Potential Benefits of Probiotics, Prebiotics, and Synbiotics on the Intestinal Microbiota of the Elderly

Although the scientific evidence has shown that the aging process may affect the composition and metabolic activity of human intestinal microbiota and its interaction with the immune system, this relationship still requires a better understanding. Probiotics, prebiotics, and synbiotics have shown th...

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Detalhes bibliográficos
Autores: Bedani, Raquel, Isay Saad, Susana Marta, Sivieri, Katia [UNESP]
Tipo de documento: capítulo de livro
Estado:Versão publicada
Data de publicação:2016
País:Brasil
Recursos:Universidade Estadual Paulista (UNESP)
Repositório:Repositório Institucional da UNESP
Idioma:inglês
OAI Identifier:oai:repositorio.unesp.br:11449/228151
Acesso em linha:http://dx.doi.org/10.1016/B978-0-12-802189-7.00037-X
http://hdl.handle.net/11449/228151
Access Level:Acceso aberto
Palavra-chave:Aging
Gut health
Gut microbiota
Modulation
Prebiotics
Probiotics
Synbiotics
Descrição
Resumo:Although the scientific evidence has shown that the aging process may affect the composition and metabolic activity of human intestinal microbiota and its interaction with the immune system, this relationship still requires a better understanding. Probiotics, prebiotics, and synbiotics have shown the potential to alleviate common gastrointestinal problems in elderly people by modulating microbial activity and immune status. In spite of the promising results, more intervention trials with probiotics and/or prebiotics are needed to elucidate the mechanisms of action involved and to undoubtedly demonstrate their effectiveness in aged people. The aim of this chapter is to focus on the gut microbial changes associated with aging and the potential benefits of pro-, pre-, and synbiotics to modulate the intestinal microbiota and to contribute for the maintenance of the health and well-being in the elderly.