Inhibition of Acetylcholinesterase and Fatty Acid Composition in Theobroma grandiflorum Seeds

Theobroma grandiflorum is an important fruit tree from Sterculiaceae family, native to the Brazilian Amazon, known in the region as cupuaçu. The seeds have a high fat content (24%) with characteristics that resemble those of cocoa (Theobroma cacao) butter with potential applications in the...

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Bibliographic Details
Authors: Yanes, Casandra Valentina Itriago, de Melo Filho, Antonio Alves, Ribeiro, Pedro Rômulo Estevam, Melo, Ana Cristina Gonçalves Reis, Takahashi, Jacqueline Aparecida, Ferraz, Vany Perpetua, Mozombite, Diana Maruja Sagama, dos Santos, Ricardo Carvalho
Format: article
Status:Published version
Publication Date:2017
Country:Brasil
Institution:Universidade Federal de Mato Grosso do Sul (UFMS)
Repository:Orbital - The Electronic Journal of Chemistry (Campo Grande)
Language:English
OAI Identifier:oai:periodicos.ufms.br:article/16489
Online Access:https://periodicos.ufms.br/index.php/orbital/article/view/16489
Access Level:Open access
Keyword:brazilian amazon
cupuaçu
oleic acid
stearic acid
palmitic acid
Alzheimer disease
Description
Summary:Theobroma grandiflorum is an important fruit tree from Sterculiaceae family, native to the Brazilian Amazon, known in the region as cupuaçu. The seeds have a high fat content (24%) with characteristics that resemble those of cocoa (Theobroma cacao) butter with potential applications in the cosmetic, pharmaceutical and food industries. The main objective of this work was to explore the seed fats from T. grandiflorum that were analyzed for fatty acid composition by Gas Chromatography with Flame Ionization Detector (GC-FID) and to analyze their activity for acetylcholinesterase inhibition. Chromatographic analysis provided detection of nine fatty acids. The major fatty acids found in the species were oleic (40.0%), stearic (32.7%), arachidic (10.4%) and palmitic (8.0%). The acetylcholinesterase inhibition by fats from seeds was over 40.48%. DOI: http://dx.doi.org/10.17807/orbital.v0i0.894