Effects of fasting on the interplay between temperature and Trypanosoma cruzi infection on the life cycle of the Chagas disease vector Rhodnius prolixus.

Pasteur’s institute awarded to H.L. A. A. G. (CNPq) productivity grant [grant number 304862/2022-3].

Detalhes bibliográficos
Autores: Loshouarn, Henri, Guarneri, Alessandra Aparecida
Tipo de documento: artigo
Estado:Versão publicada
Data de publicação:2024
País:Brasil
Recursos:Fundação Oswaldo Cruz (FIOCRUZ)
Repositório:Repositório Institucional da FIOCRUZ (ARCA)
Idioma:inglês
OAI Identifier:oai:arca.fiocruz.br:icict/68317
Acesso em linha:https://arca.fiocruz.br/handle/icict/68317
Access Level:Acceso aberto
Palavra-chave:Rhodnius prolixus
Triatomíneos
Doença de Chagas
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dc.title.none.fl_str_mv Effects of fasting on the interplay between temperature and Trypanosoma cruzi infection on the life cycle of the Chagas disease vector Rhodnius prolixus.
title Effects of fasting on the interplay between temperature and Trypanosoma cruzi infection on the life cycle of the Chagas disease vector Rhodnius prolixus.
spellingShingle Effects of fasting on the interplay between temperature and Trypanosoma cruzi infection on the life cycle of the Chagas disease vector Rhodnius prolixus.
Loshouarn, Henri
Rhodnius prolixus
Triatomíneos
Doença de Chagas
title_short Effects of fasting on the interplay between temperature and Trypanosoma cruzi infection on the life cycle of the Chagas disease vector Rhodnius prolixus.
title_full Effects of fasting on the interplay between temperature and Trypanosoma cruzi infection on the life cycle of the Chagas disease vector Rhodnius prolixus.
title_fullStr Effects of fasting on the interplay between temperature and Trypanosoma cruzi infection on the life cycle of the Chagas disease vector Rhodnius prolixus.
title_full_unstemmed Effects of fasting on the interplay between temperature and Trypanosoma cruzi infection on the life cycle of the Chagas disease vector Rhodnius prolixus.
title_sort Effects of fasting on the interplay between temperature and Trypanosoma cruzi infection on the life cycle of the Chagas disease vector Rhodnius prolixus.
dc.creator.none.fl_str_mv Loshouarn, Henri
Guarneri, Alessandra Aparecida
author Loshouarn, Henri
author_facet Loshouarn, Henri
Guarneri, Alessandra Aparecida
author_role author
author2 Guarneri, Alessandra Aparecida
author2_role author
dc.subject.other.none.fl_str_mv Rhodnius prolixus
Triatomíneos
Doença de Chagas
topic Rhodnius prolixus
Triatomíneos
Doença de Chagas
description Pasteur’s institute awarded to H.L. A. A. G. (CNPq) productivity grant [grant number 304862/2022-3].
publishDate 2024
dc.date.issued.fl_str_mv 2024
dc.date.accessioned.fl_str_mv 2025-01-29T17:39:31Z
dc.date.available.fl_str_mv 2025-01-29T17:39:31Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
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status_str publishedVersion
dc.identifier.citation.fl_str_mv LOSHOUARN, Henri; GUARNERI, Alessandra Aparecida. Effects of fasting on the interplay between temperature and Trypanosoma cruzi infection on the life cycle of the Chagas disease vector Rhodnius prolixus. PLoS Negl Trop Dis., v. 18, n. 11, e0012665, 2024.
dc.identifier.uri.fl_str_mv https://arca.fiocruz.br/handle/icict/68317
dc.identifier.issn.none.fl_str_mv 1935-2735
dc.identifier.doi.none.fl_str_mv 10.1371/journal.pntd.0012665
identifier_str_mv LOSHOUARN, Henri; GUARNERI, Alessandra Aparecida. Effects of fasting on the interplay between temperature and Trypanosoma cruzi infection on the life cycle of the Chagas disease vector Rhodnius prolixus. PLoS Negl Trop Dis., v. 18, n. 11, e0012665, 2024.
1935-2735
10.1371/journal.pntd.0012665
url https://arca.fiocruz.br/handle/icict/68317
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv Public Library of Science
publisher.none.fl_str_mv Public Library of Science
dc.source.none.fl_str_mv reponame:Repositório Institucional da FIOCRUZ (ARCA)
instname:Fundação Oswaldo Cruz (FIOCRUZ)
instacron:FIOCRUZ
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instacron_str FIOCRUZ
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reponame_str Repositório Institucional da FIOCRUZ (ARCA)
collection Repositório Institucional da FIOCRUZ (ARCA)
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spelling 2025-01-29T17:39:31Z2025-01-29T17:39:31Z2024LOSHOUARN, Henri; GUARNERI, Alessandra Aparecida. Effects of fasting on the interplay between temperature and Trypanosoma cruzi infection on the life cycle of the Chagas disease vector Rhodnius prolixus. PLoS Negl Trop Dis., v. 18, n. 11, e0012665, 2024.1935-2735https://arca.fiocruz.br/handle/icict/6831710.1371/journal.pntd.0012665Pasteur’s institute awarded to H.L. A. A. G. (CNPq) productivity grant [grant number 304862/2022-3].Fundação Oswaldo Cruz. Instituto René Rachou. Grupo de Comportamento de Vetores e Interação de Patógenos. Belo Horizonte, MG, Brasil.Fundação Oswaldo Cruz. Instituto René Rachou. Grupo de Comportamento de Vetores e Interação de Patógenos. Belo Horizonte, MG, Brasil.Rhodnius prolixus, a triatomine insect, is one of the most important vectors of Chagas disease in South America. Its interaction with the parasite Trypanosoma cruzi, the causative agent of this disease, is known to be deeply affected by ambient temperature and the nutritional status of the insect vector. In this study, we investigated how starvation affects the life cycle of R. prolixus and the population dynamics of the parasite inside the intestine of the vector at four temperatures ranging from 24°C to 30°C. The weights and molting times of chronically infected and uninfected insects were monitored through repeated 30-day fasting periods from first instar to adult stage, assessing their capacity to retain blood meal weight between developmental stages and tracking parasite concentrations in their urine. Our results demonstrate that ambient temperature is a crucial factor affecting the resistance of R. prolixus to starvation, as survival, body weight, and weight retention greatly decreased in high temperature treatments. Furthermore, we showed that temperature significantly influenced whether T. cruzi established an infection in early instars, with few insects developing infections at the lowest and highest temperature treatments. Additionally, we discovered that a fasting period of 30 days induces a steady decrease in parasite populations in the vector over its lifetime. Infection by T. cruzi had no effect on the survival, molting time, and nutritional factors monitored in our protocol. Our results highlight the importance of nutrition as a determining factor for the development of the vector and the parasite, providing valuable insights for elucidating the complex interplay between temperature and nutrition in shaping the epidemiology of Chagas disease in a changing climate.engPublic Library of ScienceRhodnius prolixusTriatomíneosDoença de ChagasEffects of fasting on the interplay between temperature and Trypanosoma cruzi infection on the life cycle of the Chagas disease vector Rhodnius prolixus.info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLoshouarn, HenriGuarneri, Alessandra AparecidaLICENSElicense.txtlicense.txttext/plain; charset=utf-82991https://arca.fiocruz.br/bitstreams/c704a24c-0e4b-4325-b911-34334ae0cb5e/download5a560609d32a3863062d77ff32785d58MD51falseAnonymousREADORIGINALEffects of fasting on the interplay between.pdfEffects of fasting on the interplay between.pdfapplication/pdf1477432https://arca.fiocruz.br/bitstreams/2cebd88a-8c70-4bd0-a503-32dcd9e85f4b/download4e9c81d688c14740a823ca7beac2c7b2MD52trueAnonymousREADTEXTEffects of fasting on the interplay between.pdf.txtEffects of fasting on the interplay between.pdf.txtExtracted texttext/plain70294https://arca.fiocruz.br/bitstreams/e2102528-a1fb-4271-b2be-99edf18c34ab/download655281b20a60d8cf96e084becf37e100MD515falseAnonymousREADTHUMBNAILEffects of fasting on the interplay between.pdf.jpgEffects of fasting on the interplay between.pdf.jpgGenerated Thumbnailimage/jpeg38906https://arca.fiocruz.br/bitstreams/65c0bf9c-56c8-418d-8435-8996cbca6b28/download15e32b4228133d94264b02acccad0b93MD516falseAnonymousREADicict/683172025-12-16 06:30:37.913open.accessoai:arca.fiocruz.br:icict/68317https://arca.fiocruz.brRepositório InstitucionalPUBhttps://www.arca.fiocruz.br/oai/requestrepositorio.arca@fiocruz.bropendoar:21352025-12-16T09:30:37Repositório Institucional da FIOCRUZ (ARCA) - 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