Selective fetoscopic laser photocoagulation of superficial placental anastomoses for the treatment of severe twin-twin transfusion syndrome

OBJECTIVE: To report our initial institutional experience with fetoscopic laser photocoagulation of placental anastomoses in severe twin-twin transfusion syndrome using a 1.0 mm endoscope. METHODS: Between July 2006 and June 2008, 19 monochorionic diamniotic twin pregnancies complicated by severe TT...

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Detalhes bibliográficos
Autores: Ruano, Rodrigo, Brizot, Maria de Lourdes, Liao, Adolfo Wenjaw, Zugaib, Marcelo
Tipo de documento: artigo
Estado:Versão publicada
Data de publicação:2009
País:Brasil
Recursos:Universidade de São Paulo (USP)
Repositório:Clinics
Idioma:inglês
OAI Identifier:oai:revistas.usp.br:article/17975
Acesso em linha:https://www.revistas.usp.br/clinics/article/view/17975
Access Level:Acceso aberto
Palavra-chave:Twin-twin transfusion syndrome
Fetal surgery
Fetoscopy
Prenatal diagnosis
Laser
Fetal therapy
Placenta
Monochorionic twins
Descrição
Resumo:OBJECTIVE: To report our initial institutional experience with fetoscopic laser photocoagulation of placental anastomoses in severe twin-twin transfusion syndrome using a 1.0 mm endoscope. METHODS: Between July 2006 and June 2008, 19 monochorionic diamniotic twin pregnancies complicated by severe TTTS (Quintero stages III and IV) underwent fetoscopic laser therapy. Perinatal data were prospectively collected and compared according to the Quintero stages. RESULTS: Nine patients were classified as stage III and ten as stage IV. The Mean gestational ages at diagnosis and procedure were 20 (range: 17-25) and 22.0 (range: 19.0-26.0) weeks, respectively, with no statistical difference between the two groups. Preterm premature rupture of the membranes occurred in two cases (10.5%), and spontaneous preterm delivery in eight (42.1%). Overall mean gestational age at delivery was 32.1 (range: 26.0-38.0) weeks. Prematurity was more severe in stage IV patients (p