Evolução das imunoglobunilas envolvidas na resposta imune de camundongos ao Schistosoma mansoni
The evolution of immunoglobulins involved in the immune response of mice infected with Schistosoma mansoni was studied by using plurispecific sera and the bi-dimensional immunoelectrophoresis technique. Determinations of the level of different immunoglobulins in infected animals and control groups w...
| Authors: | , , , |
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| Format: | article |
| Status: | Published version |
| Publication Date: | 1984 |
| Country: | Brasil |
| Institution: | Universidade de São Paulo (USP) |
| Repository: | Revista de Saúde Pública |
| Language: | Portuguese |
| OAI Identifier: | oai:revistas.usp.br:article/23213 |
| Online Access: | https://www.revistas.usp.br/rsp/article/view/23213 |
| Access Level: | Open access |
| Keyword: | Schistosoma mansoni Imunoglobulinas Esquistossomose mansônica Immunoglobulins Schistosomiasis |
| Summary: | The evolution of immunoglobulins involved in the immune response of mice infected with Schistosoma mansoni was studied by using plurispecific sera and the bi-dimensional immunoelectrophoresis technique. Determinations of the level of different immunoglobulins in infected animals and control groups which were mantained under similar conditions detected significant variations in both groups over the 8 weeks of observation. The study of the relationship (I/C) between the level of immunoglobulins of the infected animals (I) and that of corresponding control (C) showed that the infected animals presented a primary response (1-2 weeks after infection date) and a secondary response that was initiated in the 6th week of infection, with levels of IgA, IgG and IgM that were respectively 4.5, 3 and 2 times higher than those of corresponding control. |
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