. Methods: Ten C. albicans isolates recovered from denture wearers were tested using 10% fetal bovine serum with or without 4% R. offi cinalis essential oil. Results: The essential oil from R. offi cinalis completely inhibited germ tube formation in the investigated C. albicans isolates. Conclusions: The results demonstrate that the essential oil of R. offi cinalis modulates C. albicans pathogenicity through its primary virulence factor (i.e., germ tube formation was suppressed).

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