Low-cost paper-based sensors modified with curcumin for the detection of ochratoxin a in beverages.

Ochratoxin A (OTA) is a mycotoxin that can contaminate food and is produced by fungal species such as Aspergillus carbonarius, Penicillium verrucosum, Aspergillus ochraceus, and Aspergillus niger [1]. OTA poses significant risks to both humans and animals, as it can cause mutagenic, carcinogenic, te...

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Authors: SANTOS, D. M. dos, MIGLIORINI, F. L., COATRINI-SOARES, A., SOARES, J., MATTOSO, L. H. C., OLIVEIRA, O. N., CORREA, D. S.
Format: article
Status:Published version
Publication Date:2024
Country:Brasil
Institution:Empresa Brasileira de Pesquisa Agropecuária (Embrapa)
Repository:Repositório Institucional da EMBRAPA (Repository Open Access to Scientific Information from EMBRAPA - Alice)
Language:English
OAI Identifier:oai:www.alice.cnptia.embrapa.br:doc/1160713
Online Access:http://www.alice.cnptia.embrapa.br/alice/handle/doc/1160713
https://doi.org/10.1016/j.snr.2023.100184
Access Level:Open access
Keyword:Paper-based sensor
Electrochemical detection
Optical detection
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spelling Low-cost paper-based sensors modified with curcumin for the detection of ochratoxin a in beverages.Paper-based sensorElectrochemical detectionOptical detectionOchratoxin A (OTA) is a mycotoxin that can contaminate food and is produced by fungal species such as Aspergillus carbonarius, Penicillium verrucosum, Aspergillus ochraceus, and Aspergillus niger [1]. OTA poses significant risks to both humans and animals, as it can cause mutagenic, carcinogenic, teratogenic, hemorrhagic, hepatotoxic, estrogenic, immunotoxic, dermatoxic, nephrotoxic, and neurotoxic effects [2–5]. Contamination with OTA can occur at various stages, including during cultivation, post-harvest, and transportation or storage of food produce. Commonly affected food items include dried fruits, cereals, nuts, corn, oats, coffee, grape juice, wine, wheat, and beer [6–9]. OTA is stable in most food-processing conditions, making it a persistent concern in the realm of food safety [4]. Consumption of OTA-contaminated food has emerged as a substantial public health issue that requires immediate attention. Currently, analytical methods such as enzyme-linked immunosorbent assay (ELISA) [10] and chromatographic assays [11] are employed to detect OTA and monitor food quality. However, these approaches are time-consuming and expensive and require sample preparation and trained personnel to operate the instruments. To address these limitations, alternative systems have been proposed, including electrochemical and optical sensors, which offer simpler procedures for detecting OTA traces [4]. Surface functionalization [5,12,13] can further enhance the performance of these sensors. Notably, paper-based sensors show great promise as they fulfill the requirements for point-of-attention food monitoring, are low-cost, portable, and versatile [14,15]. Additionally, functionalization can be accomplished using a wide range of raw, biodegradable materials [16–18]. In this study, we present an innovative paper-based sensor functionalized with curcumin for the optical and electrochemical detection of ochratoxin A (OTA), as illustrated in Scheme 1. Curcumin is a highly promising sensing element due to its affordability, widespread availability, non-toxicity, and pronounced fluorescence that is quenched in the presence of OTA [19–25]. Notably, curcumin also possesses redox-active properties, with two distinct redox centers: a β-diketone.ANDREY COATRINI-SOARESUNIVERSITY OF SÃO PAULO (USP)LUIZ HENRIQUE CAPPARELLI MATTOSO, CNPDIAUNIVERSITY OF SAO PAULO (USP)DANIEL SOUZA CORREA, CNPDIA.2024-01-11T14:34:00Z2024-01-11T14:34:00Z2024-01-112024info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article11 p.Sensors and Actuators Reports, v. 7, 100184, 2024.2666-0539http://www.alice.cnptia.embrapa.br/alice/handle/doc/1160713https://doi.org/10.1016/j.snr.2023.100184enginfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da EMBRAPA (Repository Open Access to Scientific Information from EMBRAPA - Alice)instname:Empresa Brasileira de Pesquisa Agropecuária (Embrapa)instacron:EMBRAPASANTOS, D. M. dosMIGLIORINI, F. L.COATRINI-SOARES, A.SOARES, J.MATTOSO, L. H. C.OLIVEIRA, O. N.CORREA, D. S.2025-03-16T05:14:33Zoai:www.alice.cnptia.embrapa.br:doc/1160713Repositório InstitucionalPUBhttps://www.alice.cnptia.embrapa.br/oai/requestcg-riaa@embrapa.bropendoar:21542025-03-16T05:14:33Repositório Institucional da EMBRAPA (Repository Open Access to Scientific Information from EMBRAPA - Alice) - Empresa Brasileira de Pesquisa Agropecuária (Embrapa)false
dc.title.none.fl_str_mv Low-cost paper-based sensors modified with curcumin for the detection of ochratoxin a in beverages.
title Low-cost paper-based sensors modified with curcumin for the detection of ochratoxin a in beverages.
spellingShingle Low-cost paper-based sensors modified with curcumin for the detection of ochratoxin a in beverages.
SANTOS, D. M. dos
Paper-based sensor
Electrochemical detection
Optical detection
title_short Low-cost paper-based sensors modified with curcumin for the detection of ochratoxin a in beverages.
title_full Low-cost paper-based sensors modified with curcumin for the detection of ochratoxin a in beverages.
title_fullStr Low-cost paper-based sensors modified with curcumin for the detection of ochratoxin a in beverages.
title_full_unstemmed Low-cost paper-based sensors modified with curcumin for the detection of ochratoxin a in beverages.
title_sort Low-cost paper-based sensors modified with curcumin for the detection of ochratoxin a in beverages.
dc.creator.none.fl_str_mv SANTOS, D. M. dos
MIGLIORINI, F. L.
COATRINI-SOARES, A.
SOARES, J.
MATTOSO, L. H. C.
OLIVEIRA, O. N.
CORREA, D. S.
author SANTOS, D. M. dos
author_facet SANTOS, D. M. dos
MIGLIORINI, F. L.
COATRINI-SOARES, A.
SOARES, J.
MATTOSO, L. H. C.
OLIVEIRA, O. N.
CORREA, D. S.
author_role author
author2 MIGLIORINI, F. L.
COATRINI-SOARES, A.
SOARES, J.
MATTOSO, L. H. C.
OLIVEIRA, O. N.
CORREA, D. S.
author2_role author
author
author
author
author
author
dc.contributor.none.fl_str_mv ANDREY COATRINI-SOARES
UNIVERSITY OF SÃO PAULO (USP)
LUIZ HENRIQUE CAPPARELLI MATTOSO, CNPDIA
UNIVERSITY OF SAO PAULO (USP)
DANIEL SOUZA CORREA, CNPDIA.
dc.subject.por.fl_str_mv Paper-based sensor
Electrochemical detection
Optical detection
topic Paper-based sensor
Electrochemical detection
Optical detection
description Ochratoxin A (OTA) is a mycotoxin that can contaminate food and is produced by fungal species such as Aspergillus carbonarius, Penicillium verrucosum, Aspergillus ochraceus, and Aspergillus niger [1]. OTA poses significant risks to both humans and animals, as it can cause mutagenic, carcinogenic, teratogenic, hemorrhagic, hepatotoxic, estrogenic, immunotoxic, dermatoxic, nephrotoxic, and neurotoxic effects [2–5]. Contamination with OTA can occur at various stages, including during cultivation, post-harvest, and transportation or storage of food produce. Commonly affected food items include dried fruits, cereals, nuts, corn, oats, coffee, grape juice, wine, wheat, and beer [6–9]. OTA is stable in most food-processing conditions, making it a persistent concern in the realm of food safety [4]. Consumption of OTA-contaminated food has emerged as a substantial public health issue that requires immediate attention. Currently, analytical methods such as enzyme-linked immunosorbent assay (ELISA) [10] and chromatographic assays [11] are employed to detect OTA and monitor food quality. However, these approaches are time-consuming and expensive and require sample preparation and trained personnel to operate the instruments. To address these limitations, alternative systems have been proposed, including electrochemical and optical sensors, which offer simpler procedures for detecting OTA traces [4]. Surface functionalization [5,12,13] can further enhance the performance of these sensors. Notably, paper-based sensors show great promise as they fulfill the requirements for point-of-attention food monitoring, are low-cost, portable, and versatile [14,15]. Additionally, functionalization can be accomplished using a wide range of raw, biodegradable materials [16–18]. In this study, we present an innovative paper-based sensor functionalized with curcumin for the optical and electrochemical detection of ochratoxin A (OTA), as illustrated in Scheme 1. Curcumin is a highly promising sensing element due to its affordability, widespread availability, non-toxicity, and pronounced fluorescence that is quenched in the presence of OTA [19–25]. Notably, curcumin also possesses redox-active properties, with two distinct redox centers: a β-diketone.
publishDate 2024
dc.date.none.fl_str_mv 2024-01-11T14:34:00Z
2024-01-11T14:34:00Z
2024-01-11
2024
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv Sensors and Actuators Reports, v. 7, 100184, 2024.
2666-0539
http://www.alice.cnptia.embrapa.br/alice/handle/doc/1160713
https://doi.org/10.1016/j.snr.2023.100184
identifier_str_mv Sensors and Actuators Reports, v. 7, 100184, 2024.
2666-0539
url http://www.alice.cnptia.embrapa.br/alice/handle/doc/1160713
https://doi.org/10.1016/j.snr.2023.100184
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv 11 p.
dc.source.none.fl_str_mv reponame:Repositório Institucional da EMBRAPA (Repository Open Access to Scientific Information from EMBRAPA - Alice)
instname:Empresa Brasileira de Pesquisa Agropecuária (Embrapa)
instacron:EMBRAPA
instname_str Empresa Brasileira de Pesquisa Agropecuária (Embrapa)
instacron_str EMBRAPA
institution EMBRAPA
reponame_str Repositório Institucional da EMBRAPA (Repository Open Access to Scientific Information from EMBRAPA - Alice)
collection Repositório Institucional da EMBRAPA (Repository Open Access to Scientific Information from EMBRAPA - Alice)
repository.name.fl_str_mv Repositório Institucional da EMBRAPA (Repository Open Access to Scientific Information from EMBRAPA - Alice) - Empresa Brasileira de Pesquisa Agropecuária (Embrapa)
repository.mail.fl_str_mv cg-riaa@embrapa.br
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