Circulation of multidrug-resistant (MDR) and extensively drug-resistant (XDR) Mycobacterium tuberculosis strains in Mexico

Emergence of Extensively Drug-Resistant (XDR) Tuberculosis (TB) is an important public health problem worldwide. In Mexico, the extent of circulation of XDR-TB strains is unknown. Here, the drug-resistance patterns of TB isolates collected in Mexico between 2006 and 2008 were analyzed. Among 137 TB...

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Authors: Vazquez-Chacon, Carlos A., Martinez-Guarneros, Armando, Campos, Susana Balandrano, Herrera, Julieta Luna, Bäcker, Claudia, Maria Gonçalves Rossi, Livia [UNESP], Fonseca-Coronado, Salvador, Ruiz-Tovar, Karina, Carpio-Pedroza, Juan C., Vaughan, Gilberto, Escobar-Gutierrez, Alejandro
Format: article
Status:Published version
Publication Date:2014
Country:Brasil
Institution:Universidade Estadual Paulista (UNESP)
Repository:Repositório Institucional da UNESP
Language:English
OAI Identifier:oai:repositorio.unesp.br:11449/220286
Online Access:http://dx.doi.org/10.3844/ajidsp.2014.177.181
http://hdl.handle.net/11449/220286
Access Level:Open access
Keyword:MDR
Mexico
Pre-XDR
Tuberculosis
XDR
Description
Summary:Emergence of Extensively Drug-Resistant (XDR) Tuberculosis (TB) is an important public health problem worldwide. In Mexico, the extent of circulation of XDR-TB strains is unknown. Here, the drug-resistance patterns of TB isolates collected in Mexico between 2006 and 2008 were analyzed. Among 137 TB isolates, (58%) were classified as MDR exclusively, (33%) were Pre-XDR and (9%) were assigned as XDR. The results confirmed the circulation of Pre-XDR and XDR-TB in Mexico. Surveillance and drug-susceptibility testing should be improved in Mexico to monitor the circulation of XDR strains.

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